Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Christian Vesin"'
Autor:
Rodolphe Dusaulcy, Sandra Handgraaf, Florian Visentin, Christian Vesin, Jacques Philippe, Yvan Gosmain
Publikováno v:
Molecular Metabolism, Vol 22, Iss , Pp 84-95 (2019)
Objective: Diabetes is a complex disease implicating several organs and cell types. Within the islets, dysregulation occurs in both alpha- and beta-cells, leading to defects of insulin secretion and increased glucagon secretion. Dysregulation of alph
Externí odkaz:
https://doaj.org/article/ce67e07ab81443eab99532b2b2bde786
Publikováno v:
Clinical and Developmental Immunology, Vol 8, Iss 3-4, Pp 183-191 (2001)
Externí odkaz:
https://doaj.org/article/a200f83a4a3c42c3b163f529b41547da
Autor:
Fiona M. Gribble, Jacques Philippe, Frank Reimann, Christian Vesin, Svetlana Skarupelova, Yvan Gosmain, Rodolphe Dusaulcy, Mounia Heddad-Masson, Sandra Handgraaf, Florian Visentin
Publikováno v:
Endocrinology
Endocrinology, Vol. 157, No 10 (2016) pp. 3832-3843
Endocrinology, Vol. 157, No 10 (2016) pp. 3832-3843
Glucose homeostasis depends on the coordinated secretion of glucagon, insulin, and Glucagon-like peptide (GLP)-1 by pancreas and intestine. Obesity, which is associated with an increased risk of developing insulin resistance and type 2 diabetes, affe
Autor:
Christian Vesin, Florian Visentin, Sandra Handgraaf, Rodolphe Dusaulcy, Yvan Gosmain, Jacques Philippe
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 22, Iss, Pp 84-95 (2019)
Molecular Metabolism, Vol 22, Iss, Pp 84-95 (2019)
Objective Diabetes is a complex disease implicating several organs and cell types. Within the islets, dysregulation occurs in both alpha- and beta-cells, leading to defects of insulin secretion and increased glucagon secretion. Dysregulation of alpha
Autor:
Dominique Talabot-Ayer, Christian Alexander Seemayer, Solenne Vigne, Gaby Palmer, Christian Vesin, Praxedis Martin, Cem Gabay
Publikováno v:
Journal of immunology (Baltimore Md. : 1950)
Journal of Immunology
Journal of Immunology, Vol. 194, No 2 (2015) pp. 750-60
Journal of Immunology
Journal of Immunology, Vol. 194, No 2 (2015) pp. 750-60
IL-33 is a cytokine of the IL-1 family, which signals through the ST2 receptor. Previous studies emphasized a role for IL-33 in shaping innate and adaptive immune responses. IL-33 was also reported to modulate myelopoiesis and myeloid cell activity.
Autor:
Gaby Palmer, Christian Vesin, Christian Alexander Seemayer, Laura Rubbia-Brandt, Céline Lamacchia, Cem Gabay, Emiliana Rodriguez
Publikováno v:
European Journal of Immunology. 42:1294-1303
Interleukin-1 receptor antagonist (IL-1Ra) is a specific IL-1 inhibitor that possesses anti-inflammatory activities. Several studies in human and mouse suggested a protective role for IL-1Ra in liver inflammation, and we previously demonstrated that
Autor:
Fiona M. Gribble, Sandra Handgraaf, Mounia Heddad-Masson, Yvan Gosmain, Florian Visentin, Rodolphe Dusaulcy, Jacques Philippe, Franck Reimann, Christian Vesin
Publikováno v:
Endocrinology
Endocrinology, Vol. 157, No 2 (2016) pp. 536-547
Endocrinology, Vol. 157, No 2 (2016) pp. 536-547
Glucagon and α-cell dysfunction are critical in the development of hyperglycemia during diabetes both in humans and rodents. We hypothesized that α-cell dysfunction leading to dysregulated glucagon secretion in diabetes is due to both a lack of ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c2dfb7062238fc27831fdfaaf8b548
https://europepmc.org/articles/PMC7228809/
https://europepmc.org/articles/PMC7228809/
Autor:
Michel Aurrand-Lions, Dominique Ducrest-Gay, Nathalie Busso, Dominique Talabot-Ayer, Cem Gabay, Gaby Palmer, Christian Vesin, Véronique Chobaz-Péclat, Emmanuel Contassot
Publikováno v:
The Journal of Immunology. 177:2899-2907
Leptin-deficient ob/ob and leptin receptor (Ob-rb)-deficient db/db mice display a marked thymic atrophy and exhibit defective immune responses. Lymphocytes express leptin receptors and leptin exerts direct effects on T cells in vitro. In addition, ob
Autor:
Pierre F. Piguet, Christian Vesin
Publikováno v:
European Journal of Haematology. 68:253-261
Anti-platelet antibodies are known to contribute to some types of thrombocytopenia. In this work we investigated anti-platelet antibodies with opposite influence upon activation and kinetics of platelet caspases. A rabbit anti-platelet antibody induc
Publikováno v:
European Journal of Cell Biology. 80:171-177
Summary We explored the role of CD18 (β2 integrin) in platelet physiology, using mice genetically deficient in CD18 (CD18 −/−), or its main ligand CD54 (ICAM-1, CD54 −/−). CD18 and CD11a were evident in platelets from +/+, but not from CD18