Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Christian R. H. Raetz"'
Autor:
Christian Sohlenkamp, Kanaan A. Galindo-Lagunas, Ziqiang Guan, Pablo Vinuesa, Sally Robinson, Jane Thomas-Oates, Christian R. H. Raetz, Otto Geiger
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 20, Iss 11, Pp 1421-1430 (2007)
Lysyl-phosphatidylglycerol (LPG) is a well-known membrane lipid in several gram-positive bacteria but is almost unheard of in gram-negative bacteria. In Staphylococcus aureus, the gene product of mprF is responsible for LPG formation. Low pH-inducibl
Externí odkaz:
https://doaj.org/article/eb0a2125b5794192b61e30cf25ee6fb5
Publikováno v:
Journal of Molecular Biology. 430:4036-4048
During lipopolysaccharide biosynthesis in several pathogens, including Burkholderia and Yersinia, 3-deoxy- d -manno-oct-2-ulosonic acid (Kdo) 3-hydroxylase, otherwise referred to as KdoO, converts Kdo to d -glycero- d -talo-oct-2-ulosonic acid (Ko) i
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
UDP-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (LpxA) catalyzes the first step of lipid A biosynthesis, the transfer of an R-3-hydroxyacyl chain from its acyl carrier protein (ACP) to the 3-OH group of UDP-GlcNAc. Essential in the growth of Gra
Publikováno v:
Journal of molecular biology. 430(21)
During lipopolysaccharide (LPS) biosynthesis in several pathogens, including Burkholderia and Yersinia, 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) 3-hydroxylase, otherwise referred to as KdoO, converts Kdo to D-glycero-D-talo-oct-2-ulosonic acid (Ko)
Autor:
Oswald Quehenberger, Kaoru Saijo, Christopher S. Morello, H. Alex Brown, David W. Russell, Eoin Fahy, Jeffrey G. McDonald, Norihito Shibata, M. Cameron Sullards, Jesse N. Fox, Michael T. Lam, Andrea Crotti, Robert C. Murphy, Casey E. Romanoski, Nathanael J. Spann, Alfred H. Merrill, Edward A. Dennis, Shankar Subramaniam, Christian R. H. Raetz, Deborah H. Spector, Donna Reichart, Minna U. Kaikkonen, Christopher K. Glass, Aaron F. Carlin, Douglas R. Cavener, Mano Ram Maurya
Publikováno v:
The Journal of biological chemistry, vol 288, iss 50
25-Hydroxycholesterol (25OHC) is an enzymatically derived oxidation product of cholesterol that modulates lipid metabolism and immunity. 25OHC is synthesized in response to interferons and exerts broad antiviral activity by as yet poorly characterize
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:1250-1259
The lipid A component of lipopolysaccharide from the nitrogen-fixing plant endosymbiont, Rhizobium etli, is structurally very different from that found in most enteric bacteria. The lipid A from free-living R. etli is structurally heterogeneous and e
Publikováno v:
Molecular Microbiology. 89:52-64
Summary The PhoQ/PhoP two-component system activates many genes for lipopolysaccharide (LPS) modification when cells are grown at low Mg2+ concentrations. An additional target of PhoQ and PhoP is MgrR, an Hfq-dependent small RNA that negatively regul
Autor:
rd Roy Curtiss, C. Michael Reynolds, Hak Suk Chung, David A. Six, Wei Sun, Christian R. H. Raetz
Publikováno v:
Infection and Immunity. 81:1172-1185
Synthesis of Escherichia coli LpxL, which transfers a secondary laurate chain to the 2′ position of lipid A, in Yersinia pestis produced bisphosphoryl hexa-acylated lipid A at 37°C, leading to significant attenuation of virulence. Our previous obs
Publikováno v:
Biochemistry. 52:2280-2290
The sixth step in the lipid A biosynthetic pathway involves phosphorylation of the tetraacyldisaccharide-1-phosphate (DSMP) intermediate by the cytosol-facing inner membrane kinase LpxK, a member of the P-loop-containing nucleoside triphosphate (NTP)