Výsledky vyhledávání - "Christian W. Ehrenfels"

Perturbation of RET signaling in the embryonic kidney

Autor: Olivia Orozco, Richard L. Cate, Michele Sanicola, Christian W. Ehrenfels, Paul Carmillo

Publikováno v: Developmental Genetics. 24:263-272

We have used a RET-Ig fusion protein to disrupt signaling in the rat embryonic kidney development pathway. Treatment of embryonic kidney organ cultures with RET-Ig results in a decrease in branching of the ureteric bud and a down regulation in expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb0f36b5bba419fd8f35b49222683cb1
https://doi.org/10.1002/(sici)1520-6408(1999)24:3/4<263::aid-dvg9>3.0.co

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Processing of anti-mullerian hormone regulates receptor activation by a mechanism distinct from TGF-beta

Autor: Christian W. Ehrenfels, Nathalie Josso, Jean-Yves Picard, Paul Carmillo, Soazik P. Jamin, Nathalie di Clemente, R. Blake Pepinsky, Adrian Whitty, Alexey Lugovskoy, Richard L. Cate

Publikováno v: Molecular Endocrinology-Baltimore
Molecular Endocrinology-Baltimore-, Endocrine Society, 2010, 24 (11), pp.2193-206. ⟨10.1210/me.2010-0273⟩

TGF-β family ligands are translated as prepropeptide precursors and are processed into mature C-terminal dimers that signal by assembling a serine/threonine kinase receptor complex containing type I and II components. Many TGF-β ligands are secrete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4136e5f10b3e1c5fd5f77c76a810ee47
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01122137

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Genomic Southern analysis with alkaline-phosphatase-conjugated oligonucleotide probes and the chemiluminescent substrate AMPPD

Autor: Owen J. Murphy, Richard L. Cate, Irena Bronstein, Mark Wysk, Richard Tizard, John C. Voyta, Christian W. Ehrenfels

Publikováno v: Genetic Analysis: Biomolecular Engineering. 8:102-106

We have used a chemiluminescent detection method to improve both the sensitivity and the speed of detection of human genes with oligonucleotide probes. A direct chemiluminescent substrate (AMPPD) was used in combination with an alkaline-phosphatase-l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c875272c88edb642ad55268414e38b5
https://doi.org/10.1016/1050-3862(91)90044-r

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Mutations of the Anti-Müllerian Hormone Gene in Patients with Persistent Müllerian Duct Syndrome: Biosynthesis, Secretion, and Processing of the Abnormal Proteins and Analysis Using a Three-Dimensional Model

Autor: Alireza R. Rezaie, Nathalie di Clemente, Jean-Yves Picard, Richard L. Cate, Nathalie Josso, Corinne Belville, Christian W. Ehrenfels, Herman W. T. van Vlijmen, Pepinsky R Blake

Publikováno v: Molecular Endocrinology-Baltimore
Molecular Endocrinology-Baltimore-, Endocrine Society, 2004, 18 (3), pp.708-721. ⟨10.1210/me.2003-0358⟩
Molecular Endocrinology-Baltimore-, 2004, 18 (3), pp.708-721. ⟨10.1210/me.2003-0358⟩

International audience; Anti-Müllerian hormone (AMH), a TGF-beta family member, determines whether an individual develops a uterus and Fallopian tubes. Mutations in the AMH gene lead to persistent Müllerian duct syndrome in males. The wild-type hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd8ede2096021b43085f0b0cd4f48cb
https://hal.archives-ouvertes.fr/hal-01930675

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Detection of DNA in Southern Blots with Chemiluminescence

Autor: Richard Tizard, Christian W. Ehrenfels, Owen J. Murphy, Richard L. Cate, John C. Voyta, Irena Y. Bronstein

Publisher Summary The analysis of DNA by membrane hybridization techniques is important in the characterization of cloned genes, investigation of genetic diseases, detection of pathogens, forensic determinations, as well as many other areas of biolog

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https://doi.org/10.1016/b978-0-12-765561-1.50035-7

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List of Contributors

Autor: MARIE ALLEN, MICHELLE A. ALTING-MEES, FRANCISCO JOSÉ AYALA, SILVIA BÄHRING, ALAN T. BANKIER, BARCLAY G. BARRELL, STEVEN R. BAUER, STEPHAN BECK, MICHAEL BECKER-ANDRÉ, JEAN-PAUL BEHR, ASHOK S. BHAGWAT, ADI D. BHARUCHA, H.C. BIRNBOIM, CYNTHIA D.K. BOTTEMA, JOHAN BOTTERMAN, IRENA BRONSTEIN, CAROL M. BROWN, MICHAEL BULL, ZELING CAI, JOSLYN D. CASSADY, RICHARD L. CATE, KARL X. CHAI, JULIE CHAO, LEE CHAO, MARK S. CHEE, LIN CHEN, CHRISTOPHER COLECLOUGH, MOLLY CRAXTON, MARC DE BLOCK, SUSANA DE LA LUNA, JEFFREY R. DE WET, JÜRGEN DENECKE, KATHLEEN D'HALLUIN, ZIJIN DU, CHARYL M. DUTTON, V.J. DWARKI, JAMES EBERWINE, DAVID D. ECKELS, CHRISTIAN W. EHRENFELS, HENRY ERLICH, GLEN A. EVANS, GIOVANNA FERRO-LUZZI AMES, RICHARD FINNELL, MICHAEL A. FROHMAN, CARL W. FULLER, ODD S. GABRIELSEN, J. VICTOR GARCIA, MELISSA A. GEE, MARY JANE GEIGER, JACK GORSKI, TOM J. GUILFOYLE, ULF B. GYLLENSTEN, GRETCHEN HAGEN, MICHAEL K. HANAFEY, DANIEL L. HARTL, GARY G. HERMANSON, STEFFAN N. HO, LEROY HOOD, ROBERT M. HORTON, DENNIS E. HRUBY, JANINE HUET, TIM C. HUFFAKER, HENRY D. HUNT, SETSUKO II, JAN JANSSENS, MICHAEL D. JONES, VINCENT JUNG, ERNEST KAWASAKI, MARTIN KREITMAN, LAURA F. LANDWEBER, JAN LEEMANS, JEAN-CLAUDE LELONG, GEORGES LÉVESQUE, ANDRE LIEBER, JEAN-PHILIPPE LOEFFLER, KENNETH R. LUEHRSEN, CARMEL M. LYNCH, KURTIS D. MACFERRIN, SCOTT MACKLER, KAYO MAEDA, ROBERT W. MALONE, BRUCE A. MCCLURE, A. DUSTY MILLER, DANIEL G. MILLER, KEVIN MIYASHIRO, OWEN J. MURPHY, HOWARD OCHMAN, JUAN ORTÍU, GARY V. PADDOCK, R. PADMANABHAN, LARRY R. PEASE, SIDNEY PESTKA, STEVEN B. PESTKA, HUNTINGTON POTTER, ANNEMARIE POUSTKA, JEFFREY K. PULLEN, J. ANTONI RAFALSKI, WILLIAM D. RAWLINSON, ARLETTE REYNAERTS, J.A. RUSSELL, RANDALL SAIKI, VOLKER SANDIG, J.C. SANFORD, GOBINDA SARKAR, RICHARD H. SCHEUERMANN, STUART L. SCHREIBER, JAMIE K. SCOTT, GEORG SCZAKIEL, J.M. SHORT, VENKATAKRISHNA SHYAMALA, HARINDER SINGH, F.D. SMITH, GEORGE P. SMITH, VICTORIA SMITH, KEN SNIDER, JAEMOG SOH, WOLFGANG SOMMER, STEVE S. SOMMER, YAH-RU SONG, J.A. SORGE, CORINNE SPENCER, MICHAEL STRAUSS, KENNETH D. TARTOF, MICHAEL P. TERRANOVA, SCOTT V. TINGEY, RICHARD TIZARD, JOSEPH E. VARNER, M.R. VEN MURTHY, GREGORY L. VERDINE, INDER M. VERMA, JOHN C. VOYTA, VIRGINIA WALBOT, PAUL A. WHITTAKER, JOHN G.K. WILLIAMS, ELIZABETH M. WILSON, RICHARD K. WILSON, ZHENG-HUA YE, ANDREW D. ZELENETZ, Q.X. ZHANG, L.-J. ZHAO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f755e478655db98d729b9684a3a6e8ea
https://doi.org/10.1016/b978-0-12-765561-1.50004-7

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Mullerian inhibiting substance requires its N-terminal domain for maintenance of biological activity, a novel finding within the transforming growth factor-beta superfamily

Autor: Christian W. Ehrenfels, N Josso, R B Pepinsky, C A Wilson, N di Clemente, Richard L. Cate, B Vigier

Publikováno v: Molecular endocrinology (Baltimore, Md.). 7(2)

Mullerian inhibiting substance (MIS)/anti-Mullerian hormone is a differentiation factor that causes regression of the Mullerian duct in the developing male fetus and an apparent sex reversal of the fetal ovary when inappropriately exposed to it. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea903dd1035000aa4beeba9e06119dc
https://pubmed.ncbi.nlm.nih.gov/8469238

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[29] Detection of DNA in southern blots with chemiluminescence

Autor: Irena Bronstein, John C. Voyta, Owen J. Murphy, Richard L. Cate, Christian W. Ehrenfels, Richard Tizard

Publikováno v: Methods in Enzymology ISBN: 9780121821180

The chemiluminescent detection methods described in this chapter have been successfully applied to the detection of plasmid DNA and genomic DNA in Southern and sequencing protocols. The high sensitivity and the simplicity of AMPPD are instrumental in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d9cd24b8884670f19b7c2cb5b0840a2
https://doi.org/10.1016/0076-6879(93)17079-k

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Mutant expression of male copulatory bursa surface markers in Caenorhabditis elegans

Autor: Christopher D. Link, Christian W. Ehrenfels, William B. Wood

Publikováno v: Development (Cambridge, England). 103(3)

In a search for molecular markers of male tail morphogenesis in C. elegans, we have detected two surface markers that are specifically observed in the copulatory bursa of adult males and the vulva of adult hermaphrodites. These markers are defined by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce938fab2ac3c96ac10579515e2feba
https://pubmed.ncbi.nlm.nih.gov/3246219

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