Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christian T. Straub"'
Autor:
Howard M. Stern, Christian T. Straub, Leonard I. Zon, James F. Amatruda, Gerhard J. Weber, Ryan D. Murphey, John A. Tallarico, Kathleen L. Pfaff, Randall W. King, Jennifer L. Shepard
Publikováno v:
Nature Chemical Biology. 1:366-370
Bmyb is a ubiquitously expressed transcription factor involved in cellular proliferation and cancer. Loss of bmyb function in the zebrafish mutant crash&burn (crb) results in decreased cyclin B1 expression, mitotic arrest and genome instability. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0133930fd77a318e91867123b1654e7b
https://doi.org/10.1038/nchembio749
https://doi.org/10.1038/nchembio749
Publikováno v:
Molecular and cellular biology. 27(16)
A critical step in cell division is formation of the mitotic spindle, which is a bipolar array of microtubules that mediates chromosome separation. Here, we report that the SCL-interrupting locus (SIL), a vertebrate-specific cytosolic protein, is nec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7504e657890a9a4174c139a07d796f4e
https://pubmed.ncbi.nlm.nih.gov/17576815
https://pubmed.ncbi.nlm.nih.gov/17576815
Publikováno v:
Chemical biologydrug design. 68(4)
Chemical genetic screening is an effective strategy to identify compounds that alter a specific biological phenotype. As a complement to cell line screens, multicellular organism screens may reveal additional compounds. The zebrafish embryo is ideal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea9d9c96e954f4e7888367ab9ceea19
https://pubmed.ncbi.nlm.nih.gov/17105485
https://pubmed.ncbi.nlm.nih.gov/17105485