Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Christian Pichoud"'
Autor:
Fabien Zoulim, Dong-Hua Zhang, Paul Dény, Zhong-Hua Lu, Vannary Mom, Yan Zhang, Yue Han, Demin Yu, Qi-Ming Gong, Xiang-Wei Liao, Xinxin Zhang, Christian Pichoud, Xin-Hua Li
Publikováno v:
Journal of Hepatology. 60:515-522
Background & Aims HBV immune escape represents a challenge to prevention, diagnosis, and treatment of hepatitis B. Here, we analyzed the molecular and clinical characteristics of HBV immune escape mutants in a Chinese cohort of chronically infected p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca08ee3a7ab9dcd2f21e9cce142d624b
https://doi.org/10.1016/j.jhep.2013.11.004
https://doi.org/10.1016/j.jhep.2013.11.004
Autor:
Christian Pichoud, Paul Dény, Kathryn M. Kitrinos, Fabien Lavocat, Katyna Borroto-Esoda, Nasser Al Hawajri, Fabien Zoulim
Publikováno v:
Journal of Hepatology. 59:684-695
Adefovir (ADV) resistance mutations induce low-level cross-resistance to tenofovir in vitro. Our aim was to compare viral kinetics, nucleos(t)ide analog resistance mutations, and quasispecies (QS) evolution during therapy with tenofovir disoproxil fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7c6cc58244876cc457cfaf9f4c71d8
https://doi.org/10.1016/j.jhep.2013.05.038
https://doi.org/10.1016/j.jhep.2013.05.038
Autor:
Christian Pichoud, Fabien Zoulim, Vincent Thibault, Alain Bitbol, Sven Thamm, Carolyn Mullen, Jane B. Smith, James Rhoads
Publikováno v:
Journal of Clinical Microbiology. 45:3948-3953
Sensitive and accurate quantification of hepatitis B virus (HBV) DNA is necessary for monitoring patients with chronic hepatitis receiving antiviral therapy in order to determine treatment response and to adapt therapy in case of inadequate virologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe9c51408449128abba64e99bf6d15a
https://doi.org/10.1128/jcm.01180-07
https://doi.org/10.1128/jcm.01180-07
Autor:
Fabien Zoulim, A. Ollivet, Luc Barraud, Jean-Pierre Villeneuve, Christian Trepo, Christian Pichoud, Stéphanie Villet
Publikováno v:
Journal of Hepatology. 46:531-538
BACKGROUND/AIMS: Complex mutants may be selected under sequential anti-VHB pressures. We analyzed the genotypic and phenotypic evolution of the viral quasi-species of a patient who developed resistance to entecavir following lamivudine breakthrough.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25169be35968b451a9f6a0d8b342896
https://doi.org/10.1016/j.jhep.2006.11.016
https://doi.org/10.1016/j.jhep.2006.11.016
Autor:
David Durantel, Sandra Carrouée-Durantel, A.C. Jacquard, Fabien Zoulim, C. Trepo, Christian Pichoud, Marie-Noëlle Brunelle
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:955-961
The fluorinated guanosine analog 2′,3′-dideoxy-3′-fluoroguanosine (FLG) was shown to inhibit wild-type (wt) hepatitis B virus (HBV) replication in a human hepatoma cell line permanently expressing HBV. Experiments performed in the duck model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6334241333c6f7335e9443cfa403f67d
https://doi.org/10.1128/aac.50.3.955-961.2006
https://doi.org/10.1128/aac.50.3.955-961.2006
Autor:
Fabien Zoulim, David Durantel, Sandra Carrouée-Durantel, Christian Pichoud, Marie-Noëlle Brunelle, Stéphanie Villet, Edwige Gros, Christian Trepo
Publikováno v:
Journal of Clinical Virology. 34:S34-S43
The treatment of HBV infected patients with analogues of nucleos(t)ides, including lamivudine and adefovir dipivoxil, has significantly increased the rate of anti-HBe seroconversion and therefore reduced the impact of chronic hepatitis B (CHB) on liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d57992168585fb10a24b053bf0a5fe7
https://doi.org/10.1016/s1386-6532(05)80008-3
https://doi.org/10.1016/s1386-6532(05)80008-3
Autor:
S. Ren, Sylviane Guerret, Fabien Zoulim, S. Peyrol, Laurence Rimsky, Michael Nassal, Ursula Schultz, Christian Pichoud, Bettina Werle, M. Chevallier, C. Trepo, A.C. Jacquard, Catherine Jamard
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2683-2692
Our aim was to evaluate the antiviral effect of a combination of two nucleoside reverse transcriptase inhibitors, emtricitabine (FTC) and clevudine (L-FMAU), with the addition of an adenovirus-driven delivery of recombinant gamma interferon (IFN-γ)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8440c549622e293e5b65647ff90039
https://doi.org/10.1128/aac.48.7.2683-2692.2004
https://doi.org/10.1128/aac.48.7.2683-2692.2004
Autor:
Fabien Zoulim, S. Germon, Yung-Chi Cheng, Christian Pichoud, Béatrice Seignères, Pascale Berthillon, F. Le Guerhier, C. Trepo
Publikováno v:
Journal of Gastroenterology and Hepatology. 17:S460-S463
Backgroud: Our aim was to evaluate the anti-HBV activity of a novel L-nucleoside analog, 2',3'-dideoxy-2',3'-didehydro-β-L-5-fluorocytidine (β-L-Fd4C), in study models of HBV infection. Method: Its mechanism of action was evaluated on the in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41acee955590fee653b4237115ea6293
https://doi.org/10.1046/j.1440-1746.17.s4.10.x
https://doi.org/10.1046/j.1440-1746.17.s4.10.x
Autor:
Cécile Grandjacques, Mireille Maisonnas, Fabien Zoulim, Michèle Chevallier, Lieven Stuyver, Christian Pichoud, Christian Trepo, Philippe Chevallier, Pierre Pradat
Publikováno v:
Journal of Hepatology. 33:430-439
We aimed to clarify the clinical relevance of hepatitis B virus pre-core mutant detection in patients with chronic hepatitis B using a newly developed assay.Viral genotypes and pre-core mutations were studied in relation to viral persistence and live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034b9d4316c8a7ca059bc03f09592192
https://doi.org/10.1016/s0168-8278(00)80279-2
https://doi.org/10.1016/s0168-8278(00)80279-2
Autor:
Christian Pichoud, Christian Trepo, Fabien Zoulim, Sinafa Si Ahmed, Olivier Hantz, Béatrice Seignères
Publikováno v:
The Journal of Infectious Diseases. 181:1221-1233
Prolonged administration of nucleoside analogues for chronic hepatitis B may result in the emergence of hepatitis B viral polymerase mutants. To gain insight into the mechanism involved in the virus's resistance to famciclovir, the amino acid sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766f61a1dac5e9deb70e717384cbf671
https://doi.org/10.1086/315368
https://doi.org/10.1086/315368