Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Christian Schmeer"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
BackgroundThe pathomechanisms underlying migraine are intricate and remain largely unclear. Initially regarded as a neuronal disorder, migraine research primarily concentrated on understanding the pathophysiological changes within neurons. However, r
Externí odkaz:
https://doaj.org/article/c88bde8f6e284d7f8015877d139a8a01
Autor:
Annette Brandt, Anja Baumann, Angélica Hernández-Arriaga, Finn Jung, Anika Nier, Raphaela Staltner, Dragana Rajcic, Christian Schmeer, Otto W. Witte, Barbara Wessner, Bernhard Franzke, Karl-Heinz Wagner, Amélia Camarinha-Silva, Ina Bergheim
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102528- (2022)
Aging is considered a state of low grade inflammation, occurring in the absence of any overt infection often referred to as ‘inflammaging'. Maintaining intestinal homeostasis may be a target to extend a healthier status in older adults. Here, we re
Externí odkaz:
https://doaj.org/article/ac4f6005d1e241ec9238e14648355c8d
Autor:
Trim Lajqi, Milan Stojiljkovic, David L. Williams, Hannes Hudalla, Michael Bauer, Otto W. Witte, Reinhard Wetzker, Reinhard Bauer, Christian Schmeer
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Microglia, the innate immune cells of the central nervous system, feature adaptive immune memory with implications for brain homeostasis and pathologies. However, factors involved in the emergence and regulation of these opposing responses in microgl
Externí odkaz:
https://doaj.org/article/ad30f515b9904494a238b75de085c28a
Autor:
Diana M. Morales-Prieto, José M. Murrieta-Coxca, Milan Stojiljkovic, Celia Diezel, Priska E. Streicher, Julian A. Henao-Restrepo, Franziska Röstel, Julia Lindner, Otto W. Witte, Sebastian Weis, Christian Schmeer, Manja Marz
Publikováno v:
Cells, Vol 11, Iss 4, p 625 (2022)
Extracellular vesicles (EVs), including small EVs (sEVs), are involved in neuroinflammation and neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. Yet, increased neuroinflammation ca
Externí odkaz:
https://doaj.org/article/eb0080699fc34f6dabdd934a792677e4
Publikováno v:
Cells, Vol 8, Iss 11, p 1446 (2019)
In contrast to the programmed nature of development, it is still a matter of debate whether aging is an adaptive and regulated process, or merely a consequence arising from a stochastic accumulation of harmful events that culminate in a global state
Externí odkaz:
https://doaj.org/article/2dd2afabe03e4ea7b920a2b2f05ab5d0
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 2, Pp 421-430 (2006)
Heat shock proteins (Hsps) are stress proteins that mediate protein stabilization in various tissues and protect cells from environmental stress. Novel evidence suggests that overexpression of the small heat shock protein 27 (Hsp27) in neurons protec
Externí odkaz:
https://doaj.org/article/aed871ee94a14296a1543c540871dafe
Autor:
Ertugrul Kilic, Dirk M. Hermann, Sebastian Kügler, ;Ülkan Kilic, Harry Holzmüller, Christian Schmeer, Mathias Bähr
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 2, Pp 275-284 (2002)
The effects of an adenovirus-mediated Bcl-XL expression, driven by a neuron-specific human synapsin-1 promoter, on the degree of injury, were examined after transient focal ischemia in mice. Therefore, injections of vehicle, of an adenoviral E1-delet
Externí odkaz:
https://doaj.org/article/6651e9d911f048ff90c201f224ca657e
Autor:
Guido Straten, Christian Schmeer, Alexandra Kretz, Ellen Gerhardt, Sebastian Kügler, Jörg B. Schulz, Claude Gravel, Mathias Bähr, Stefan Isenmann
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 1, Pp 123-133 (2002)
Following transection of the optic nerve (ON) in the adult rat, retinal ganglion cells (RGCs) undergo degeneration, and within 14 days 85% of axotomized RGCs die by apoptosis. Adenoviral delivery of the mammalian caspase inhibitor X-chromosome-linked
Externí odkaz:
https://doaj.org/article/f54dbb76051244d1b560be297a2bf8da
Autor:
Marianne Hege, Anna Janina Engstler, Annika Höhn, Richard Kehm, Cheng Jun Jin, Otto W. Witte, Annette Brandt, Anika Nier, Christian Schmeer, Anja Baumann, Ina Bergheim, Tilman Grune
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 318:G736-G747
Aging is a risk factor in the development of many diseases, including liver-related diseases. The two aims of the present study were 1) to determine how aging affects liver health in mice in the absence of any interventions and 2) if degenerations ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e62c968c1bcd4e8f3dad45d8f458ac
https://doi.org/10.1152/ajpgi.00345.2018
https://doi.org/10.1152/ajpgi.00345.2018
Autor:
Marz, Diana M. Morales-Prieto, José M. Murrieta-Coxca, Milan Stojiljkovic, Celia Diezel, Priska E. Streicher, Julian A. Henao-Restrepo, Franziska Röstel, Julia Lindner, Otto W. Witte, Sebastian Weis, Christian Schmeer, Manja
Publikováno v:
Cells; Volume 11; Issue 4; Pages: 625
Extracellular vesicles (EVs), including small EVs (sEVs), are involved in neuroinflammation and neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. Yet, increased neuroinflammation ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::317d43924f86ff4dedaa9017fefa2a58