Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Christian R, Landry"'
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 5, Pp 549-572 (2024)
Abstract Biological systems can gain complexity over time. While some of these transitions are likely driven by natural selection, the extent to which they occur without providing an adaptive benefit is unknown. At the molecular level, one example is
Externí odkaz:
https://doaj.org/article/cf3efa538f3640cd8737509487af3cf2
Autor:
Francois D Rouleau, Alexandre K Dubé, Isabelle Gagnon-Arsenault, Soham Dibyachintan, Alicia Pageau, Philippe C Després, Patrick Lagüe, Christian R Landry
Publikováno v:
PLoS Genetics, Vol 20, Iss 4, p e1011252 (2024)
Pneumocystis jirovecii is a fungal pathogen that causes pneumocystis pneumonia, a disease that mainly affects immunocompromised individuals. This fungus has historically been hard to study because of our inability to grow it in vitro. One of the main
Externí odkaz:
https://doaj.org/article/02de62579ea74a79aa374817d42790d2
Publikováno v:
eLife, Vol 12 (2024)
Transposable elements (TEs) are major contributors to structural genomic variation by creating interspersed duplications of themselves. In return, structural variants (SVs) can affect the genomic distribution of TE copies and shape their load. One lo
Externí odkaz:
https://doaj.org/article/625e9cf03a3742e0a2330a604f555fb5
Autor:
Laura Kienzle, Stefano Bettinazzi, Thierry Choquette, Marie Brunet, Hajar Hosseini Khorami, Jean-François Jacques, Mathilde Moreau, Xavier Roucou, Christian R. Landry, Annie Angers, Sophie Breton
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Mitochondria have a central role in cellular functions, aging, and in certain diseases. They possess their own genome, a vestige of their bacterial ancestor. Over the course of evolution, most of the genes of the ancestor have bee
Externí odkaz:
https://doaj.org/article/043535a21609424d9989f47132b8c531
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1011002 (2023)
Pathogenic fungi are a cause of growing concern. Developing an efficient and safe antifungal is challenging because of the similar biological properties of fungal and host cells. Consequently, there is an urgent need to better understand the mechanis
Externí odkaz:
https://doaj.org/article/dc7872efc2ab40ebba7edb864aa2e480
Autor:
David Peris, Emily J. Ubbelohde, Meihua Christina Kuang, Jacek Kominek, Quinn K. Langdon, Marie Adams, Justin A. Koshalek, Amanda Beth Hulfachor, Dana A. Opulente, David J. Hall, Katie Hyma, Justin C. Fay, Jean-Baptiste Leducq, Guillaume Charron, Christian R. Landry, Diego Libkind, Carla Gonçalves, Paula Gonçalves, José Paulo Sampaio, Qi-Ming Wang, Feng-Yan Bai, Russel L. Wrobel, Chris Todd Hittinger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Here, the authors describe the geographies, hosts, substrates, and phylogenetic relationships for 1,794 Saccharomyces strains. They provide insight into the genetic and phenotypic diversity in the genus, not seen through prior work focused on the mod
Externí odkaz:
https://doaj.org/article/87582f43464b458fbd1cfe074f6265cc
Publikováno v:
PLoS Genetics, Vol 19, Iss 5, p e1010756 (2023)
How changes in the different steps of protein synthesis-transcription, translation and degradation-contribute to differences of protein abundance among genes is not fully understood. There is however accumulating evidence that transcriptional diverge
Externí odkaz:
https://doaj.org/article/3cdf9d10f1fb4589ac8500f76bf96f88
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002042 (2023)
The biophysical properties of the cytoplasm are major determinants of key cellular processes and adaptation. Many yeasts produce dormant spores that can withstand extreme conditions. We show that spores of Saccharomyces cerevisiae exhibit extraordina
Externí odkaz:
https://doaj.org/article/6000cc4003f04ff3a0f79b2ce0b9b1e0
Autor:
Chloé Suzanne Berger, Jérôme Laroche, Halim Maaroufi, Hélène Martin, Kyung-Mee Moon, Christian R. Landry, Leonard J. Foster, Nadia Aubin-Horth
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-20 (2021)
Abstract Background Manipulative parasites are thought to liberate molecules in their external environment, acting as manipulation factors with biological functions implicated in their host’s physiological and behavioural alterations. These manipul
Externí odkaz:
https://doaj.org/article/03cd9bd5ffaf4e83b57091710caf05dc
Autor:
Godai Suzuki, Yutaka Saito, Motoaki Seki, Daniel Evans-Yamamoto, Mikiko Negishi, Kentaro Kakoi, Hiroki Kawai, Christian R. Landry, Nozomu Yachie, Toutai Mitsuyama
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Morphological profiling is a combination of established optical microscopes and cutting-edge machine vision technologies, which stacks up successful applications in high-throughput phenotyping. One major question is how much information can
Externí odkaz:
https://doaj.org/article/66aefc2368b74bae83b5e15802ae8fec