Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Christian U. Oeing"'
Autor:
Jacopo Agrimi, Lucia Bernardele, Naeem Sbaiti, Marco Brondi, Donato D’Angelo, Marta Canato, Ivan Marchionni, Christian U. Oeing, Giussy Barbara, Beatrice Vignoli, Marco Canossa, Nina Kaludercic, Gaya Spolverato, Anna Raffaello, Claudia Lodovichi, Marco Dal Maschio, Nazareno Paolocci
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110585- (2024)
Summary: Intimate partner violence (IPV) is a significant public health concern whose neurological/behavioral sequelae remain to be mechanistically explained. Using a mouse model recapitulating an IPV scenario, we evaluated the female brain neuroendo
Externí odkaz:
https://doaj.org/article/34ad0784ee3643dc8f82539012cb8465
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Impaired or insufficient protein kinase G (PKG) signaling and protein quality control (PQC) are hallmarks of most forms of cardiac disease, including heart failure. Their dysregulation has been shown to contribute to and exacerbate cardiac hypertroph
Externí odkaz:
https://doaj.org/article/19a8023949f847a8881fa112f52a3645
Autor:
Michaela Schäfer, Christian U. Oeing, Maria Rohm, Ezgi Baysal-Temel, Lorenz H. Lehmann, Ralf Bauer, H. Christian Volz, Michael Boutros, Daniela Sohn, Carsten Sticht, Norbert Gretz, Katrin Eichelbaum, Tessa Werner, Marc N. Hirt, Thomas Eschenhagen, Karin Müller-Decker, Oliver Strobel, Thilo Hackert, Jeroen Krijgsveld, Hugo A. Katus, Mauricio Berriel Diaz, Johannes Backs, Stephan Herzig
Publikováno v:
Molecular Metabolism, Vol 35, Iss , Pp - (2020)
Externí odkaz:
https://doaj.org/article/ea76deb615ca4c0d9e6c97a62a0ed7ec
Autor:
David Bode, Lukas Semmler, Christian U. Oeing, Alessio Alogna, Gabriele G. Schiattarella, Burkert M. Pieske, Frank R. Heinzel, Felix Hohendanner
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5937 (2021)
Atrial fibrillation (AF) is the most common sustained (atrial) arrhythmia, a considerable global health burden and often associated with heart failure. Perturbations of redox signalling in cardiomyocytes provide a cellular substrate for the manifesta
Externí odkaz:
https://doaj.org/article/8cda5727d23040e6908a3cf5daa4f572
Autor:
Michaela Schäfer, Christian U. Oeing, Maria Rohm, Ezgi Baysal-Temel, Lorenz H. Lehmann, Ralf Bauer, H. Christian Volz, Michael Boutros, Daniela Sohn, Carsten Sticht, Norbert Gretz, Katrin Eichelbaum, Tessa Werner, Marc N. Hirt, Thomas Eschenhagen, Karin Müller-Decker, Oliver Strobel, Thilo Hackert, Jeroen Krijgsveld, Hugo A. Katus, Mauricio Berriel Diaz, Johannes Backs, Stephan Herzig
Publikováno v:
Molecular Metabolism, Vol 5, Iss 2, Pp 67-78 (2016)
Objectives: Cancer cachexia affects the majority of tumor patients and significantly contributes to high mortality rates in these subjects. Despite its clinical importance, the identity of tumor-borne signals and their impact on specific peripheral o
Externí odkaz:
https://doaj.org/article/b5837ba8229f44a0ac946a52d475155d
Autor:
Christian U. Oeing, Mark E. Pepin, Kerstin B. Saul, Ayça Seyhan Agircan, Yassen Assenov, Tobias S. Merkel, Farbod Sedaghat-Hamedani, Tanja Weis, Benjamin Meder, Kaomei Guan, Christoph Plass, Dieter Weichenhan, Dominik Siede, Johannes Backs
Publikováno v:
Basic Research in Cardiology. 118
Precision-based molecular phenotyping of heart failure must overcome limited access to cardiac tissue. Although epigenetic alterations have been found to underlie pathological cardiac gene dysregulation, the clinical utility of myocardial epigenomics
Autor:
Nicole Taube, Nazareno Paolocci, Ana M. Rule, Obialunanma V Ebenebe, Rui Chen, Raihan Kabir, Sumita Mishra, Mark J. Kohr, Prithvi Sinha, Christian U. Oeing, Gizem Keceli
Publikováno v:
Am J Physiol Heart Circ Physiol
Arsenic exposure though drinking water is widespread and well associated with adverse cardiovascular outcomes, yet the pathophysiological mechanisms by which iAS induces these effects are largely unknown. Recently, an epidemiological study in an Amer
Autor:
Nazareno Paolocci, Brittany Dunkerly-Eyring, Seungho Jun, Usman A. Tahir, Christian U. Oeing, Mark J. Ranek, Sumita Mishra, Robert E. Gerszten, Anna Chen, David A. Kass, Maria I. Grajeda
Publikováno v:
Circulation Research. 128:639-651
Rationale: The mTORC1 (mechanistic target of rapamycin complex-1) controls metabolism and protein homeostasis and is activated following ischemia reperfusion (IR) injury and by ischemic preconditioning (IPC). However, studies vary as to whether this
Autor:
Brittany Dunkerly-Eyring, Sean Murphy, Dorothy D. Sears, Vivek Jani, Christian U. Oeing, Deepthi Ashok, Sumita Mishra, Nandhini Sadagopan, Ryan P. Ceddia, Jon A. Gangoiti, Hildur Knutsdottir, Dylan C. Sarver, Susana Rodriguez, Brian O'Rourke, Sheila Collins, David A. Kass, G. William Wong
Publikováno v:
The Journal of clinical investigation, vol 131, iss 21
J Clin Invest
J Clin Invest
Central obesity with cardiometabolic syndrome (CMS) is a major global contributor to human disease, and effective therapies are needed. Here, we show inhibiting cyclic-GMP selective phosphodiesterase-9A (PDE9-I) in both ovariectomized female or male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eecce43b1dec62ad1470f66350bc8ca4
https://escholarship.org/uc/item/0dd5m0g8
https://escholarship.org/uc/item/0dd5m0g8
Autor:
Pinilla-Vera M, Sumita Mishra, Christian U. Oeing, Mark J. Ranek, McKoy D, Grajeda Martinez Mi, Brittany Dunkerly-Eyring, David A. Kass
SummaryThe mammalian target of rapamycin complex 1 (mTORC1) is tightly controlled by tuberous sclerosis complex-2 (TSC2) that is regulated by phosphorylation from kinases responding to environmental cues. Protein kinase G specifically modifies serine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7627158eb5eb290a9eb683a46499f093
https://doi.org/10.1101/2021.07.13.452249
https://doi.org/10.1101/2021.07.13.452249