Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Christian Roumestand"'
Autor:
Mounia Lahfa, Philippe Barthe, Karine de Guillen, Stella Cesari, Mouna Raji, Thomas Kroj, Marie Le Naour-Vernet, François Hoh, Pierre Gladieux, Christian Roumestand, Jérôme Gracy, Nathalie Declerck, André Padilla
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012176 (2024)
Magnaporthe AVRs and ToxB-like (MAX) effectors constitute a family of secreted virulence proteins in the fungus Pyricularia oryzae (syn. Magnaporthe oryzae), which causes blast disease on numerous cereals and grasses. In spite of high sequence diverg
Externí odkaz:
https://doaj.org/article/05ba20d0e9b1499aaf7604f2e1ef2251
Autor:
Mounia Lahfa, Assia Mouhand, Karine de Guillen, Philippe Barthe, Thomas Kroj, André Padilla, Christian Roumestand
Publikováno v:
Molecules, Vol 28, Iss 16, p 6068 (2023)
Does a similar 3D structure mean a similar folding pathway? This question is particularly meaningful when it concerns proteins sharing a similar 3D structure, but low sequence identity or homology. MAX effectors secreted by the phytopathogenic fungus
Externí odkaz:
https://doaj.org/article/4c4e5950cfbc46a188bf10f7ec703668
Autor:
Robert J. Noble, Viola Walther, Christian Roumestand, Michael E. Hochberg, Urszula Hibner, Patrice Lassus
Publikováno v:
Frontiers in Ecology and Evolution, Vol 9 (2021)
Explaining the emergence and maintenance of intratumor heterogeneity is an important question in cancer biology. Tumor cells can generate considerable subclonal diversity, which influences tumor growth rate, treatment resistance, and metastasis, yet
Externí odkaz:
https://doaj.org/article/f49cf3321ef847b0a531a171088e8739
Autor:
Antonino Caliò, Cécile Dubois, Stéphane Fontanay, Michael Marek Koza, François Hoh, Christian Roumestand, Philippe Oger, Judith Peters
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8469 (2022)
Life is thought to have appeared in the depth of the sea under high hydrostatic pressure. Nowadays, it is known that the deep biosphere hosts a myriad of life forms thriving under high-pressure conditions. However, the evolutionary mechanisms leading
Externí odkaz:
https://doaj.org/article/381389cfa5524c778c3608f9f2e914a4
Autor:
Cécile Dubois, Mounia Lahfa, Joana Pissarra, Karine de Guillen, Philippe Barthe, Thomas Kroj, Christian Roumestand, André Padilla
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5461 (2022)
Despite advances in experimental and computational methods, the mechanisms by which an unstructured polypeptide chain regains its unique three-dimensional structure remains one of the main puzzling questions in biology. Single-molecule techniques, ul
Externí odkaz:
https://doaj.org/article/1f5ba1f0d73740cd8a2e973cbf565ece
Autor:
Vincent Van Deuren, Yin-Shan Yang, Karine de Guillen, Cécile Dubois, Catherine Anne Royer, Christian Roumestand, Philippe Barthe
Publikováno v:
Biology, Vol 10, Iss 7, p 656 (2021)
Multidimensional NMR intrinsically provides multiple probes that can be used for deciphering the folding pathways of proteins: NH amide and CαHα groups are strategically located on the backbone of the protein, while CH3 groups, on the side-chain of
Externí odkaz:
https://doaj.org/article/459a9ae8186847b59c9d0e8f13a152f5
Autor:
Cécile Dubois, Vicente J. Planelles-Herrero, Camille Tillatte-Tripodi, Stéphane Delbecq, Léa Mammri, Elena M. Sirkia, Virginie Ropars, Christian Roumestand, Philippe Barthe
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3597 (2021)
When combined with NMR spectroscopy, high hydrostatic pressure is an alternative perturbation method used to destabilize globular proteins that has proven to be particularly well suited for exploring the unfolding energy landscape of small single-dom
Externí odkaz:
https://doaj.org/article/daee2a44d9d748b88f733c7658436d8a
Publikováno v:
Molecules, Vol 25, Iss 23, p 5551 (2020)
High-hydrostatic pressure is an alternative perturbation method that can be used to destabilize globular proteins. Generally perfectly reversible, pressure exerts local effects on regions or domains of a protein containing internal voids, contrary to
Externí odkaz:
https://doaj.org/article/fe3b1ddb97aa4941a8e36f50e6022d5c
Autor:
Tomonori Saotome, Maxime Doret, Manjiri Kulkarni, Yin-Shan Yang, Philippe Barthe, Yutaka Kuroda, Christian Roumestand
Publikováno v:
Biomolecules, Vol 9, Iss 8, p 309 (2019)
Dengue fever is a mosquito-borne endemic disease in tropical and subtropical regions, causing a significant public health problem in Southeast Asia. Domain III (ED3) of the viral envelope protein contains the two dominant putative epitopes and part o
Externí odkaz:
https://doaj.org/article/8174b50c65734b0e87da34ca818b28fb
Autor:
Virginie Ropars, Gilles Despouy, Marc-Henri Stern, Serge Benichou, Christian Roumestand, Stefan T Arold
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6567 (2009)
The T cell leukaemia/lymphoma 1A (TCL1A) oncoprotein plays key roles in several B and T cell malignancies. Lacking enzymatic activity, TCL1A's transforming action was linked to its capacity to co-activate the protein kinase AKT via binding to its ple
Externí odkaz:
https://doaj.org/article/7d4b5717a52e4914b5b4b05fba8d09ec