Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christian R, Marks"'
Publikováno v:
J Neurochem
Brain endocannabinoids serve as retrograde neurotransmitters, being synthesized in post-synaptic neurons "on demand" and released to bind pre-synaptic cannabinoid receptors and suppress glutamatergic or GABAergic transmission. The most abundant brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab943454c7a2ae427c1690f55aa444e
https://doi.org/10.1111/jnc.14972
https://doi.org/10.1111/jnc.14972
Autor:
Jason R. Stephenson, Xiaohan Wang, Roger J. Colbran, Christian R. Marks, Brian C. Shonesy, Colleen M. Niswender
Publikováno v:
Molecular Pharmacology. 94:1352-1362
Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and metabotropic glutamate receptor 5 (mGlu(5)) are critical signaling molecules in synaptic plasticity and learning/memory. Here, we demonstrate that mGlu(5) is present in CaMKIIα complexes iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f5cdb087a6ab1a9f013bfa68a9c160
https://doi.org/10.1124/mol.118.113142
https://doi.org/10.1124/mol.118.113142
Autor:
Oakleigh M. Folkes, Danny G. Winder, Ken Mackie, Shana M. Augustin, Walker P. Parrish, Samuel W. Centanni, Jason R. Stephenson, Roger J. Colbran, David M. Lovinger, Hala K. Haddad, Sachin Patel, Brian C. Shonesy, Keeley L. Spiess, Rebecca J. Bluett, Rita Báldi, Christian R. Marks
Publikováno v:
Biological Psychiatry. 84:304-315
Background Endocannabinoid signaling plays an important role in regulating synaptic transmission in the striatum, a brain region implicated as a central node of dysfunction in autism spectrum disorder. Deficits in signaling mediated by the endocannab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4bdda1437b5ca7db890d38e5a9f033
https://doi.org/10.1016/j.biopsych.2017.11.036
https://doi.org/10.1016/j.biopsych.2017.11.036
Autor:
James S. Sutcliffe, Tyler L. Perfitt, Roger J. Colbran, Xiaohan Wang, Walker P. Parrish, Brian C. Shonesy, Douglas P. Mortlock, Christian R. Marks, Jason R. Stephenson, Terunaga Nakagawa
Publikováno v:
The Journal of Neuroscience. 37:2216-2233
Characterizing the functional impact of novel mutations linked to autism spectrum disorder (ASD) provides a deeper mechanistic understanding of the underlying pathophysiological mechanisms. Here we show that ade novoGlu183 to Val (E183V) mutation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a5b0e40edf654a878bdfb445ac4dc8b
https://doi.org/10.1523/jneurosci.2068-16.2017
https://doi.org/10.1523/jneurosci.2068-16.2017
Autor:
Christian R. Marks, Roger J. Colbran, Amy S. Lee, David A. Jacobson, Xiaohan Wang, Tyler L. Perfitt, Terunaga Nakagawa
Neuronal excitation can induce new mRNA transcription, a phenomenon called excitation-transcription (E-T) coupling. Among several pathways implicated in E-T coupling, activation of voltage-gated L-type Ca2+ channels (LTCCs) in the plasma membrane can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ee25424b1207728a2727b2de092521
https://europepmc.org/articles/PMC5655510/
https://europepmc.org/articles/PMC5655510/
Autor:
Karen Y. Stokes, Christian R. Marks, Igor L. Leskov, Evgeny Senchenkov, Jerry L. Brunson, Mikhail V. Khoretonenko
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 307:H1745-H1753
Cytomegalovirus (CMV) infects a majority of the population worldwide. It has been implicated in cardiovascular disease, induces microvascular dysfunction, and synergizes with hypercholesterolemia to promote leukocyte and platelet recruitment in venul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129c699e82e7651dbd22a6037b952754
https://doi.org/10.1152/ajpheart.00201.2014
https://doi.org/10.1152/ajpheart.00201.2014
Autor:
Jason R, Stephenson, Xiaohan, Wang, Tyler L, Perfitt, Walker P, Parrish, Brian C, Shonesy, Christian R, Marks, Douglas P, Mortlock, Terunaga, Nakagawa, James S, Sutcliffe, Roger J, Colbran
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(8)
Characterizing the functional impact of novel mutations linked to autism spectrum disorder (ASD) provides a deeper mechanistic understanding of the underlying pathophysiological mechanisms. Here we show that a de novo Glu183 to Val (E183V) mutation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24c93821042b8a59100b2b9748fa276c
https://pubmed.ncbi.nlm.nih.gov/28130356
https://pubmed.ncbi.nlm.nih.gov/28130356