Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christian Sigl"'
Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein
Autor:
Oskar Staufer, Kapil Gupta, Jochen Estebano Hernandez Bücher, Fabian Kohler, Christian Sigl, Gunjita Singh, Kate Vasileiou, Ana Yagüe Relimpio, Meline Macher, Sebastian Fabritz, Hendrik Dietz, Elisabetta Ada Cavalcanti Adam, Christiane Schaffitzel, Alessia Ruggieri, Ilia Platzman, Imre Berger, Joachim P. Spatz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Staufer et al. provide a protocol for preparation of synthetic minimal virions (MiniV) of SARS-CoV-2, mimicking viral structure and allowing for precise investigation of receptor binding mechanism. They find that the highly conserved free fatty acid
Externí odkaz:
https://doaj.org/article/6ea4469e431243f488c82533fd47c2d8
Autor:
Christian Sigl, Hendrik Dietz
Publikováno v:
BIOspektrum. 28:165-167
The current pandemic has highlighted the need for new antiviral therapies, to respond to existing and emerging diseases transmitted by viral vectors. We developed a novel antiviral approach that is based on neutralizing viruses by trapping and encaps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e125b9550f478c07d6315a93bdf91f3
https://doi.org/10.1007/s12268-022-1729-2
https://doi.org/10.1007/s12268-022-1729-2
Autor:
Daichi Hayakawa, Thomas E. Videbaek, Douglas M. Hall, Huang Fang, Christian Sigl, Elija Feigl, Hendrik Dietz, Seth Fraden, Michael F. Hagan, Gregory M. Grason, W. Benjamin Rogers
Self-assembly is one of the most promising strategies for making functional materials at the nanoscale, yet new design principles for making self-limiting architectures, rather than spatially unlimited periodic lattice structures, are needed. To addr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f735072bda4c1c736120b99925acc3
Autor:
Alba Monferrer, Fabian Kohler, Christian Sigl, Michael Schachtner, David Peterhoff, Benedikt Asbach, Ralf Wagner, Hendrik Dietz
Publikováno v:
Cell Reports Physical Science. 4:101237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36620de25abe05002c2fcfd73cff8ccf
https://doi.org/10.1016/j.xcrp.2022.101237
https://doi.org/10.1016/j.xcrp.2022.101237
Publikováno v:
Nature. 552:78-83
By using DNA sequence information to encode the shapes of DNA origami building blocks, shape-programmable assemblies can be created, with sizes and complexities similar to those of viruses. In nature, large and complex structures such as viruses asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131ec5a9787827f776a402b490ff1949
https://doi.org/10.1038/nature24651
https://doi.org/10.1038/nature24651
Publikováno v:
Biophysical Journal. 112:474a-475a
Large and discrete biological assemblies such as the flagellar motor or viral capsids form by hierarchical self-assembly of many different protein subunits where some of these subunits often occur in multiple copies. For assemblies such as capsids th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c30e4428427b3777f415d0dfab85d175
https://doi.org/10.1016/j.bpj.2016.11.2548
https://doi.org/10.1016/j.bpj.2016.11.2548