Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christian Staat"'
Autor:
Philipp Berndt, Lars Winkler, Ingolf E. Blasig, Anneliese Krüger, Jimmi Cording, Basak Arslan, Ramona Günther, Susanne M. Krug, Reiner F. Haseloff, Christian Staat, Sophie Dithmer
Publikováno v:
Annals of the New York Academy of Sciences. 1405:89-101
The majority of tight junction (TJ) proteins restrict the paracellular permeation of solutes via their extracellular loops (ECLs). Tricellulin tightens tricellular TJs (tTJs) and regulates bicellular TJ (bTJ) proteins. We demonstrate that the additio
Autor:
Thoralf Niendorf, Ingolf E. Blasig, Nora Gehne, Andreas Pohlmann, Petra Fallier-Becker, Mária A. Deli, Lars Winkler, Christian Staat, Fruzsina R. Walter, Min Chi Ku, Ágnes Kittel, Rosel Blasig, Reiner F. Haseloff, Szilvia Veszelka, Sophie Dithmer, Carolin Müller
Publikováno v:
Annals of the New York Academy of Sciences. 1397:169-184
The blood–brain barrier (BBB) formed by the microvascular endothelium limits cerebral drug delivery. The paraendothelial cleft is sealed by tight junctions (TJs) with a major contribution from claudin-5, which we selected as a target to modulate BB
Publikováno v:
JCMS: Journal of Common Market Studies. 55:368-386
Parliamentarians are often allowed to pursue other work in addition to their mandate. Using data on the 7th European Parliament (2009–14), we analyze the relationship between the outside earnings of its Members (MEPs) and their parliamentary activi
Publikováno v:
European Economic Review. 85:8-21
Previous work on informed-principal problems with moral hazard suggested that the principal should signal project quality by retaining a larger share of the project and hence lowering incentives for the agent. We show that this view is incomplete. If
Autor:
Jimmi, Cording, Basak, Arslan, Christian, Staat, Sophie, Dithmer, Susanne M, Krug, Anneliese, Krüger, Philipp, Berndt, Ramona, Günther, Lars, Winkler, Ingolf E, Blasig, Reiner F, Haseloff
Publikováno v:
Annals of the New York Academy of Sciences. 1405(1)
The majority of tight junction (TJ) proteins restrict the paracellular permeation of solutes via their extracellular loops (ECLs). Tricellulin tightens tricellular TJs (tTJs) and regulates bicellular TJ (bTJ) proteins. We demonstrate that the additio
Autor:
Sophie, Dithmer, Christian, Staat, Carolin, Müller, Min-Chi, Ku, Andreas, Pohlmann, Thoralf, Niendorf, Nora, Gehne, Petra, Fallier-Becker, Ágnes, Kittel, Fruzsina R, Walter, Szilvia, Veszelka, Maria A, Deli, Rosel, Blasig, Reiner F, Haseloff, Ingolf E, Blasig, Lars, Winkler
Publikováno v:
Annals of the New York Academy of Sciences. 1397(1)
The blood-brain barrier (BBB) formed by the microvascular endothelium limits cerebral drug delivery. The paraendothelial cleft is sealed by tight junctions (TJs) with a major contribution from claudin-5, which we selected as a target to modulate BBB
Publikováno v:
Annals of the New York Academy of Sciences. 1257:29-37
Claudin proteins are involved in the paracellular tightening of epithelia and endothelia. Their internalization, which can be modulated by extracellular stimuli, for example, proinflammatory cytokines, is a prerequisite for the regulation of the para
Autor:
H.L. Rittner, Ingolf E. Blasig, Alexander Böcker, Christian Staat, Dagmar Hackel, Alexander Brack, Michael Beyermann, Denise Zwanziger
Publikováno v:
Molecular Pharmaceutics. 9:1785-1794
The paracellular flux of solutes through tissue barriers is limited by transmembrane tight junction proteins. Within the family of tight junction proteins, claudin-1 seems to be a key protein for tightness formation and integrity. In the peripheral n
Autor:
Reiner F. Haseloff, Denise Zwanziger, Heike L. Rittner, Christian Bellmann, Ingolf E. Blasig, Ramona Günther, Reine-Solange Sauer, Eberhard Krause, Christian Staat, Sebastian Dabrowski
Publikováno v:
Antioxidants & redox signaling, 22(1): 1-14
The paracellular cleft within epithelia/endothelia is sealed by tight junction (TJ) proteins. Their extracellular loops (ECLs) are assumed to control paracellular permeability and are targets of pathogenes. We demonstrated that claudin-1 is crucial f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faabd6dc9aefa86e6f9b31ad2706fa03
https://europepmc.org/articles/PMC4270150/
https://europepmc.org/articles/PMC4270150/
Autor:
Britta Engelhardt, Svetlana M. Stamatovic, Christian Staat, Caroline Coisne, Sebastian Dabrowski, Hartwig Wolburg, Anuska V. Andjelkovic, Ingolf E. Blasig
Publikováno v:
Biomaterials. 54
In epithelial/endothelial barriers, claudins form tight junctions, seal the paracellular cleft, and limit the uptake of solutes and drugs. The peptidomimetic C1C2 from the C-terminal half of claudin-1's first extracellular loop increases drug deliver