Zobrazeno 1 - 10
of 5 293
pro vyhledávání: '"Christian V"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 3785-3801 (2024)
Ferroptosis is a novel type of regulated cell death (RCD) involving iron accumulation and lipid peroxidation. Since its discovery in 2012, various studies have shown that ferroptosis is associated with the pathogenesis of various diseases. Ferroptoti
Externí odkaz:
https://doaj.org/article/1c8f89c5c23e4c1490ac5e48a28d5a0b
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Chemical engineers heavily rely on precise knowledge of physicochemical properties to model chemical processes. Despite the growing popularity of deep learning, it is only rarely applied for property prediction due to data scarcity and limit
Externí odkaz:
https://doaj.org/article/9405871e1d324eb99ff9cceb11dcd982
Publikováno v:
Earth's Future, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Tipping elements are features of the climate system that can display self‐reinforcing and non‐linear responses if pushed beyond a certain threshold (the “tipping point”). Models suggest that we may surpass several of these tipping po
Externí odkaz:
https://doaj.org/article/e2431ed91618471581fc82dae0b08a32
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract The challenge of devising pathways for organic synthesis remains a central issue in the field of medicinal chemistry. Over the span of six decades, computer-aided synthesis planning has given rise to a plethora of potent tools for formulatin
Externí odkaz:
https://doaj.org/article/b06ab84516ee4a91ba480235421339e2
Autor:
Sten P. Willemsen, Ronny Knol, Emma Brouwer, Thomas van den Akker, Philip L. J. DeKoninck, Enrico Lopriore, Wes Onland, Willem P. de Boode, Anton H. van Kaam, Debbie H. Nuytemans, Irwin K. M. Reiss, G. Jeroen Hutten, Sandra A. Prins, Estelle E. M. Mulder, Christian V. Hulzebos, Sam J. van Sambeeck, Mayke E. van der Putten, Inge A. Zonnenberg, Arjan B. te Pas, Marijn J. Vermeulen
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Mortality, cerebral injury, and necrotizing enterocolitis (NEC) are common complications of very preterm birth. An important risk factor for these complications is hemodynamic instability. Pre-clinical studies suggest that the tim
Externí odkaz:
https://doaj.org/article/8717f45925ef4abeba353f4147ec8526
Autor:
Michael J. Lavelle, Evangelia Kaza, Christian V. Guthier, Desmond A. O’Farrell, Thomas C. Harris, Robert A. Cormack, Phillip M. Devlin, Ivan M. Buzurovic
Publikováno v:
Journal of Contemporary Brachytherapy, Vol 16, Iss 1, Pp 48-56 (2024)
Externí odkaz:
https://doaj.org/article/d8f4d93dd89a49ee94ce9c8a67beb4eb
Autor:
Yujie Yan, Christopher Kehayias, John He, Hugo J. W. L. Aerts, Kelly J. Fitzgerald, Benjamin H. Kann, David E. Kozono, Christian V. Guthier, Raymond H. Mak
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Manual segmentation of tumors and organs-at-risk (OAR) in 3D imaging for radiation-therapy planning is time-consuming and subject to variation between different observers. Artificial intelligence (AI) can assist with segmentation, but challe
Externí odkaz:
https://doaj.org/article/0d3314f05d744208ab8a55d3f5e81d38
Autor:
Christian V. Recktenwald, Göran Karlsson, Maria-Jose Garcia-Bonete, Gergely Katona, Maja Jensen, Richard Lymer, Malin Bäckström, Malin E.V. Johansson, Gunnar C. Hansson, Sergio Trillo-Muyo
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114207- (2024)
Summary: The MUC2 mucin protects the colonic epithelium by a two-layered mucus with an inner attached bacteria-free layer and an outer layer harboring commensal bacteria. CysD domains are 100 amino-acid-long sequences containing 10 cysteines that sep
Externí odkaz:
https://doaj.org/article/9cf85ba6d78a4dee8ce486d5c3a77539
Autor:
Melike Pala, Martijn G. Castelein, Camille Dewaele, Sophie L. K. W. Roelants, Wim K. Soetaert, Christian V. Stevens
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Sophorolipids, glycolipid biosurfactants derived from microorganisms such as Starmerella bombicola, possess distinctive surface-active and bioactive properties, holding potential applications in cosmetics, pharmaceuticals and bioremediation. However,
Externí odkaz:
https://doaj.org/article/8af6a667de0c46f9a75853839b674b73
Autor:
Christopher E. Kehayias, Yujie Yan, Dennis Bontempi, Sarah Quirk, Danielle S. Bitterman, Jeremy S. Bredfeldt, Hugo J. W. L. Aerts, Raymond H. Mak, Christian V. Guthier
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
IntroductionArtificial intelligence (AI)-based technologies embody countless solutions in radiation oncology, yet translation of AI-assisted software tools to actual clinical environments remains unrealized. We present the Deep Learning On-Demand Ass
Externí odkaz:
https://doaj.org/article/621f368a4dfd488c9073e9f52498d7dc