Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Christian R. Noe"'
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2240 (2022)
Evidence-based pain therapy should rely on precisely defined and personalized criteria. This includes balancing the benefits and risks not only of single drugs but often requires complex between-drug comparisons. Non-steroidal anti-inflammatory drugs
Externí odkaz:
https://doaj.org/article/8ea19f8d64904084ae7c8b01c7e94021
Autor:
Christian R. Noe, Marion Noe-Letschnig, Patricia Handschuh, Chiara Anna Noe, Rupert Lanzenberger
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
The vascular endothelium in the brain is an essential part of the blood-brain-barrier (BBB) because of its very tight structure to secure a functional and molecular separation of the brain from the rest of the body and to protect neurons from pathoge
Externí odkaz:
https://doaj.org/article/c4c0423d308344ab8870b2e75b590bff
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 4, Pp 6399-6411 (2014)
Recombinant monoclonal antibodies (rmAbs) are medicinal products obtained by rDNA technology. Consequently, like other biopharmaceuticals, they require the extensive and rigorous characterization of the quality attributes, such as identity, structura
Externí odkaz:
https://doaj.org/article/6900a1e0836746e8a7fd6ec3429e1c45
Autor:
Bodo Lachmann, Simon Eppacher, Christian Miculka, Christian R. Noe, Peter Richter, Jerome Freissmuth
Publikováno v:
Life, Vol 3, Iss 3, Pp 486-501 (2013)
Experiments will be presented and reviewed to support the hypothesis that the intrinsic reactivity of formaldehyde may lead to the formation of a rather comprehensive set of defined biomolecules, including D-glucose, thus fostering concepts of evolut
Externí odkaz:
https://doaj.org/article/7ac96c50d1f54c04bbb36885837e2664
Autor:
Chiara Anna Noe, Marion Noe-Letschnig, Christian R. Noe, Rupert Lanzenberger, Patricia Handschuh
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience
The vascular endothelium in the brain is an essential part of the blood-brain-barrier (BBB) because of its very tight structure to secure a functional and molecular separation of the brain from the rest of the body and to protect neurons from pathoge
Publikováno v:
Nachrichten aus der Chemie. 69:108-108
Publikováno v:
European Journal of Medicinal Chemistry. 121:132-142
Ligand conjugation to oligonucleotides is an attractive strategy for enhancing the therapeutic potential of antisense and siRNA agents by inferring properties such as improved cellular uptake or better pharmacokinetic properties. Disulfide linkages e
Publikováno v:
Future Medicinal Chemistry. 7:1657-1673
Background: Despite recent advances, major hurdles still need to be cleared for widespread application of therapeutic antisense technologies. In particular, pharmacokinetic properties and efficient cellular uptake need to be improved through chemical
Autor:
Simon Eppacher, Peter Gärtner, Ernst Urban, Günter Gmeiner, Keramatollah Mehraban, Christian R. Noe
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 145:1631-1641
A new class of enantiomerically pure lactols is presented that react with rac-alkylarylcarbinols in high diastereoselectivity and can be used for the extractive racemate resolution of alkylarylcarbinols.
Autor:
Carl C. Peck, Christian R. Noe, Geoffrey T. Tucker, Malcolm Rowland, Luc Besançon, Dennis A. Smith, Mario L. Rocci, Vinod P. Shah, Daan J.A. Crommelin
Publikováno v:
Journal of Pharmaceutical Sciences. 101:4075-4099
During the last century, particularly the latter half, spectacular progress has been made in improving the health and longevity of people. The reasons are many, but the development of medicines has played a critical role. This report documents and re