Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christian SM Helker"'
Autor:
Jialing Qi, Annegret Rittershaus, Rashmi Priya, Shivani Mansingh, Didier YR Stainier, Christian SM Helker
Publikováno v:
eLife, Vol 11 (2022)
During cardiac development, endocardial cells (EdCs) produce growth factors to promote myocardial morphogenesis and growth. In particular, EdCs produce neuregulin which is required for ventricular cardiomyocytes (CMs) to seed the multicellular ridges
Externí odkaz:
https://doaj.org/article/561ad569dfef442eaa4544db02cc0211
Autor:
Claudio Andrés Carril Pardo, Laura Massoz, Marie A Dupont, David Bergemann, Jordane Bourdouxhe, Arnaud Lavergne, Estefania Tarifeño-Saldivia, Christian SM Helker, Didier YR Stainier, Bernard Peers, Marianne M Voz, Isabelle Manfroid
Publikováno v:
eLife, Vol 11 (2022)
Restoring damaged β-cells in diabetic patients by harnessing the plasticity of other pancreatic cells raises the questions of the efficiency of the process and of the functionality of the new Insulin-expressing cells. To overcome the weak regenerati
Externí odkaz:
https://doaj.org/article/ed76abafc69046b3bf95acc3dae8bee5
Autor:
Giulia LM Boezio, Anabela Bensimon-Brito, Janett Piesker, Stefan Guenther, Christian SM Helker, Didier YR Stainier
Publikováno v:
eLife, Vol 9 (2020)
The development of the cardiac outflow tract (OFT), which connects the heart to the great arteries, relies on a complex crosstalk between endothelial (ECs) and smooth muscle (SMCs) cells. Defects in OFT development can lead to severe malformations, i
Externí odkaz:
https://doaj.org/article/ac3d4d015b8440a6b7f28b7a53c86b4f
Autor:
Christian SM Helker, Jean Eberlein, Kerstin Wilhelm, Toshiya Sugino, Julian Malchow, Annika Schuermann, Stefan Baumeister, Hyouk-Bum Kwon, Hans-Martin Maischein, Michael Potente, Wiebke Herzog, Didier YR Stainier
Publikováno v:
eLife, Vol 9 (2020)
To form new blood vessels (angiogenesis), endothelial cells (ECs) must be activated and acquire highly migratory and proliferative phenotypes. However, the molecular mechanisms that govern these processes are incompletely understood. Here, we show th
Externí odkaz:
https://doaj.org/article/a7756ce122b04439b2b330f101fbb2e6
Autor:
Jean Eberlein, Lukas Herdt, Julian Malchow, Annegret Rittershaus, Stefan Baumeister, Christian SM Helker
Publikováno v:
Life, Vol 11, Iss 10, p 1088 (2021)
The establishment of a functional cardiovascular system is crucial for the development of all vertebrates. Defects in the development of the cardiovascular system lead to cardiovascular diseases, which are among the top 10 causes of death worldwide.
Externí odkaz:
https://doaj.org/article/64bebfa08b3e42de8eaba3a7115a0dfa
Autor:
Sri Teja Mullapudi, Christian SM Helker, Giulia LM Boezio, Hans-Martin Maischein, Anna M Sokol, Stefan Guenther, Hiroki Matsuda, Stefan Kubicek, Johannes Graumann, Yu Hsuan Carol Yang, Didier YR Stainier
Publikováno v:
eLife, Vol 7 (2018)
Pathways modulating glucose homeostasis independently of insulin would open new avenues to combat insulin resistance and diabetes. Here, we report the establishment, characterization, and use of a vertebrate ‘insulin-free’ model to identify insul
Externí odkaz:
https://doaj.org/article/2fc3b7c72300444894d22e3784775243
Autor:
Ryota L Matsuoka, Michele Marass, Avdesh Avdesh, Christian SM Helker, Hans-Martin Maischein, Ann S Grosse, Harmandeep Kaur, Nathan D Lawson, Wiebke Herzog, Didier YR Stainier
Publikováno v:
eLife, Vol 5 (2016)
Vascular networks surrounding individual organs are important for their development, maintenance, and function; however, how these networks are assembled remains poorly understood. Here we show that CNS progenitors, referred to as radial glia, modula
Externí odkaz:
https://doaj.org/article/1e58fcdc1ced422e83652512f7cbad98
Autor:
Marie A Dupont, Laura Massoz, Claudio Andrés Carril Pardo, David Bergemann, Jordane Bourdouxhe, Arnaud Lavergne, Estefania Tarifeño-Saldivia, Christian SM Helker, Didier YR Stainier, Bernard Peers, Marianne M Voz, Isabelle Manfroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f524c23ec48eaa5af31ebc4033cb8384
https://doi.org/10.7554/elife.67576.sa2
https://doi.org/10.7554/elife.67576.sa2
Autor:
Marie A Dupont, Laura Massoz, Claudio Andrés Carril Pardo, David Bergemann, Jordane Bourdouxhe, Arnaud Lavergne, Estefania Tarifeño-Saldivia, Christian SM Helker, Didier YR Stainier, Bernard Peers, Marianne M Voz, Isabelle Manfroid
Publikováno v:
eLife, Vol 11 (2022)
Restoring damaged β-cells in diabetic patients by harnessing the plasticity of other pancreatic cells raises the questions of the efficiency of the process and of the functionality of the new Insulin-expressing cells. To overcome the weak regenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83e8595ad639504bb3db76b52dcac83
https://elifesciences.org/articles/67576
https://elifesciences.org/articles/67576