Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christian Sundberg"'
Autor:
Jakob Karén, Alejandro Rodriguez, Tomas Friman, Lennart Dencker, Christian Sundberg, Birger Scholz
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24954 (2011)
Microvascular pericytes are of key importance in neoformation of blood vessels, in stabilization of newly formed vessels as well as maintenance of angiostasis in resting tissues. Furthermore, pericytes are capable of differentiating into pro-fibrotic
Externí odkaz:
https://doaj.org/article/8077904b187547388e02e5df0ee2a833
Autor:
Christian Sundberg
Publikováno v:
Proceedings of the 39th IAHR World Congress.
Publikováno v:
The American Journal of Pathology. 175:171-189
How activation of a specific growth factor receptor selectively results in either cell proliferation or cytoskeletal reorganization is of central importance to the field of pathophysiology. In this study, we report on a novel mechanism that explains
Autor:
Bengt Gerdin, Alejandro Rodriguez, Kristofer Rubin, Humphrey Gardner, Christian Sundberg, Jakob Karén
Publikováno v:
Journal of Cellular and Molecular Medicine
Connective tissue cell activation is of importance during reactive conditions such as solid tumour growth, wound healing and pannus formation in rheumatoid arthritis. Here, we have compared connective tissue cells of mesenchymal origin in human tissu
Autor:
Kristofer Rubin, Christian Sundberg, Nils-Erik Heldin, Pernilla Roswall, Humphrey Gardner, Alexei V. Salnikov
Publikováno v:
Laboratory Investigation. 85:512-521
A pathologically elevated interstitial fluid pressure (IFP) is a characteristic of both clinical and experimental carcinoma. The soluble TGF-beta receptor type II-murine Fc:IgG2A chimeric protein (Fc:TbetaRII) lowers IFP in the KAT-4 experimental mod
Autor:
Lars Rask, Göran Hjälm, Robert Robinson, Åke Engström, Erik G. Larsson, Amos M. Sakwe, Anna Stina Höglund, Christian Sundberg, Mårten Larsson
Publikováno v:
Biochemical Journal. 373:381-391
Megalin is an integral membrane receptor belonging to the low-density lipoprotein receptor family. In addition to its role as an endocytotic receptor, megalin has also been proposed to have signalling functions. Using interaction cloning in yeast, we
Autor:
Christian Sundberg, Ellen Lammerts, Alexei V. Salnikov, Nils-Erik Heldin, Annica Jacobson, Kristofer Rubin, Pernilla Roswall, Paraskevi Heldin
Publikováno v:
Biochemical and Biophysical Research Communications. 305:1017-1023
Mechanism(s) for generation of the high tumor interstitial fluid pressure (TIFP) that is characteristic of carcinoma is not known. We investigated the role of hyaluronan, the major water-binding polysaccharide of the extracellular matrix, for the gen
Autor:
Xiaolian Tan, Janice A. Nagy, Dian Feng, Eliza Vasile, Ann M. Dvorak, Christian Sundberg, Harold F. Dvorak, Michael Detmar, Joel A. Lawitts, Laura E. Benjamin, Eleanor J. Manseau, Lawrence F. Brown
Publikováno v:
The Journal of Experimental Medicine
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF, VEGF-A) is a multifunctional cytokine with important roles in pathological angiogenesis. Using an adenoviral vector engineered to express murine VEGF-A164, we previously inves
Autor:
Eleanor J. Manseau, Christian Sundberg, Harold F. Dvorak, Ann M. Dvorak, Eliza Vasile, Dian Feng, Janice A. Nagy, Lawrence F. Brown
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 67:227-238
Autor:
Isabelle A. Eckelhoefer, Dian Feng, Ann M. Dvorak, Christian Sundberg, Harold F. Dvorak, Lawrence F. Brown, Eleanor J. Manseau, Janice A. Nagy
Publikováno v:
The American Journal of Pathology. 158:1145-1160
Glomeruloid bodies are a defining histological feature of glioblastoma multiforme and some other tumors and vascular malformations. Little is known about their pathogenesis. We injected a nonreplicating adenoviral vector engineered to express vascula