Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Christian Rosenberger"'
Autor:
Vicky Heß, Mumtaz Kasim, Susanne Mathia, Pontis B. Persson, Christian Rosenberger, Michael Fähling
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 5, Pp 1075-1091 (2019)
Externí odkaz:
https://doaj.org/article/bda4964176504287978a53397938f898
Autor:
Lutz Renders, Klemens Budde, Christian Rosenberger, Rachel van Swelm, Dorine Swinkels, Frank Dellanna, Werner Feuerer, Ming Wen, Christiane Erley, Birgit Bader, Claudia Sommerer, Matthias Schaier, Karoline Meurer, Louis Matis
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212023 (2019)
In chronic kidney disease both renal insufficiency and chronic inflammation trigger elevated hepcidin levels, which impairs iron uptake, availability. and erythropoiesis. Here we report the two first-in-human phase 1 trials of PRS-080#22, a novel, ra
Externí odkaz:
https://doaj.org/article/936377bd297b46aa88a277ec34cc06df
Autor:
Ruth E Schietke, Thomas Hackenbeck, Maxine Tran, Regina Günther, Bernd Klanke, Christina L Warnecke, Karl X Knaup, Deepa Shukla, Christian Rosenberger, Robert Koesters, Sebastian Bachmann, Peter Betz, Gunnar Schley, Johannes Schödel, Carsten Willam, Thomas Winkler, Kerstin Amann, Kai-Uwe Eckardt, Patrick Maxwell, Michael S Wiesener
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e31034 (2012)
The Hypoxia-inducible transcription Factor (HIF) represents an important adaptive mechanism under hypoxia, whereas sustained activation may also have deleterious effects. HIF activity is determined by the oxygen regulated α-subunits HIF-1α or HIF-2
Externí odkaz:
https://doaj.org/article/cf57eedd2a284375914bfd92fcd3be7f
Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens.
Autor:
Nadine Werth, Christiane Beerlage, Christian Rosenberger, Amir S Yazdi, Markus Edelmann, Amro Amr, Wanja Bernhardt, Christof von Eiff, Karsten Becker, Andrea Schäfer, Andreas Peschel, Volkhard A J Kempf
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11576 (2010)
BACKGROUND: Hypoxia inducible factor (HIF)-1 is the key transcriptional factor involved in the adaptation process of cells and organisms to hypoxia. Recent findings suggest that HIF-1 plays also a crucial role in inflammatory and infectious diseases.
Externí odkaz:
https://doaj.org/article/aa3fdf8ba14f421cafbf9f1e986ea066
Autor:
Robert Labes, Lennart Brinkmann, Vera A. Kulow, Kameliya Roegner, Susanne Mathia, Björn Balcerek, Pontus B. Persson, Christian Rosenberger, Michael Fähling
Publikováno v:
Kidney International. 102:750-765
Chronic Cyclosporine-A treatment is associated with serious side effects, including kidney toxicity and anemia. Although pathophysiology of Cyclosporine-A-induced kidney injury remains incompletely understood, hypoxia is likely involved. Here, we inv
Autor:
Tobias Sieckmann, Gunnar Schley, Neslihan Ögel, Simon Kelterborn, Felix J. Boivin, Michael Fähling, Muhammad I. Ashraf, Martin Reichel, Emilia Vigolo, Andrea Hartner, Falk-Bach Lichtenberger, Tilman Breiderhoff, Felix Knauf, Christian Rosenberger, Felix Aigner, Kai Schmidt-Ott, Holger Scholz, Karin M. Kirschner
Publikováno v:
Kidney International.
Autor:
Tobias Sieckmann, Neslihan Ögel, Simon Kelterborn, Felix J. Boivin, Gunnar Schley, Michael Fähling, Muhammad imtiaz Ashraf, Martin Reichel, Emilia Vigolo, Andrea Hartner, Felix Knauf, Christian Rosenberger, Felix Aigner, Kai Smidt‐Ott, Holger Scholz, Karin M. Kirschner
Publikováno v:
The FASEB Journal. 36
Autor:
Christian Rosenberger
Publikováno v:
Kidney international. 101(4)
Class 3 semaphorins (SEMA3) are secreted glycoproteins with established roles in the developing brain, heart, and kidney. In this issue of Kidney International, Cai et al. show that in acutely injured kidneys, semaphorin isoform SEMA3C is expressed d
Autor:
Kai-Uwe Eckardt, Christian Rosenberger
Publikováno v:
Seminars in Nephrology. 39:554-566
Although kidney oxygen tensions are heterogenous, and mostly below renal vein level, the nephron is highly dependent on aerobic metabolism for active tubular transport. This renders the kidney particularly susceptible to hypoxia, which is considered
Autor:
Susanne Mathia, Mumtaz Kasim, Vicky Heß, Pontus B. Persson, Michael Fähling, Christian Rosenberger
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 5, Pp 1075-1091 (2019)
BACKGROUND/AIMS Recently, we have demonstrated that episodic hypoxia occurs in kidneys of mice challenged repetitively with the immunosuppressant cyclosporine A (CsA), in analogy to humans on CsA treatment. However, the molecular consequences of epis