Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Christian Poulsen"'
Autor:
Angelo Rosace, Anja Bennett, Marc Oeller, Mie M. Mortensen, Laila Sakhnini, Nikolai Lorenzen, Christian Poulsen, Pietro Sormanni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Antibodies find key applications in research, diagnostics, and therapeutics, but their development can be impeded by poor stability or solubility. Here the authors developed a computational strategy that enables antibody optimisation, without affecti
Externí odkaz:
https://doaj.org/article/1130c0e57b5e4de4ab65ffe227965175
Autor:
Arnon Kater, Julie Dubois, Christian Brieghel, Sabina Kersting, Lisbeth Enggaard, Gerrit Veldhuis, Rogier Mous, Clemens Mellink, Johan Dobber, Christian Poulsen, Caspar Da Cunha-Bang, Hendrik Fredriksen, Ann Janssens, Ida Schjodt, Ellen Dompeling, Juha Ranti, Mattias Mattsson, Mar Bellido, Hoa Tran, Kazem Nasserinejad, Mark-David Levin, Carsten Niemann
Publikováno v:
HemaSphere, Vol 7, p e10648ed (2023)
Externí odkaz:
https://doaj.org/article/37b50e3544da4e5e91dc8c9be88c63dc
Autor:
Christian Poulsen, Yusuf Akhter, Amy Hye‐Won Jeon, Gerold Schmitt‐Ulms, Helmut E Meyer, Anja Stefanski, Kai Stühler, Matthias Wilmanns, Young‐Hwa Song
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-9 (2010)
Abstract Mycobacteria use a unique system for covalently modifying proteins based on the conjugation of a small protein, referred to as prokaryotic ubiquitin‐like protein (PUP). In this study, we report a proteome‐wide analysis of endogenous pupy
Externí odkaz:
https://doaj.org/article/1e3255fd776f4025bd206adab5773334
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89313 (2014)
Members of the WXG100 protein superfamily form homo- or heterodimeric complexes. The most studied proteins among them are the secreted T-cell antigens CFP-10 (10 kDa culture filtrate protein, EsxB) and ESAT-6 (6 kDa early secreted antigen target, Esx
Externí odkaz:
https://doaj.org/article/a67e3c1a6c84454ba0031a84ba97632b
Autor:
Simon Bressendorff, Swathi Kausika, Ida Marie Zobbe Sjøgaard, Emilie Duus Oksbjerg, Alec Michels, Christian Poulsen, Peter Brodersen
The effector complex of RNA interference (RNAi) contains at its core an ARGONAUTE (AGO) protein bound to a small guide RNA. AGO proteins adopt a two-lobed structure in which the N-terminal (N) and Piwi-Argonaute-Zwille (PAZ) domains make up one lobe,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a9a33bf26bb8e3bd29cd5dde927444d
https://doi.org/10.1101/2023.01.18.524620
https://doi.org/10.1101/2023.01.18.524620
Autor:
Kirsten Raun, Eva Johansson, Morten Schlein, Ulrich Sensfuss, Christian Poulsen, Simone Fulle, Kirsten Dahl, Lauge Schäffer, Ann Maria Kruse Hansen, Trine R. Clausen, Jakob Lerche Hansen, Charlotta Dornonville de la Cour, Rikke Bjerring Skyggebjerg, Thomas Kruse, Claus Bekker Jeppesen
Publikováno v:
Journal of Medicinal Chemistry. 64:11183-11194
A hallmark of the pancreatic hormone amylin is its high propensity toward the formation of amyloid fibrils, which makes it a challenging drug design effort. The amylin analogue pramlintide is commercially available for diabetes treatment as an adjunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eaa793c2245d270ddc8b3148f54058f
https://doi.org/10.1021/acs.jmedchem.1c00565
https://doi.org/10.1021/acs.jmedchem.1c00565
Autor:
Johan F. Paulsson, Jens Kaalby Thomsen, Annika Lindgren Sjölander, Christian Poulsen, Birgitte Schjellerup Wulff, Per-Olof Wahlund, Kilian Conde-Frieboes, Søren Østergaard, Marie Østergaard Pedersen
Publikováno v:
Pharmaceutical Research. 38:1369-1385
The anorectic effect of PYY3–36 makes it a potential pharmacological weight loss treatment. Modifications of the endogenous peptide to obtain commercially attractive pharmacological and biophysical stability properties are examined. Half-life exten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f411fe986b05fc92f7569a83399866d
https://doi.org/10.1007/s11095-021-03077-x
https://doi.org/10.1007/s11095-021-03077-x
Autor:
Mette Mønsted, Christian Poulsen
Publikováno v:
Journal of Wine Research. 31:194-217
The article investigates how wineries have used different markers as an effort to differentiate themselves from other producers and support their self-identity. The most dominant markers perceived by the respondents are tied to different forms of reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6408d911c59f65321c24062e68bfaf3
https://doi.org/10.1080/09571264.2020.1816533
https://doi.org/10.1080/09571264.2020.1816533
Autor:
Tsegaye Tadesse, Mark Svoboda, Calvin Christian Poulsen, Yared A. Bayissa, Schalk Jan van Andel, John Swigart, Brian D. Wardlow
Publikováno v:
GIScience & Remote Sensing. 56:718-748
Developing a robust drought monitoring tool is vital to mitigate the adverse impacts of drought. A drought monitoring system that integrates multiple agrometeorological variables into a single drou...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3b10f788acdf09ea83af8ac4b537fdf
https://doi.org/10.1080/15481603.2018.1552508
https://doi.org/10.1080/15481603.2018.1552508
Autor:
Christian, Poulsen, Marie Østergaard, Pedersen, Per-Olof, Wahlund, Annika, Sjölander, Jens Kaalby, Thomsen, Kilian W, Conde-Frieboes, Johan F, Paulsson, Birgitte S, Wulff, Søren, Østergaard
Publikováno v:
Pharmaceutical research. 38(8)
The anorectic effect of PYYHalf-life extended PYYDeamidation of asparagine in position 18 and 29 was observed upon incubation at 37°C. Asparagine in position 18 - but not position 29 - could be substituted to glutamine without detrimental effects on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44eba2d1563d226835592aabd480e098
https://pubmed.ncbi.nlm.nih.gov/34272643
https://pubmed.ncbi.nlm.nih.gov/34272643