Zobrazeno 1 - 10
of 514
pro vyhledávání: '"Christian Rolfo"'
Autor:
Ander Puyalto, María Rodríguez-Remírez, Inés López, Irati Macaya, Elizabeth Guruceaga, María Olmedo, Anna Vilalta-Lacarra, Connor Welch, Sergio Sandiego, Silvestre Vicent, Karmele Valencia, Alfonso Calvo, Ruben Pio, Luis E. Raez, Christian Rolfo, Daniel Ajona, Ignacio Gil-Bazo
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background The identification of novel therapeutic strategies to overcome resistance to the MEK inhibitor trametinib in mutant KRAS lung adenocarcinoma (LUAD) is a challenge. This study analyzes the effects of trametinib on Id1 protein, a ke
Externí odkaz:
https://doaj.org/article/a7f566efdb754d68bd28062af5ab4148
Autor:
Diego de Miguel‑Perez, Murat Ak, Priyadarshini Mamindla, Alessandro Russo, Serafettin Zenkin, Nursima Ak, Vishal Peddagangireddy, Luis Lara‑Mejia, Muthukumar Gunasekaran, Andres F. Cardona, Aung Naing, Fred R. Hirsch, Oscar Arrieta, Rivka R. Colen, Christian Rolfo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-6 (2024)
Abstract Background Immune-checkpoint inhibitors (ICIs) have showed unprecedent efficacy in the treatment of patients with advanced non-small cell lung cancer (NSCLC). However, not all patients manifest clinical benefit due to the lack of reliable pr
Externí odkaz:
https://doaj.org/article/aef1eb16e7a04127b7be386a1b11b7d4
Autor:
Marzia Del Re, Giovanna Irene Luculli, Iacopo Petrini, Andrea Sbrana, Vieri Scotti, Diego de Miguel Perez, Lorenzo Livi, Stefania Crucitta, Mauro Iannopollo, Francesca Mazzoni, Martina Ruglioni, Carmelo Tibaldi, Emanuela Olmetto, Irene Stasi, Editta Baldini, Giacomo Allegrini, Lorenzo Antonuzzo, Franco Morelli, Andrea Pierini, Nicola Panzeri, Stefano Fogli, Antonio Chella, Christian Rolfo, Romano Danesi
Publikováno v:
Translational Oncology, Vol 41, Iss , Pp 101869- (2024)
Background: The present study evaluates the utility of NGS analysis of circulating free DNA (cfDNA), which incorporates small amounts of tumor DNA (ctDNA), at diagnosis or at disease progression (PD) in NSCLC patients. Methods: Comprehensive genomic
Externí odkaz:
https://doaj.org/article/262397be030b4702b3e34b61b234daba
Autor:
Diego de Miguel-Perez, Francisco Gabriel Ortega, Rosario Guerrero Tejada, Antonio Martínez-Única, Christine B. Peterson, Alessandro Russo, Muthukumar Gunasekaran, Andres F. Cardona, Victor Amezcua, Jose Antonio Lorente, Jose Expósito Hernández, Christian Rolfo, Maria Jose Serrano
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Concurrent chemoradiotherapy (cCRT) is the mainstay of treatment for patients diagnosed with locally advanced non-small cell lung cancer (NSCLC). One significant challenge in the effectiveness of this therapy is the potential development of
Externí odkaz:
https://doaj.org/article/54cef4701eaf47f1b498e777f8744fa9
Time-Dependent Effects of Clinical Interventions on SARS-CoV-2 Immunity in Patients with Lung Cancer
Autor:
Philip C. Mack, Chih-Yuan Hsu, Ananda M. Rodilla, Jorge E. Gomez, Jazz Cagan, Yuanhui Huang, Sooyun Tavolacci, Rajesh M. Valanparambil, Nicholas Rohs, Rachel Brody, Brittney Nichols, Juan Manuel Carreño, Sheena Bhalla, Christian Rolfo, David E. Gerber, Amy Moore, Jennifer C. King, Rafi Ahmed, John D. Minna, Paul A. Bunn, Adolfo García-Sastre, Florian Krammer, Fred R. Hirsch, Yu Shyr
Publikováno v:
Vaccines, Vol 12, Iss 7, p 713 (2024)
In patients with lung cancer (LC), understanding factors that impact the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti-spike antibody (SAb) titers over time is critical, but challenging, due to evolving treatments, inf
Externí odkaz:
https://doaj.org/article/c8cc0c60eaba4193bcab4968d29b9d80
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Toll-like receptors (TLRs), which serve as a bridge between innate and adaptive immunity, may be viable treatment targets. TLRs are the first line of defense against microbes and activate signaling cascades that induce immune and inflammator
Externí odkaz:
https://doaj.org/article/3c627ad5b5794403808ad9fa8da3190d
Autor:
Li Zhang, Goetz Kloecker, Christian Rolfo, Wallace Akerley, Miklos Pless, Lubos Petruzelka, Zoran Andric, Joachim Aerts, Libor Havel, Jeffrey Ward, Richard Greil, David E Gerber, Janusz Milanowski, Angelo Delmonte, Sujith Kalmadi, Rodryg Ramlau, Rupesh Kotecha, Corey Langer, Ticiana A Leal, Manuel Cobo Dols, Jaromír Roubec, Thierry Berghmans, Rajiv Panikkar, Michael Eaton, Mussawar Iqbal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d606e4f0232746d8b3133a817cfbb80c
Autor:
Alessandro Russo, Christian Rolfo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/c4418a03e59b427a8cc8ee84d124b1c9
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104605- (2023)
Externí odkaz:
https://doaj.org/article/44c7a24c938f4164ac1c3db6538d810b
Autor:
Diego de Miguel-Perez, Alessandro Russo, Oscar Arrieta, Murat Ak, Feliciano Barron, Muthukumar Gunasekaran, Priyadarshini Mamindla, Luis Lara-Mejia, Christine B. Peterson, Mehmet E. Er, Vishal Peddagangireddy, Francesco Buemi, Brandon Cooper, Paolo Manca, Rena G. Lapidus, Ru-Ching Hsia, Andres F. Cardona, Aung Naing, Sunjay Kaushal, Fred R. Hirsch, Philip C. Mack, Maria Jose Serrano, Vincenzo Adamo, Rivka R. Colen, Christian Rolfo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-14 (2022)
Abstract Background Immune-checkpoint inhibitors (ICIs) changed the therapeutic landscape of patients with lung cancer. However, only a subset of them derived clinical benefit and evidenced the need to identify reliable predictive biomarkers. Liquid
Externí odkaz:
https://doaj.org/article/4c65ef22566e4f538c868b2b0b00c400