Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Christian Rantzau"'
Autor:
Mette Brogaard Egede, Frank P. Alford, Klaus Levin, Christian Rantzau, Henning Beck-Nielsen, Jan-Erik Henriksen, Tina Trier Durck
Publikováno v:
Alford, F P, Rantzau, C, Henriksen, J-E, Egede, M B, Durck, T T, Levin, K & Beck-Nielsen, H 2014, ' Endogenous incretin hormone augmentation of acute insulin secretion in normoglycemic relatives of type 2 diabetic subjects : a 10-year retrospective pathophysiological study ', Journal of Clinical Endocrinology and Metabolism, vol. 99, no. 10, pp. E1943-E1950 . https://doi.org/10.1210/jc.2014-1644
AIMS/HYPOTHESIS: The pathophysiological role of gut incretin hormone argumentation on acute insulin release in the genesis of type 2 diabetes (TDM2) is uncertain. We examined retrospectively at 0 year and 10 years the endogenous incretin hormone acti
Autor:
Tina Trier Durck, Frank P. Alford, Jan Erik Henriksen, Glenn M. Ward, Henning Beck-Nielsen, Mette Brogaard Egede, Klaus Levin, Christian Rantzau
Publikováno v:
Egede, M B, Henriksen, J-E, Durck, T T, Levin, K, Rantzau, C, Ward, G, Beck-Nielsen, H & Alford, F P 2014, ' Glucose effectiveness in nondiabetic relatives : dysglycemia and β-cell function at 10 years ', Journal of Clinical Endocrinology and Metabolism, vol. 99, no. 4, pp. 1420-1424 . https://doi.org/10.1210/jc.2013-3273
AIMS: Reduced glucose effectiveness is a predictor of future glucose tolerance in individuals with a family history of type 2 diabetes. We examined retrospectively at 10 years in normoglycemic relatives of diabetic subjects (RELs) the pathophysiologi
Autor:
Frank P. Alford, Henning Beck-Nielsen, Tina Trier Durck, Glenn M. Ward, Mette Brogaard Egede, Jan Erik Henriksen, Klaus Levin, Christian Rantzau
Publikováno v:
Diabetes/Metabolism Research and Reviews. 29:492-498
Background This study aimed to compare the metabolic and insulin secretory responses to dexamethasone with the metabolic responses observed at 10 years in normoglycaemic relatives of type 2 diabetic and healthy control subjects. Methods Twenty relati
Autor:
Åshild Bjørnerem, Tuan V. Nguyen, John L. Hopper, Ego Seeman, Roger Zebaze, Ali Ghasem-Zadeh, Minh Bui, Xiaofang Wang, Christian Rantzau
Publikováno v:
Bone. 49:1125-1130
All postmenopausal women become estrogen deficient but not all remodel their skeleton rapidly or lose bone rapidly. As remodeling requires a surface to be initiated upon, we hypothesized that a volume of mineralized bone assembled with a larger inter
Autor:
Henning Beck-Nielsen, Frank P. Alford, Glenn M. Ward, Jan Erik Henriksen, Raymond C. Boston, Peter Thye-Rønn, Ole Hother-Nielsen, Klaus Levin, Christian Rantzau
Publikováno v:
Henriksen, J E, Alford, F, Ward, G, Thye-Rønn, P, Levin, K, Hother-Nielsen, O, Rantzau, C, Boston, R & Beck-Nielsen, H 2010, ' Glucose effectiveness and insulin sensitivity measurements derived from the non-insulin-assisted minimal model and the clamp techniques are concordant ', Diabetes-Metabolism: Research and Reviews (Print Edition), vol. 26, no. 7, pp. 569-78 . https://doi.org/10.1002/dmrr.1127
Background We investigated the concordance between glucose effectiveness (SG) and insulin sensitivity (SI), derived from the unmodified dynamic non-insulin-assisted intravenous glucose tolerance test (IVGTT) implemented by SGMM and SIMM; simulation a
Publikováno v:
Alford, F P, Henriksen, J E, Rantzau, C & Beck-Nielsen, H 2018, ' Glucose effectiveness is a critical pathogenic factor leading to glucose intolerance and type 2 diabetes : An ignored hypothesis ', Diabetes-Metabolism: Research and Reviews (Print Edition), vol. 34, no. 4, e2989 . https://doi.org/10.1002/dmrr.2989
Background: Although the ability of glucose to mediate its own in vivo metabolism is long documented, the quantitative measurement of whole body glucose-mediated glucose disposal at basal insulin levels (glucose effectiveness [GE]), followed the intr
Autor:
Sofianos Andrikopoulos, Russell Bouwman, Joseph Proietto, Barbara C Fam, Matthew J. Watt, Jenny M Favaloro, Christian Rantzau, Benjamin J. Lamont, Sherley Visinoni, Amy R. Blair
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 295:E1132-E1141
Increased endogenous glucose production (EGP) predominantly from the liver is a characteristic feature of type 2 diabetes, which positively correlates with fasting hyperglycemia. Gluconeogenesis is the biochemical pathway shown to significantly contr
Autor:
Melkam A. Kebede, Sofianos Andrikopoulos, Nicole Wong, Margaret Shaw, Jenny E. Gunton, Barbara C Fam, Anthony Zulli, Joseph Proietto, D. Ross Laybutt, Christian Rantzau, Kathryn Aston-Mourney, Jenny M Favaloro
Publikováno v:
Diabetes. 57:1887-1895
OBJECTIVE—Fructose-1,6-bisphosphatase (FBPase) is a gluconeogenic enzyme that is upregulated in islets or pancreatic β-cell lines exposed to high fat. However, whether specific β-cell upregulation of FBPase can impair insulin secretory function i
Publikováno v:
Journal of Applied Physiology. 104:363-370
The increased energy required for acute moderate exercise by skeletal muscle (SkM) is derived equally from enhanced fatty acid (FA) oxidation and glucose oxidation. Availability of FA also influences contracting SkM metabolic responses. Whole body gl
Autor:
M. Christopher, Frank P. Alford, Rodney J. Snow, Bruce E. Kemp, Zee-Ping Chen, Christian Rantzau
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 291:E1131-E1140
AMPK plays a central role in influencing fuel usage and selection. The aim of this study was to analyze the impact of low-dose AMP analog 5-aminoimidazole-4-carboxamide-1-β-d-ribosyl monophosphate (ZMP) on whole body glucose turnover and skeletal mu