Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christian Supan"'
Autor:
Jana Held, Christian Supan, Carmen L. Ospina Salazar, Halidou Tinto, Léa Nadège Bonkian, Alain Nahum, Ali Sié, Salim Abdulla, Cathy Cantalloube, Elhadj Djeriou, Marielle Bouyou-Akotet, Bernhards Ogutu, Benjamin Mordmüller, Andrea Kreidenweiss, Mohamadou Siribie, Sodiomon B. Sirima, Peter G. Kremsner
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-12 (2017)
Abstract Background Malaria remains one of the most important infectious diseases. Treatment options for severe malaria are limited and the choline analogue SAR97276A is a novel chemical entity that was developed primarily as treatment for severe mal
Externí odkaz:
https://doaj.org/article/ef1036a672254739b5714c7719ed185b
Autor:
Cantalloube C, Bernhards Ogutu, Otsula N, Peter G. Kremsner, Apollo D, Walsh Ds, Elhadj Djeriou, Christian Supan, Ghyslain Mombo-Ngoma, John N. Waitumbi, Mark E. Polhemus, Bertrand Lell, Ospina Salazar Cl, Maryvonne Kombila, Jana Held
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 97:514-525
Artemisinin-based combination therapies are recommended as first-line agents for treating uncomplicated Plasmodium falciparum malaria. Ferroquine, a 4-aminoquinolone, is a novel long-acting combination partner for fast-acting drugs like artesunate (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190a3698fb7436eff546231f74cbb659
https://doi.org/10.4269/ajtmh.16-0731
https://doi.org/10.4269/ajtmh.16-0731
Autor:
Serena Tschan, Sandra Dimonte, Peter G. Kremsner, Matthias Flötenmeyer, Carmen L. Ospina Salazar, Jürgen Berger, Benjamin Mordmüller, Betty Kim Lee Sim, Iris Koch, Jana Held, Christian Supan, Ellen Bruske, Johanna Hass, Matthias Frank, Stephen L. Hoffman, Meral Esen, Anna Bachmann
Publikováno v:
Journal of Infectious Diseases. 214:884-894
Background. Antigenic variation in Plasmodium falciparum is mediated by the multicopy var gene family. Each parasite possesses about 60 var genes, and switching between active var loci results in antigenic variation. In the current study, the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1339762b5525e58fb8163752793c7f81
https://doi.org/10.1093/infdis/jiw225
https://doi.org/10.1093/infdis/jiw225
Autor:
Chantal Din-Bell, Jana Held, Ali Sié, Carmen L. Ospina Salazar, Sodiomon B. Sirima, Alain Nahum, Léa Nadège Bonkian, Nekoye Otsyula, Lucas Otieno, Ahmed M Abdallah, Peter G. Kremsner, Bertrand Lell, Bancole Moulero, Robert Kimutai, Kimiko Koiwai, Mohamadou Siribié, Elhadj Djeriou, Cathy Cantalloube, Benjamin Mordmüller, Maryvonne Kombila, Marielle K. Bouyou-Akotet, Christian Supan, Daniel Ter-Minassian, Halidou Tinto, John N. Waitumbi, Boubacar Coulibaly
Publikováno v:
The Lancet Infectious Diseases. 15:1409-1419
Summary Background Artemisinin-based combination therapies (ACTs) are the recommended first-line treatment for uncomplicated Plasmodium falciparum malaria. Ferroquine is a new combination partner for fast-acting ACTs such as artesunate. We aimed to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f0670e21fe687311ae1c2979ef20bc
https://doi.org/10.1016/s1473-3099(15)00079-1
https://doi.org/10.1016/s1473-3099(15)00079-1
Autor:
Peter G. Kremsner, Michael Ramharter, Saadou Issifou, Christophe Biot, Aziz Filali-Ansary, Ghyslain Mombo-Ngoma, Carmen L. Ospina Salazar, Matthias P. Dal-Bianco, Florent Mazuir, Bertrand Lell, Christian Supan, Daniel Ter-Minassian
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:3165-3173
Ferroquine (SSR97193), a ferrocene-quinoline conjugate, is a promising novel antimalarial currently undergoing clinical evaluation. This study characterizes its pharmacokinetic properties. Young male African volunteers with asymptomatic Plasmodium fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9856a1a794064101803603a4ece9d043
https://doi.org/10.1128/aac.05359-11
https://doi.org/10.1128/aac.05359-11
Autor:
Saadou Issifou, Christian Supan, Matthias P. Dal-Bianco, Peter G. Kremsner, Michel A. Missinou, Ghyslain Mombo Ngoma, Bertrand Lell, Kai B. Köster, Ulrich D. Kombila, Pierre Blaise Matsiegui, Carmen L. Ospina Salazar, Jürgen F. J. Kun, Martin P. Grobusch
Publikováno v:
American journal of tropical medicine and hygiene, 77(5), 939-942. American Society of Tropical Medicine and Hygiene
Plasmodium falciparum, the most common malarial parasite in sub-Saharan Africa, accounts for a high number of deaths in children less than five years of age. In malaria-endemic countries with stable transmission, semi-immunity is usually acquired aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ee8083e8292a0cfb29b359bd9199cb
https://doi.org/10.4269/ajtmh.2007.77.939
https://doi.org/10.4269/ajtmh.2007.77.939
Autor:
Michael Ramharter, Pierre-Blaise Matsiegui, Bertrand Lell, Peter G. Kremsner, Matthias P. Dal-Bianco, Ghyslain Mombo-Ngoma, Christian Supan, Carmen L. Ospina Salazar, Michel A. Missinou, Daniel Ter-Minassian, Maryvonne Kombila, Saadou Issifou
Publikováno v:
Malaria Journal, Vol 10, Iss 1, p 53 (2011)
Malaria Journal
Malaria Journal
Background The development and spread of drug resistant Plasmodium falciparum strains is a major concern and novel anti-malarial drugs are, therefore, needed. Ferroquine is a ferrocenic derivative of chloroquine with proven anti-malarial activity aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e4a43f21cd9fbe298d58fe19f9b3c6
https://doi.org/10.1186/1475-2875-10-53
https://doi.org/10.1186/1475-2875-10-53
Autor:
Ghyslain Mombo Ngoma, Matthias P. Dal-Bianco, Martin P. Grobusch, Nicola Lehners, Pembe Issamou Mayengue, Klaus Dietz, Julian J. Gabor, Francine Ntoumi, Peter G. Kremsner, David U Kombila, Bertrand Lell, Matthias Frank, Christian Supan
Publikováno v:
Malaria Journal, 10(1). BioMed Central
Malaria Journal, Vol 10, Iss 1, p 304 (2011)
Malaria Journal
Malaria journal, 10(1). BioMed Central
Malaria Journal, Vol 10, Iss 1, p 304 (2011)
Malaria Journal
Malaria journal, 10(1). BioMed Central
Background Chloroquine resistance (CR) decreased after the removal of chloroquine from national treatment guidelines in Malawi, Kenia and Tanzania. In this investigation the prevalence of the chloroquine resistance (CQR) conferring mutant pfcrt allel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04533f7053e3f4b92714ebb9d08c197
https://dare.uva.nl/personal/pure/en/publications/a-thirteenyear-analysis-of-plasmodium-falciparum-populations-reveals-high-conservation-of-the-mutant-pfcrt-haplotype-despite-the-withdrawal-of-chloroquine-from-national-treatment-guidelines-in-gabon(ddbaa454-0952-4c78-89bf-e0d1dd689040).html
https://dare.uva.nl/personal/pure/en/publications/a-thirteenyear-analysis-of-plasmodium-falciparum-populations-reveals-high-conservation-of-the-mutant-pfcrt-haplotype-despite-the-withdrawal-of-chloroquine-from-national-treatment-guidelines-in-gabon(ddbaa454-0952-4c78-89bf-e0d1dd689040).html
Autor:
Matthias P, Dal-Bianco, Kai B, Köster, Ulrich D, Kombila, Jürgen F J, Kun, Martin P, Grobusch, Ghyslain Mombo, Ngoma, Pierre B, Matsiegui, Christian, Supan, Carmen L Ospina, Salazar, Michel A, Missinou, Saadou, Issifou, Bertrand, Lell, Peter, Kremsner
Publikováno v:
The American journal of tropical medicine and hygiene. 77(5)
Plasmodium falciparum, the most common malarial parasite in sub-Saharan Africa, accounts for a high number of deaths in children less than five years of age. In malaria-endemic countries with stable transmission, semi-immunity is usually acquired aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72c2dec33a6c4928cf67488806aab83a
https://pubmed.ncbi.nlm.nih.gov/17984357
https://pubmed.ncbi.nlm.nih.gov/17984357
Autor:
Martin P. Grobusch, Peter G. Kremsner, Kai B. Köster, Jenny Dornemann, Peter Pongratz, Julian J. Gabor, Bertrand Lell, Georg Kiessling, Benjamin Naumann, Magdalena Necek, Julia Goesch, Christian Supan, Selidji T Agnandji, Isabelle von Glasenapp, Matthias Längin, Peter M. C. Klein Klouwenberg, Marie-Luise Decker, Davy U Kombila, Carmen L. Ospina Salazar, Lea B. Borchert, Norbert Georg Schwarz, A.A. Adegnika, Handan Altun, Saadou Issifou, Sunny Oyakhirome, Marc Pötschke, Anna Klöpfer
Publikováno v:
Journal of infectious diseases, 196(11), 1595-1602. Oxford University Press
BACKGROUND: Intermittent preventive treatment aims to maximize the protective effects of malaria chemoprophylaxis while minimizing the deleterious effects. METHODS: In Gabon, 1189 infants received either sulfadoxine-pyrimethamine (SP; 250 and 12.5 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29857fae59f20ca422c5ede667ebdfa9
https://pubmed.ncbi.nlm.nih.gov/18008242
https://pubmed.ncbi.nlm.nih.gov/18008242