Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christian Queckenberg"'
Autor:
Xia Li, Juliane Iltgen-Breburda, Christian Queckenberg, Malaz Gazzaz, Matthias Schwab, Martin Jübner, Max Taubert, Elke Schaeffeler, Marc S. Stoffel, Daria Kraus, Chih-hsuan Hsin, Fritz Sörgel, Uwe Fuhr, Martina Kinzig, Christina Trueck
Publikováno v:
Clinical Pharmacology & Therapeutics
We quantified the effect of acute ethanol exposure (initial blood concentrations 0.7 g/L) on major drug metabolizing enzymes and p-glycoprotein. Sixteen healthy Caucasians participated in a randomized crossover study with repeated administration of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ddc93f0fb5f6e30c4717b79a754ce2
https://pubmed.ncbi.nlm.nih.gov/30515759
https://pubmed.ncbi.nlm.nih.gov/30515759
Autor:
Christian Queckenberg, Daria Kraus, Ahmed Abbas Suleiman, Paola Di Gion, Uta Kerkweg, Dennis Rokitta, Dorota Tomalik-Scharte, Uwe Fuhr, Sebastian Frechen
Publikováno v:
The Journal of Clinical Pharmacology. 54:1162-1169
Diurnal changes in the activity of drug metabolizing enzymes may contribute to the variability in drug disposition and drug effects. The aim of this study was to quantify the circadian rhythmicity exhibited by hepatic CYP3A. A 10 μg/kg intravenous b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::449b10c7724c9b9f74b90a4567d057da
https://doi.org/10.1002/jcph.318
https://doi.org/10.1002/jcph.318
Autor:
Bertil Wachall, Kathleen Gerbeth, Paola Di Gion, Dorota Tomalik-Scharte, Christian Queckenberg, Mona Tawab, Valerie Erlinghagen, Uwe Fuhr
Publikováno v:
Clinical Therapeutics. 33:1831-1841
Dexamethasone is a glucocorticoid used widely worldwide for immunosuppressive treatment, allergies, bronchiolitis, and croup, among others. For children, liquid formulations are especially suitable because, compared with other dosage forms, both exac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaade31f3022f99aa5be1e530812d680
https://doi.org/10.1016/j.clinthera.2011.10.006
https://doi.org/10.1016/j.clinthera.2011.10.006
Autor:
S. H. G. Van Os, V. Erlinghagen, M. Wargenau, V. Kubeš, V. Novotný, B. C. M. Baken, Uwe Fuhr, Christian Queckenberg, R. Peroutka
Publikováno v:
Cancer Chemotherapy and Pharmacology, 76, 5, pp. 1081-91
Cancer Chemotherapy and Pharmacology, 76, 1081-91
Cancer Chemotherapy and Pharmacology, 76, 1081-91
Item does not contain fulltext PURPOSE: To describe concentration versus time profiles of capecitabine and its metabolites 5'-DFUR, 5'-DFCR and 5-FU, depending on tablet formulation and on frequent and/or relevant genetic polymorphisms of cytidine de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28584128d88e1f2f5cac06e8ca599bd
https://pubmed.ncbi.nlm.nih.gov/26242222
https://pubmed.ncbi.nlm.nih.gov/26242222
Autor:
Dorota, Tomalik-Scharte, Ahmed Abbas, Suleiman, Sebastian, Frechen, Daria, Kraus, Uta, Kerkweg, Dennis, Rokitta, Paola, Di Gion, Christian, Queckenberg, Uwe, Fuhr
Publikováno v:
Journal of clinical pharmacology. 54(10)
Diurnal changes in the activity of drug metabolizing enzymes may contribute to the variability in drug disposition and drug effects. The aim of this study was to quantify the circadian rhythmicity exhibited by hepatic CYP3A. A 10 μg/kg intravenous b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4c9e3293679193457f8c0c7d227ad0e
https://pubmed.ncbi.nlm.nih.gov/24782075
https://pubmed.ncbi.nlm.nih.gov/24782075
Autor:
Christian Queckenberg, Oxana Doroshyenko, Bertil Wachall, Dorota Tomalik-Scharte, Jürgen Meins, Uwe Fuhr, Bärbel Bastian, Mona Abdel-Tawab
Publikováno v:
Web of Science
We evaluated the pharmacokinetics and safety of the antimicrobial agent triclosan after dermal application of a 2% triclosan-containing cream to six volunteers. Percutaneous absorption calculated from urinary excretion was 5.9% ± 2.1% of the dose (m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c0ae94655e855cd87100b75a6a863a
https://doi.org/10.1128/aac.00615-09
https://doi.org/10.1128/aac.00615-09
Autor:
Christian Queckenberg, Uwe Fuhr
Publikováno v:
European journal of clinical pharmacology. 65(2)
Body position may influence physiological characteristics, such as perfusion, gastrointestinal function and plasma volume. These characteristics may interact with key factors determining the pharmacokinetics of drugs (dissolution, absorption, distrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728e88f72e332e006261f688f2070849
https://pubmed.ncbi.nlm.nih.gov/18936930
https://pubmed.ncbi.nlm.nih.gov/18936930
Publikováno v:
Mycoses. 49
Posaconazole is a new antifungal drug used in prophylaxis and therapy of fungal infections in patients with immunodeficiency. In the clinical development, posaconazole exhibits variable oral bioavailability. Hence drug monitoring is recommended. For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd090e24ad41010374f512274e6b9f3
https://pubmed.ncbi.nlm.nih.gov/16961577
https://pubmed.ncbi.nlm.nih.gov/16961577