Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Christian Sieben"'
Autor:
Lea Gabele, Isabell Bochow, Nele Rieke, Christian Sieben, Kristin Michaelsen-Preusse, Shirin Hosseini, Martin Korte
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Influenza A virus (IAV) infection can increase the risk of neuroinflammation, and subsequent neurodegenerative diseases. Certain IAV strains, such as avian H7N7 subtype, possess neurotropic properties, enabling them to directly invade the brain paren
Externí odkaz:
https://doaj.org/article/70707ffabe6246fc9d7ada9f0b6349ac
Autor:
Ivo M. Glück, Grusha Primal Mathias, Sebastian Strauss, Virgile Rat, Irene Gialdini, Thomas Sebastian Ebert, Che Stafford, Ganesh Agam, Suliana Manley, Veit Hornung, Ralf Jungmann, Christian Sieben, Don C. Lamb
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108382- (2023)
Summary: The NLRP3 inflammasome is a central component of the innate immune system. Its activation leads to formation of the ASC speck, a supramolecular assembly of the inflammasome adaptor protein ASC. Different models, based on ASC overexpression,
Externí odkaz:
https://doaj.org/article/f518dcc0b67d43c7ba16f7aa2b31c012
Autor:
Laura Menke, Christian Sieben
Publikováno v:
Viruses, Vol 16, Iss 2, p 269 (2024)
Determination of the infectious titer is a central requirement when working with pathogenic viruses. The plaque or focus assay is a commonly used but labor- and time-consuming approach for determining the infectious titer of orthohantavirus samples.
Externí odkaz:
https://doaj.org/article/d44edb3d3f774f428d05b80dae426a15
Autor:
Markus Kastner, Andreas Karner, Rong Zhu, Qiang Huang, Andreas Geissner, Anne Sadewasser, Markus Lesch, Xenia Wörmann, Alexander Karlas, Peter H. Seeberger, Thorsten Wolff, Peter Hinterdorfer, Andreas Herrmann, Christian Sieben
Publikováno v:
Viruses, Vol 15, Iss 7, p 1507 (2023)
Influenza A viruses (IAVs) initiate infection via binding of the viral hemagglutinin (HA) to sialylated glycans on host cells. HA’s receptor specificity towards individual glycans is well studied and clearly critical for virus infection, but the co
Externí odkaz:
https://doaj.org/article/1ae2a970a61c4f8eb500c10316c51fb6
Autor:
Bryan Wang, Yu-Cheng Lin, Alejandro Vasquez-Rifo, Jeanyoung Jo, Alexa Price-Whelan, Shujuan Tao McDonald, Lewis M. Brown, Christian Sieben, Lars E. P. Dietrich
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
R-bodies are long, extendable protein polymers formed in the cytoplasm of some bacteria. Here, Wang et al. show that Pseudomonas aeruginosa produces R-bodies during colonization of plant and nematode hosts, and R-bodies induce ribosome cleavage and t
Externí odkaz:
https://doaj.org/article/e62ad031b3894821b3d96bbb38aba300
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2021)
Understanding the structure of a protein complex is crucial in determining its function. However, retrieving accurate 3D structures from microscopy images is highly challenging, particularly as many imaging modalities are two-dimensional. Recent adva
Externí odkaz:
https://doaj.org/article/3ac8918c9b5544deb4a522cd179b9b3c
Autor:
Anna Archetti, Evgenii Glushkov, Christian Sieben, Anton Stroganov, Aleksandra Radenovic, Suliana Manley
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample hold
Externí odkaz:
https://doaj.org/article/cfceec778eb841798554c99bdf6ae604
Autor:
Marco Kirchenwitz, Stephanie Stahnke, Silvia Prettin, Malgorzata Borowiak, Laura Menke, Christian Sieben, Carmen Birchmeier, Klemens Rottner, Theresia E. B. Stradal, Anika Steffen
Publikováno v:
Cells, Vol 11, Iss 10, p 1648 (2022)
SMER28 (Small molecule enhancer of Rapamycin 28) is an autophagy-inducing compound functioning by a hitherto unknown mechanism. Here, we confirm its autophagy-inducing effect by assessing classical autophagy-related parameters. Interestingly, we also
Externí odkaz:
https://doaj.org/article/2a8ee43ec6084ff5a40865674077a6a2
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008656 (2020)
Influenza A virus (IAV) binds its host cell using the major viral surface protein hemagglutinin (HA). HA recognizes sialic acid, a plasma membrane glycan that functions as the specific primary attachment factor (AF). Since sialic acid alone cannot fu
Externí odkaz:
https://doaj.org/article/8bc7ae06315e450aa5a8b7d8543e69b4
Autor:
Robert-William Welke, Hannah Sabeth Sperber, Ronny Bergmann, Amit Koikkarah, Laura Menke, Christian Sieben, Detlev H. Krüger, Salvatore Chiantia, Andreas Herrmann, Roland Schwarzer
Publikováno v:
Viruses, Vol 14, Iss 3, p 457 (2022)
Hantaviruses are enveloped viruses that possess a tri-segmented, negative-sense RNA genome. The viral S-segment encodes the multifunctional nucleocapsid protein (N), which is involved in genome packaging, intracellular protein transport, immunoregula
Externí odkaz:
https://doaj.org/article/e3d399b345e347d190ea0b523cd2c36a