Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christian Watermann"'
Autor:
Alireza Saraji, Kang Duan, Christian Watermann, Katharina Hempel, Marie C. Roesch, Rosemarie Krupar, Janine Stegmann-Frehse, Danny Jonigk, Mark Philipp Kuehnel, Wolfram Klapper, Axel S. Merseburger, Jutta Kirfel, Sven Perner, Anne Offermann, Verena Sailer
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13029 (2022)
Bone metastatic (BM) prostate cancer (PCa) belongs to the most lethal form of PCa, and therapeutic options are limited. Molecular profiling of metastases contributes to the understanding of mechanisms defining the bone metastatic niche. Our aim was t
Externí odkaz:
https://doaj.org/article/5722d2c076dd4b6783f6361a94770381
Autor:
Julika Ribbat-Idel, Franz F. Dressler, Rosemarie Krupar, Christian Watermann, Finn-Ole Paulsen, Patrick Kuppler, Luise Klapper, Anne Offermann, Barbara Wollenberg, Dirk Rades, Simon Laban, Markus Reischl, Karl-Ludwig Bruchhage, Christian Idel, Sven Perner
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: The approval of immune checkpoint inhibitors in combination with specific diagnostic biomarkers presents new challenges to pathologists as tumor tissue needs to be tested for expression of programmed death-ligand 1 (PD-L1) for a variety o
Externí odkaz:
https://doaj.org/article/15556fe55b95403ba64bfc0e98d5b371
Autor:
Julika Ribbat-Idel, Sven Perner, Patrick Kuppler, Luise Klapper, Rosemarie Krupar, Christian Watermann, Finn-Ole Paulsen, Anne Offermann, Karl-Ludwig Bruchhage, Barbara Wollenberg, Christian Idel
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Head and neck squamous cell carcinoma (HNSCC) represents a common cancer worldwide. Past therapeutic advances have not significantly improved HNSCC prognosis. Therefore, it is necessary to further stratify HNSCC, especially with recent ad
Externí odkaz:
https://doaj.org/article/feb464f6cd47446e8be525455f063825
Autor:
Alireza Saraji, Anne Offermann, Janine Stegmann-Frehse, Katharina Hempel, Duan Kang, Rosemarie Krupar, Christian Watermann, Danny Jonigk, Mark Philipp Kühnel, Jutta Kirfel, Sven Perner, Verena Sailer
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257416 (2021)
With the advance of precision medicine, the availability of tumor tissue for molecular analysis has become a limiting factor. This is particularly the case for bone metastases which are frequently occurring in cancer types such as prostate cancer. Du
Externí odkaz:
https://doaj.org/article/1e828c583f6242608f0c9b44085808a4
Autor:
Rosemarie Krupar, Anne Offermann, Duan Kang, Mark P. Kühnel, Alireza Saraji, Janine Stegmann-Frehse, Christian Watermann, Jutta Kirfel, Sven Perner, Katharina Hempel, Verena Sailer, Danny Jonigk
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257416 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257416 (2021)
With the advance of precision medicine, the availability of tumor tissue for molecular analysis has become a limiting factor. This is particularly the case for bone metastases which are frequently occurring in cancer types such as prostate cancer. Du
Autor:
Roland Schüle, Sven Perner, Christian Watermann, Duan Kang, Axel S. Merseburger, Alireza Saraji, Danny Jonigk, Janine Stegmann-Frehse, Stefan Duensing, Klaus Pantel, Zoran Culig, Anika Weingart, Wolfram Klapper, Jutta Kirfel, Rosemarie Kruper, Helge Taubert, Mark P. Kühnel, Anne Offermann, Marie C. Hupe, Achim Aigner, Verena Sailer
Publikováno v:
Carcinogenesis. 42(12)
Tripartite motif (TRIM) family proteins are post-translational protein modifiers with E3-ubiquitin ligase activity, thereby involved in various biological processes. The molecular mechanisms driving prostate cancer (PCa) bone metastasis (BM) are inco
Autor:
Johannes Brägelmann, Mark P. Kühnel, Barbara Wollenberg, Eva Dreyer, Lars Tharun, Christian Rosero, Helen Pasternack, Rosemarie Krupar, Sven Perner, Patrick Kuppler, Anne Offermann, Jacqueline Nathansen, Danny Jonigk, Christian Watermann, Anna Dubrovska, Christian Idel, Jutta Kirfel, Andreas Schröck, Julika Ribbat-Idel
Publikováno v:
Clinical Cancer Research 27(2021), 632-644
Purpose: Recurrent tumors (RT) of head and neck squamous cell carcinoma (HNSCC) occur in up to 60%, with poor therapeutic response and detrimental prognosis. We hypothesized that HNSCC RTs successfully evade antitumor immune response and aimed to rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df44bc1f6b61d3b542d3f2d02b1b9d6
https://www.hzdr.de/publications/Publ-33979-1
https://www.hzdr.de/publications/Publ-33979-1
Autor:
Christian Watermann, Rosemarie Krupar, Christian Idel, Jutta Kirfel, Sven Perner, Helen Pasternack, Julika Ribbat-Idel, Anne Offermann, Andrew G. Sikora
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
The tumor immune microenvironment (TIME) of head and neck squamous cell carcinomas (HNSCC) and other solid malignancies is a key determinant of therapy response and prognosis. Among other factors, it is shaped by the tumor mutational burden and defec