Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christian Permann"'
Publikováno v:
Molecules, Vol 26, Iss 23, p 7201 (2021)
Chemical features of small molecules can be abstracted to 3D pharmacophore models, which are easy to generate, interpret, and adapt by medicinal chemists. Three-dimensional pharmacophores can be used to efficiently match and align molecules according
Externí odkaz:
https://doaj.org/article/6d8c1b4139f74df999f102d7cf2a6a95
Autor:
Stefan M. Kohlbacher, Gökhan Ibis, Christian Permann, Sharon Bryant, Thierry Langer, Thomas Seidel
Publikováno v:
Molecular Informatics. 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207e21a5c674fc917ab1dc1487c11c7a
https://doi.org/10.1002/minf.202200245
https://doi.org/10.1002/minf.202200245
The majority of compounds in the drug-like chemical space show flexibility regarding their three-dimensional structure which, in solution, results in an equilibrium of multiple interconvertible conformational states. Knowledge of the putative bound-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf0c533ff445cbee1f2cdfa03162a11
https://doi.org/10.21203/rs.3.rs-1597257/v1
https://doi.org/10.21203/rs.3.rs-1597257/v1
