Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christian R. Palmer"'
Autor:
Max E. Jacobson, Kyle W. Becker, Christian R. Palmer, Lucinda E. Pastora, R. Brock Fletcher, Kathryn A. Collins, Olga Fedorova, Craig L. Duvall, Anna M. Pyle, John. T. Wilson
Publikováno v:
ACS Central Science, Vol 6, Iss 11, Pp 2008-2022 (2020)
Externí odkaz:
https://doaj.org/article/ef66629116e647d1a850844f9ead6a49
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199399 (2018)
The FoxP2 transcription factor and its target genes have been implicated in developmental brain diseases with a prominent language component, such as developmental verbal dyspraxia and specific language impairment. How FoxP2 affects neural circuitry
Externí odkaz:
https://doaj.org/article/7c0ff7a8d1ba4cc8b8d1174560a4a56a
Autor:
Christian R. Palmer, Venkata R. Krishnamurthy, David Ulkoski, Alan Sabirsh, John T. Wilson, Max E. Jacobson, Michael J. Munson, Carcia S. Carson
Publikováno v:
ACS Applied Bio Materials. 4:1640-1654
In recent years, there has been an increasing interest in designing delivery systems to enhance the efficacy of RNA-based therapeutics. Here, we have synthesized copolymers comprised of dimethylaminoethyl methacrylate (DMAEMA) or diethylaminoethyl me
Autor:
Mohamed Wehbe, Plamen P. Christov, Carcia S. Carson, Jessalyn J. Baljon, Kyle W. Becker, Christian R. Palmer, Sebastian Joyce, Frances C. Knight, Naveenchandra Suryadevara, Amrendra Kumar, John T. Wilson, Daniel Shae
Publikováno v:
ACS Nano
Cancer vaccines targeting patient-specific neoantigens have emerged as a promising strategy for improving responses to immune checkpoint blockade. However, neoantigenic peptides are poorly immunogenic and inept at stimulating CD8(+) T cell responses,
Autor:
Mohamed Wehbe, Kameron V. Kilchrist, Plamen P. Christov, Pedro Seber, Craig L. Duvall, Lucinda E. Pastora, Dinh Chuong Nguyen, Christian R. Palmer, Kyle W. Becker, Hayden M. Pagendarm, John T. Wilson, Daniel Shae
Publikováno v:
Adv Healthc Mater
Cyclic dinucleotide (CDN) agonists of stimulator of interferon genes (STING) hold great therapeutic potential, but their activity is hindered by poor drug-like properties that restrict cytosolic bioavailability. Here, this challenge is addressed thro
Autor:
Lucinda E. Pastora, Max E. Jacobson, Kathryn A Collins, Kyle W. Becker, Christian R. Palmer, Anna Marie Pyle, Craig L. Duvall, Olga Fedorova, John T. Wilson, R. Brock Fletcher
Publikováno v:
ACS Central Science, Vol 6, Iss 11, Pp 2008-2022 (2020)
ACS Central Science
ACS Central Science
RNA ligands of retinoic acid-inducible gene I (RIG-I) hold significant promise as antiviral agents, vaccine adjuvants, and cancer immunotherapeutics, but their efficacy is hindered by inefficient intracellular delivery to the cytosol where RIG-I is l
Publikováno v:
Bioconjugate Chemistry. 29:742-747
Retinoic acid-inducible gene I (RIG-I) is a cytosolic pattern recognition receptor (PRR) that potently activates antiviral innate immunity upon recognition of 5’ triphosphorylated doublestranded RNA (pppRNA). Accordingly, RNA ligands of the RIG-I
Autor:
Kameron V. Kilchrist, Mohamed Wehbe, Hayden M. Pagendarm, Kyle W. Becker, Christian R. Palmer, John T. Wilson, Craig L. Duvall, Daniel Shae, Plamen P. Christov, Dinh Chuong Nguyen, Lucinda E. Pastora, Pedro Seber
Publikováno v:
Advanced Healthcare Materials. 10:2170004