Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christian Pennanen"'
Autor:
Juan Carlos Roa, Beverly A. Rothermel, Valentina Parra, Alejandro H. Corvalan, Camila López-Crisosto, Pablo E. Morales, Iva Polakovicova, Pablo Rivera-Mejías, César Vásquez-Trincado, María Paz Ocaranza, Hung Ho-Xuan, Vinicius Maracaja-Coutinho, Victor Aliaga-Tobar, Sergio Lavandero, Cristian Sotomayor-Flores, Lorena García, Mario Chiong, Gunter Meister, Christian Pennanen
Publikováno v:
Cell Death Differ
Angiotensin-(1-9) is a peptide from the noncanonical renin-angiotensin system with anti-hypertrophic effects in cardiomyocytes via an unknown mechanism. In the present study we aimed to elucidate it, basing us initially on previous work from our grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa29cedee69a85034cb2e92634bf4b5
https://europepmc.org/articles/PMC7429871/
https://europepmc.org/articles/PMC7429871/
Autor:
Valentina Parra, Sergio Lavandero, Ivonne Garcia-Carvajal, Christian Pennanen, Beverly A. Rothermel, César Vásquez-Trincado, Joseph A. Hill
Publikováno v:
The Journal of Physiology. 594:509-525
Cardiac hypertrophy is often initiated as an adaptive response to haemodynamic stress or myocardial injury, and allows the heart to meet an increased demand for oxygen. Although initially beneficial, hypertrophy can ultimately contribute to the progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85e0bdbce26fbf67c37a5d75bed9359a
https://doi.org/10.1113/jp271301
https://doi.org/10.1113/jp271301
Autor:
Francisco Westermeier, Christian Pennanen, Alejandra P. Oyarzún, Gina Sánchez, Rodrigo Troncoso, Valentina Parra, Sergio Lavandero, Zully Pedrozo, Cristian Sotomayor-Flores, Camila López-Crisosto
Publikováno v:
Biochemical Pharmacology. 98:92-101
Aim FK866 is an inhibitor of the NAD + synthesis rate-limiting enzyme nicotinamide phosphoribosyltransferase (NAMPT). Using FK866 to target NAD + synthesis has been proposed as a treatment for inflammatory diseases and cancer. However, use of FK866 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e93acac2b0d75a5e391e54b88e638d
https://doi.org/10.1016/j.bcp.2015.08.097
https://doi.org/10.1016/j.bcp.2015.08.097
Autor:
Sergio Lavandero, Mario Chiong, Camila López-Crisosto, Christian Pennanen, Pablo E. Morales, César Vásquez-Trincado, Andrew F. G. Quest, Roberto Bravo-Sagua
Publikováno v:
Nature reviews. Cardiology. 14(6)
Repetitive, calcium-mediated contractile activity renders cardiomyocytes critically dependent on a sustained energy supply and adequate calcium buffering, both of which are provided by mitochondria. Moreover, in vascular smooth muscle cells, mitochon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34f2b6be69805864953e8167dd60737
https://pubmed.ncbi.nlm.nih.gov/28275246
https://pubmed.ncbi.nlm.nih.gov/28275246
Autor:
Jovan Kuzmicic, Andrea del Campo, Fabián Jaña, David A. Bernlohr, Camila López-Crisosto, Mario Chiong, Amira Klip, Christian Pennanen, Sergio Lavandero, Joseph A. Hill, Eduard Noguera, Yi Zhu, Valentina Parra, Rodrigo Troncoso, Myriam Iglewski, Antonio Zorzano, Hugo Verdejo, Beverly A. Rothermel, Deborah Jones, Evan Dale Abel, Jorge Ferreira
Publikováno v:
Diabetes
DIABETES
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
DIABETES
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Insulin regulates heart metabolism through the regulation of insulin-stimulated glucose uptake. Studies have indicated that insulin can also regulate mitochondrial function. Relevant to this idea, mitochondrial function is impaired in diabetic indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88bd2ac21efff4190c4b70727b414744
https://doi.org/10.2337/db13-0340
https://doi.org/10.2337/db13-0340
Autor:
Pablo Castro, Andrea del Campo, Hugo Verdejo, Sergio Lavandero, Camila López-Crisosto, Mario Chiong, Roberto Bravo-Sagua, Jonathan Hechenleitner, Jovan Kuzmicic, Pablo E. Morales, Valentina Parra, Ramiro J. Zepeda, Christian Pennanen
Publikováno v:
Revista Española de Cardiología (English Edition). 64:916-923
A B S T R A C T Mitochondria are dynamic organelles able to vary their morphology between elongated interconnected mitochondrial networks and fragmented disconnected arrays, through events of mitochondrial fusion and fission, respectively. These even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31f72bba12498ccc19ffdc7fbbc9eff6
https://doi.org/10.1016/j.rec.2011.05.022
https://doi.org/10.1016/j.rec.2011.05.022
Autor:
Hugo Verdejo, Christian Pennanen, Jonathan Hechenleitner, Mario Chiong, Pablo Castro, Andrea del Campo, Roberto Bravo-Sagua, Camila López-Crisosto, Jovan Kuzmicic, Sergio Lavandero, Pablo E. Morales, Ramiro J. Zepeda, Valentina Parra
Publikováno v:
Revista Española de Cardiología. 64:916-923
Resumen Las mitocondrias son organelos dinamicos, capaces de intercambiar su morfologia entre redes elongadas e interconectadas y arreglos fragmentados y desconectados mediante los procesos de fusion y fision mitocondrial, respectivamente. Estos even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04804ea39ed0ea257b5bf66920fd1f22
https://doi.org/10.1016/j.recesp.2011.05.018
https://doi.org/10.1016/j.recesp.2011.05.018
Autor:
Beverly A. Rothermel, Joseph A. Hill, Hugo Verdejo, Sergio Lavandero, Valentina Parra, Jovan Kuzmicic, Andrea del Campo, Myriam Iglewski, Christian Pennanen
Publikováno v:
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Mitochondria are highly dynamic organelles, capable of undergoing constant fission and fusion events, forming networks. These dynamic events allow the transmission of chemical and physical messengers and the exchange of metabolites within the cell. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3d000537a0060226301bad18c4bea3
https://doi.org/10.1007/s10863-011-9332-0
https://doi.org/10.1007/s10863-011-9332-0
Autor:
María Pilar Sánchez, Marcelo Llancaqueo, Christian Pennanen, Juan Carlos Prieto, Sergio Lavandero, Mario Chiong, Viviana Noriega
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 104:211-215
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors have been used clinically for lowering total and low-density lipoprotein cholesterol. Interindividual pharmacological differences observed with this treatment have been attributed to genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d766f852552849aa322ff01eb69eeb
https://doi.org/10.1111/j.1742-7843.2008.00341.x
https://doi.org/10.1111/j.1742-7843.2008.00341.x
Autor:
Natalia Torrealba, Alejandra San Martin, W. Robert Taylor, Christian Pennanen, Damián Gatica, Enrique Jaimovich, Mario Navarro-Marquez, Rodrigo Troncoso, Valentina Parra, Felipe Paredes, Mario Chiong, Christa Caesar, Sergio Lavandero, Clara Quiroga, Roberto Bravo-Sagua, Jordi Molgó
Publikováno v:
Free Radic Biol Med
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Europe PubMed Central
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Europe PubMed Central
Homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 1 (HERPUD1), an ER resident protein, is upregulated in response to ER stress and Ca(2+) homeostasis deregulation. HERPUD1 exerts cytoprotective effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec040bc68c5827b3572a60199bf4b07
https://europepmc.org/articles/PMC4710961/
https://europepmc.org/articles/PMC4710961/