Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Christian P Petersen"'
Autor:
Eleanor G Clark, Christian P Petersen
Publikováno v:
PLoS Genetics, Vol 19, Iss 9, p e1010608 (2023)
Adult regeneration restores patterning of orthogonal body axes after damage in a post-embryonic context. Planarians regenerate using distinct body-wide signals primarily regulating each axis dimension: anteroposterior Wnts, dorsoventral BMP, and medi
Externí odkaz:
https://doaj.org/article/cd0a87db02c646c4bcd9eb71e987657e
Publikováno v:
eLife, Vol 9 (2020)
Negative regulators of adult neurogenesis are of particular interest as targets to enhance neuronal repair, but few have yet been identified. Planarians can regenerate their entire CNS using pluripotent adult stem cells, and this process is robustly
Externí odkaz:
https://doaj.org/article/5da8d6079fcd4ff696fc55462ce4a369
Publikováno v:
PLoS Genetics, Vol 15, Iss 10, p e1008401 (2019)
Wnt signaling regulates primary body axis formation across the Metazoa, with high Wnt signaling specifying posterior identity. Whether a common Wnt-driven transcriptional program accomplishes this broad role is poorly understood. We identified genes
Externí odkaz:
https://doaj.org/article/cfc18502f55840b1829b584fc11a6dd4
Autor:
Eric M Hill, Christian P Petersen
Publikováno v:
eLife, Vol 7 (2018)
Most animals undergo homeostatic tissue maintenance, yet those capable of robust regeneration in adulthood use mechanisms significantly overlapping with homeostasis. Here we show in planarians that modulations to body-wide patterning systems shift th
Externí odkaz:
https://doaj.org/article/6e1ae91cce194b04a635074a3e7ff5c6
Autor:
Rachel Lander, Christian P Petersen
Publikováno v:
eLife, Vol 5 (2016)
Mechanisms enabling positional identity re-establishment are likely critical for tissue regeneration. Planarians use Wnt/beta-catenin signaling to polarize the termini of their anteroposterior axis, but little is known about how regeneration signalin
Externí odkaz:
https://doaj.org/article/96819f4f44a3480fa30c462434a8c837
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004452 (2014)
Mechanisms that enable injury responses to prompt regenerative outgrowth are not well understood. Planarians can regenerate essentially any tissue removed by wounding, even after decapitation, due to robust regulation of adult pluripotent stem cells
Externí odkaz:
https://doaj.org/article/9fb39c43a4884eda8f145ab1505de2b6
Adult regeneration restores patterning of orthogonal body axes after damage in a post-embryonic context. Planarians regenerate using distinct body-wide signals primarily regulating each axis dimension: anteroposterior Wnts, dorsoventral BMP, and medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1090ec08f1dd74e70ed8cd8c92f281f
https://doi.org/10.1101/2023.01.10.523528
https://doi.org/10.1101/2023.01.10.523528
Autor:
Christian P. Petersen
Publikováno v:
Current Topics in Developmental Biology ISBN: 9780128201671
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2971bee7a8fc8e147a0a552fdb9d5201
https://doi.org/10.1016/bs.ctdb.2023.01.007
https://doi.org/10.1016/bs.ctdb.2023.01.007
Autor:
Erik G. Schad, Christian P. Petersen
Integration of positional information across body axes is likely critical for whole-body regeneration to define the territories of missing tissue in three dimensions with fidelity. The body-wall musculature in planarians expresses patterning factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27c7684b9d41c0a970c55daed04dcc5a
https://doi.org/10.1101/2022.08.31.506052
https://doi.org/10.1101/2022.08.31.506052
Autor:
Erik G. Schad, Christian P. Petersen
The complexity of cell types and states revealed by single-cell RNAseq atlases presents a challenge for the systematic analysis of fate determinants using traditional screening methodologies. Differentiation in the planarian Schmidtea mediterranea ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7628bf5c224951103046669bfc322e7d
https://doi.org/10.1101/2022.08.29.505550
https://doi.org/10.1101/2022.08.29.505550