Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Christian Paul Konken"'
Autor:
Andreas Faust, Michael Schäfers, Lisa Honold, Christian Paul Konken, Katrin Schwegmann, Günter Haufe, Sven Hermann, Melanie Austrup, Constantin G. Daniliuc, Klaus Kopka, Bastian Zinnhardt
Publikováno v:
Molecular Imaging and Biology. 24:434-443
Introduction Dysregulated activity of matrix metalloproteinases (MMPs) drives a variety of pathophysiological conditions. Non-invasive imaging of MMP activity in vivo promises diagnostic and prognostic value. However, current targeting strategies by
Autor:
Christian Paul Konken, Bernd Beutel, Benjamin Schinor, Jian Song, Hanna Gerwien, Eva Korpos, Miriam Burmeister, Burkhard Riemann, Michael Schäfers, Lydia Sorokin, Günter Haufe
Publikováno v:
Bioorganic & Medicinal Chemistry. :117350
Autor:
Marius Rieke, Zoltán Pethő, Sarah Maskri, Cristian A. Strassert, Christian Paul Konken, Oliver Koch, Iván Maisuls, Kathrin Brömmel, Bernhard Wünsch, Albrecht Schwab
Publikováno v:
Angewandte Chemie (International Ed. in English)
Small‐molecule probes for the in vitro imaging of KCa3.1 channel‐expressing cells were developed. Senicapoc, showing high affinity and selectivity for the KCa3.1 channels, was chosen as the targeting component. BODIPY dyes 15–20 were synthesize
Autor:
Dominic Alexej, Depke, Christian Paul, Konken, Lukas, Rösner, Sven, Hermann, Michael, Schäfers, Andrea, Rentmeister
Publikováno v:
Chemical communications (Cambridge, England). 57(77)
Bioorthogonal covalent labeling with self-labeling enzymes like SNAP-tag bears a high potential for specific targeting of cells for imaging
Autor:
Lisa, Honold, Melanie, Austrup, Andreas, Faust, Christian Paul, Konken, Katrin, Schwegmann, Bastian, Zinnhardt, Constantin Gabriel, Daniliuc, Günter, Haufe, Michael, Schäfers, Klaus, Kopka, Sven, Hermann
Publikováno v:
Molecular imaging and biology. 24(3)
Dysregulated activity of matrix metalloproteinases (MMPs) drives a variety of pathophysiological conditions. Non-invasive imaging of MMP activity in vivo promises diagnostic and prognostic value. However, current targeting strategies by small molecul
Autor:
Kathrin, Brömmel, Christian Paul, Konken, Frederik, Börgel, Henry, Obeng-Darko, Sonja, Schelhaas, Etmar, Bulk, Thomas, Budde, Albrecht, Schwab, Michael, Schäfers, Bernhard, Wünsch
Publikováno v:
RSC advances. 11(48)
Expression of the Ca
Autor:
Lukas Rösner, Christian Paul Konken, Dominic Alexej Depke, Andrea Rentmeister, Michael Schäfers
Publikováno v:
Current Opinion in Chemical Biology. 68:102144
Inflammation is a common, fast, and innate response of the immune system to sterile or infectious tissue damage or autoimmune triggers. It aims at minimizing tissue destruction and maintaining organ function, hence is vital to life. Therefore, the im
Autor:
Christian Paul Konken, Verena Hugenberg, Kathrin Brömmel, Stefan Wagner, Günter Haufe, Bernhard Wünsch, Michael Schäfers
Publikováno v:
Dyes and Pigments. 158:88-96
The unique properties and the usually observed high stability of fluorescent dyes based on BODIPYs ( bo ron dipyrromethin es) predestinate them for application in medicinal chemistry. Depending on the design of the environment of the boron core, a se
Autor:
Hanna Gerwien, Christian Paul Konken, Reshma Vidyadharan, Bernd Beutel, Lixia Li, Eva Korpos, Jian Song, Miriam Burmeister, Günter Haufe, Benjamin Schinor, Lydia Sorokin
Publikováno v:
Bioconjugate Chemistry. 29:3715-3725
Matrix metalloproteinases (MMPs) are emerging as pivotal fine-tuners of cell function in tissue homeostasis and in various pathologies, in particular inflammation. In vivo monitoring of the activity of specific MMPs, therefore, provides high potentia
Autor:
Alexander Axer, Christian Paul Konken, Silke Niemann, Sven Hermann, Andreas Faust, Michael Schäfers, Felicitas Landau, Sonja Schelhaas, Ryan Gilmour
Publikováno v:
Nuclear Medicine and Biology. :S8