Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Christian T Carson"'
Autor:
Gene W Yeo, Xiangdong Xu, Tiffany Y Liang, Alysson R Muotri, Christian T Carson, Nicole G Coufal, Fred H Gage
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 10, Pp 1951-1967 (2007)
Human embryonic stem cells (hESCs) and neural progenitor (NP) cells are excellent models for recapitulating early neuronal development in vitro, and are key to establishing strategies for the treatment of degenerative disorders. While much effort had
Externí odkaz:
https://doaj.org/article/24b182a2e8a24c499670e239a31ce42c
Autor:
Kumar Sukhdeo, Rosanto I Paramban, Jason G Vidal, Jeanne Elia, Jody Martin, Maricruz Rivera, Daniel R Carrasco, Awad Jarrar, Matthew F Kalady, Christian T Carson, Robert Balderas, Anita B Hjelmeland, Justin D Lathia, Jeremy N Rich
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53015 (2013)
Colon cancer is a deadly disease affecting millions of people worldwide. Current treatment challenges include management of disease burden as well as improvements in detection and targeting of tumor cells. To identify disease state-specific surface a
Externí odkaz:
https://doaj.org/article/0983840af68e467da6cc6db6bf17e1d9
Autor:
Sivan Harel, Edmund Y Tu, Stuart Weisberg, Manuel Esquilin, Stuart M Chambers, Becky Liu, Christian T Carson, Lorenz Studer, Boris Reizis, Mark J Tomishima
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42302 (2012)
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) offer great promise in regenerative medicine and disease modeling due to their unlimited self-renewal and broad differentiation capacity. There is evidence that the growth propert
Externí odkaz:
https://doaj.org/article/392618b4656a4f26bb7abe9144d80fa9
Autor:
Shauna H Yuan, Jody Martin, Jeanne Elia, Jessica Flippin, Rosanto I Paramban, Mike P Hefferan, Jason G Vidal, Yangling Mu, Rhiannon L Killian, Mason A Israel, Nil Emre, Silvia Marsala, Martin Marsala, Fred H Gage, Lawrence S B Goldstein, Christian T Carson
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17540 (2011)
Neural induction of human pluripotent stem cells often yields heterogeneous cell populations that can hamper quantitative and comparative analyses. There is a need for improved differentiation and enrichment procedures that generate highly pure popul
Externí odkaz:
https://doaj.org/article/b56b0088093f4d5f81634553f591aa8c
Autor:
Nil Emre, Jason G Vidal, Jeanne Elia, Eric D O'Connor, Rosanto I Paramban, Michael P Hefferan, Roman Navarro, Danielle S Goldberg, Nissi M Varki, Martin Marsala, Christian T Carson
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12148 (2010)
BACKGROUND: Due to the inherent sensitivity of human embryonic stem cells (hESCs) to manipulations, the recovery and survival of hESCs after fluorescence-activated cell sorting (FACS) can be low. Additionally, a well characterized and robust methodol
Externí odkaz:
https://doaj.org/article/0b00a564d7024862aaa6ab4596dfd96d
Autor:
Nil Emre, Jeffrey M. Hegarty, Kirk U. Knowlton, Alec D. Witty, Canzhao Liu, Dekker C. Deacon, Kelly A. Frazer, Jason G. Vidal, Elie Farah, Karina Palomares, Sylvia M. Evans, Mirko Corselli, Christian T. Carson, Patrick van Vliet, Maggie Zhu, Ralf J. Dirschinger, Eric Adler, Jennifer Veevers, Kunfu Ouyang, Jonathan D. Grinstein, Neil C. Chi, Ju Chen, Jody Martin
Publikováno v:
Stem cell reports, vol 11, iss 3
Stem Cell Reports, Vol 11, Iss 3, Pp 828-841 (2018)
Stem Cell Reports, Vol 11, Iss 3, Pp 828-841 (2018)
Summary: To facilitate understanding of human cardiomyocyte (CM) subtype specification, and the study of ventricular CM biology in particular, we developed a broadly applicable strategy for enrichment of ventricular cardiomyocytes (VCMs) derived from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f29c4e6d6759c66d97ccf51ddd6fffd
https://doi.org/10.1016/j.stemcr.2018.07.007
https://doi.org/10.1016/j.stemcr.2018.07.007
Autor:
Ernest M. Meyer, Albert D. Donnenberg, Jayce Jieming Zhang, Vera S. Donnenberg, Haihui Lu, Christian T. Carson, Erika Moravcikova
Publikováno v:
Cytometry Part A. 93:448-457
Flow cytometric cell surface proteomics provides a new and powerful tool to determine changes accompanying neoplastic transformation and invasion, providing clues to essential interactions with the microenvironment as well as leads for potential ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5baa1ec0f18cb66c221ea01e7f2125
https://doi.org/10.1002/cyto.a.23300
https://doi.org/10.1002/cyto.a.23300
Autor:
Sassan Keshavarzi, Shauna H. Yuan, Ján Gálik, S. van Gorp, Marjolein Leerink, Stefan Juhas, Joseph D. Ciacci, Christian T. Carson, Jason G. Vidal, Jana Juhasova, Michael P. Hefferan, Peter Lazar, Atsushi Miyanohara, Danielle Goldberg, Osamu Kakinohana, Silvia Marsala, Martin Marsala, Jan Motlik, Oleksandr Platoshyn
Publikováno v:
Cell Transplantation, Vol 21 (2012)
In previous studies, we have demonstrated that spinal grafting of human or rat fetal spinal neural precursors leads to amelioration of spasticity and improvement in ambulatory function in rats with spinal ischemic injury. In the current study, we cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4fbb9a402b9fbe8623a8590d608e9f2
https://doi.org/10.3727/096368912x653200
https://doi.org/10.3727/096368912x653200
Autor:
Sol M. Reyna, Francesca S. Boscolo, Louise C. Laurent, Anne M. Remes, Sebastiaan van Gorp, Edward H. Koo, Shauna H. Yuan, Lawrence S.B. Goldstein, Michael P. Hefferan, Fred H. Gage, Yangling Mu, Kristopher L. Nazor, Christian T. Carson, Cheryl Herrera, Martin Marsala, Mason A. Israel, Cedric Bardy
Publikováno v:
Nature, vol 482, iss 7384
Nature
Nature, 482(7384), 216-U107. Nature Publishing Group
Nature
Nature, 482(7384), 216-U107. Nature Publishing Group
Our understanding of Alzheimer's disease pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model the sporadic form of the disease. It may be possible to overcome these challenges by reprogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a3617eda8a5a98af794ec45819b01e
https://cris.maastrichtuniversity.nl/en/publications/e4430046-ba7d-4be8-8f05-4f841ba7f10a
https://cris.maastrichtuniversity.nl/en/publications/e4430046-ba7d-4be8-8f05-4f841ba7f10a
Autor:
Christian T. Carson, Darwin V. Lee, Jiri Lukas, Matthew D. Weitzman, Nicole I. Orazio, Seema S. Lakdawala, Caroline E. Lilley, Jiri Bartek, Junghae Suh, Felipe D. Araujo, Simon Bekker-Jensen
Publikováno v:
The EMBO Journal. 28:652-662
The protein kinases ataxia-telangiectasia mutated (ATM) and ATM-Rad3 related (ATR) are activated in response to DNA damage, genotoxic stress and virus infections. Here we show that during infection with wild-type adenovirus, ATR and its cofactors RPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e72dc1a5b0d96adbf044a7e683d355
https://doi.org/10.1038/emboj.2009.15
https://doi.org/10.1038/emboj.2009.15