Zobrazeno 1 - 10
of 18 617
pro vyhledávání: '"Christian S"'
Autor:
Jonathan Hira, Bhupender Singh, Tirthankar Halder, Anel Mahmutovic, Clement Ajayi, Arif Ahmed Sekh, Kristin Hegstad, Mona Johannessen, Christian S. Lentz
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Isogenic bacterial cell populations are phenotypically heterogenous and may include subpopulations of antibiotic tolerant or heteroresistant cells. The reversibility of these phenotypes and lack of biomarkers to differentiate functionally di
Externí odkaz:
https://doaj.org/article/9d5a74d86c664f9bb3e433fe6344da1e
Autor:
Anna K. Koch, Marleen Schröter, Julia Berschick, Julia K. Schiele, Martin Bogdanski, Melanie Steinmetz, Wiebke Stritter, Andreas Voss, Georg Seifert, Christian S. Kessler
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Healthcare professionals in hospitals are exposed to a high level of professional stress, time pressure, workload, and often times poor organizational support. This makes them especially susceptible to burnout. In this pragmatic r
Externí odkaz:
https://doaj.org/article/e6ee16dc2bf94740ba244e315aa04a7c
Autor:
Sirazul Haque, Miguel Alexandre, António T. Vicente, Kezheng Li, Christian S. Schuster, Sui Yang, Hugo Águas, Rodrigo Martins, Rute A. S. Ferreira, Manuel J. Mendes
Publikováno v:
Light: Science & Applications, Vol 13, Iss 1, Pp 1-13 (2024)
Abstract Advanced light management techniques can enhance the sunlight absorption of perovskite solar cells (PSCs). When located at the front, they may act as a UV barrier, which is paramount for protecting the perovskite layer against UV-enabled deg
Externí odkaz:
https://doaj.org/article/b86091c6192a495dbdea206d27ac48e5
Autor:
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Cesar Augusto Roque-Borda, Giulia Polinário, Rufo A. Figueroa Banda, Rafael Miguel Sábio, Marlus Chorilli, Hélder A. Santos, Fernando Rogério Pavan
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 106-134 (2024)
Tuberculosis (TB), caused by Mycobacterium tuberculosis, continues to pose a significant threat to global health. The resilience of TB is amplified by a myriad of physical, biological, and biopharmaceutical barriers that challenge conventional therap
Externí odkaz:
https://doaj.org/article/ef0782f017fe4af983b6ef947251c528
Autor:
Michael Pigula, Yen-Chung Lai, Minseob Koh, Christian S. Diercks, Thomas F. Rogers, David A. Dik, Peter G. Schultz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Live vaccines are ideal for inducing immunity but suffer from the need to attenuate their pathogenicity or replication to preclude the possibility of escape. Unnatural amino acids (UAAs) provide a strategy to engineer stringent auxotrophies,
Externí odkaz:
https://doaj.org/article/87101dc62f0641c78ed8f77a20954a87
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Cryopyrin-associated periodic syndromes (CAPS) are orphan hereditary auto-inflammatory diseases with various phenotypes, including chronic kidney disease (CKD). Current therapies inhibit interleukin-1 (IL-1) to achieve clinical and serologic
Externí odkaz:
https://doaj.org/article/347a47ff0dfc460c838a5fc516c0e003
Autor:
Devin P. Effinger, Jessica L. Hoffman, Sarah E. Mott, Sarah N. Magee, Sema G. Quadir, Christian S. Rollison, Daniel Toedt, Maria Echeveste Sanchez, Margaret W. High, Clyde W. Hodge, Melissa A. Herman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Psychedelics have experienced renewed interest following positive clinical effects, however the neurobiological mechanisms underlying effects remain unclear. The paraventricular nucleus of the hypothalamus (PVN) plays an integral role in str
Externí odkaz:
https://doaj.org/article/5c9edec683a641259bc478837e518a8c
Autor:
Sofie Falkenløve Madsen, Sarah Spliid Madsen, Alexander Scheller Madrid, Mikkel Rathsach Andersen, Anne-Christine Bay-Jensen, Christian S. Thudium
Publikováno v:
Translational Medicine Communications, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Background We aimed to investigate the development of synovial fibrosis in vitro and how the fibrosis can be halted. Synovial fibrosis causes joint stiffness in arthritic diseases. The pathway of the fibrotic growth factor, transforming grow
Externí odkaz:
https://doaj.org/article/5891c057397349e08699b0e2b5ee9800
Autor:
Xiang Zhou, Patrick Costello, Anita Schmitt, Carsten Müller-Tidow, Peter Dreger, Michael Schmitt, Max Topp, Hartmut Goldschmidt, Hermann Einsele, Nikhil C Munshi, Marc S Raab, Joseph Kauer, Thomas Hielscher, Niels Weinhold, Mirco J Friedrich, Sandra Sauer, Leo Rasche, Thomas Luft, Jan H Frenking, Vivien Wagner, Elias K Mai, Christian S Michel, Marina Hajiyianni, Iris Breitkreutz, Omar Nadeem, Adam S Sperling
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background Chimeric antigen receptor (CAR) T-cell therapy has demonstrated significant benefits in the treatment of relapsed/refractory multiple myeloma (RRMM). However, these outcomes can be compromised by severe complications, including cytokine re
Externí odkaz:
https://doaj.org/article/8940433ced884d68a993840e8bd1f4cb
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT The dCas9-based Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) interference (CRISPRi) gene regulation technique requires two components: a catalytically inactive Cas9 protein (dCas9) and a single-guide RNA that targets th
Externí odkaz:
https://doaj.org/article/79c63e1951bd4912b43c3f8b5913f8a5