Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christian Pütz"'
Autor:
Juliane Tschuck, Lea Theilacker, Ina Rothenaigner, Stefanie A. I. Weiß, Banu Akdogan, Van Thanh Lam, Constanze Müller, Roman Graf, Stefanie Brandner, Christian Pütz, Tamara Rieder, Philippe Schmitt-Kopplin, Michelle Vincendeau, Hans Zischka, Kenji Schorpp, Kamyar Hadian
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Ferroptosis is a regulated cell death modality that occurs upon iron-dependent lipid peroxidation. Recent research has identified many regulators that induce or inhibit ferroptosis; yet, many regulatory processes and networks remain to be el
Externí odkaz:
https://doaj.org/article/c8879d0735a7477fa4fa2036c2269a28
Autor:
Juliane Tschuck, Lea Theilacker, Ina Rothenaigner, Stefanie A. I. Weiß, Banu Akdogan, Constanze Müller, Roman Graf, Stefanie Brandner, Christian Pütz, Tamara Rieder, Philippe Schmitt-Kopplin, Hans Zischka, Kenji Schorpp, Kamyar Hadian
ObjectiveFerroptosis is a regulated cell death modality that occurs upon iron-dependent lipid peroxidation. The recent decade of research has uncovered many regulators driving ferroptosis as well as cellular gatekeepers preventing ferroptosis. Yet, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ecec75cdce1cda64eeb536fc22db3b6
https://doi.org/10.1101/2022.10.07.511245
https://doi.org/10.1101/2022.10.07.511245
Autor:
Dominik Klein, Brigitte Semder, Winfried Kessler, Wolfgang Gries, Christian Pütz, A. Langsch, W. Kirchinger, X. Wurzenberger, Rainer Otter, Johannes G. Filser, A.K.E. Gallien
Publikováno v:
Toxicol. Lett. 294, 105-115 (2018)
Di-(2-propylheptyl) phthalate (DPHP) is used as a plasticizer for polyvinyl chloride products. A tolerable daily intake of DPHP of 0.2 mg/kg body weight has been derived from rat data. Because toxicokinetic data of DPHP in humans were not available,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be031e9ce69d21d59018c5de499ea0d1
https://pubmed.ncbi.nlm.nih.gov/30125883
https://pubmed.ncbi.nlm.nih.gov/30125883
Autor:
Winfried Kessler, Dominik Klein, Johannes G. Filser, Rainer Otter, Brigitte Semder, J. Lichtmannegger, Christian Pütz
Publikováno v:
Toxicol. Lett. 259, 80-86 (2016)
Di-(2-propylheptyl) phthalate (DPHP) does not act as a reproductive toxicant or endocrine disruptor in contrast to other phthalates. Considering adverse effects of phthalates to be linked to their metabolism, it was the aim of the present study to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb475929f91b7079526ea86eeb74d1d
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=49169
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=49169
Autor:
Wolfgang Völkel, Christian Pütz, Winfried Kessler, Dominik Klein, Wanwiwa Numtip, Johannes G. Filser, Elcim Seckin, Hermann Fromme, György A. Csanády
Publikováno v:
Toxicology and Applied Pharmacology. 264:284-291
The plasticizer di(2-ethylhexyl) phthalate (DEHP) is suspected to induce antiandrogenic effects in men via its metabolite mono(2-ethylhexyl) phthalate (MEHP). However, there is only little information on the kinetic behavior of DEHP and its metabolit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cba98b52c32c874c2a5f4a275739346
https://doi.org/10.1016/j.taap.2012.08.009
https://doi.org/10.1016/j.taap.2012.08.009
Autor:
Dominik Klein, György A. Csanády, Nadine Richter, Helmut Pankratz, Qiang Li, Christian Pütz, Winfried Kessler, Johannes G. Filser
Publikováno v:
Toxicological Sciences
Ethylene (ET) is metabolized in mammals to the carcinogenic ethylene oxide (EO). Although both gases are of high industrial relevance, only limited data exist on the toxicokinetics of ET in mice and of EO in humans. Metabolism of ET is related to cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f64ac4521a83d57d29f9d36fb2ad146
https://doi.org/10.1093/toxsci/kfr194
https://doi.org/10.1093/toxsci/kfr194
Autor:
A. Langsch, Christian Pütz, W. Kirchinger, Johannes G. Filser, A.K.E. Gallien, Winfried Kessler, Rainer Otter, Brigitte Semder, X. Wurzenberger, Dominik Klein, Wolfgang Gries
Publikováno v:
Toxicol. Lett. 296, 105 (2018)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a905bbd953b7885af03b0c01d9d0f4af
https://doi.org/10.1016/j.toxlet.2018.08.007
https://doi.org/10.1016/j.toxlet.2018.08.007
Autor:
Thomas H. Faller, György A. Csanády, James A. Swenberg, Lynn H. Pottenger, Dan Segerbäck, Melva N. Ríos-Blanco, Johannes G. Filser, Moung S. Lee, Christian Pütz, Siv Osterman-Golkar, P.E. Kreuzer, Winfried Kessler
Publikováno v:
Toxicological Sciences. 83:177-189
High concentrations of propylene oxide (PO) induced inflammation in the respiratory nasal mucosa (RNM) of rodents. Concentrations > or =300 ppm caused nasal tumors. In order to investigate if glutathione depletion could be relevant for these effects,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2380b32adf761622f28ddc702426ca05
https://doi.org/10.1093/toxsci/kfi006
https://doi.org/10.1093/toxsci/kfi006
Autor:
P.E. Kreuzer, B. Denk, Michael L. Gargas, Winfried Kessler, Johannes G. Filser, C. Baur, Gy.A. Csanády, Christian Pütz
Publikováno v:
Toxicology and Applied Pharmacology. 165:1-26
Ethylene (ET) is a gaseous olefin of considerable industrial importance. It is also ubiquitous in the environment and is produced in plants, mammals, and humans. Uptake of exogenous ET occurs via inhalation. ET is biotransformed to ethylene oxide (EO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e177946a396b8ff69de61c6134c67e52
https://doi.org/10.1006/taap.2000.8918
https://doi.org/10.1006/taap.2000.8918
Autor:
Johannes G. Filser, Thomas H. Faller, Christian Pütz, Dominik Klein, György A. Csanády, Brigitte Semder, Qiang Li, Anna Artati, Wanwiwa Numtip, P.E. Kreuzer, Winfried Kessler, Josef Lichtmannegger, Eva Erbach
Publikováno v:
Toxicological Sciences
The gaseous olefin ethylene (ET) is metabolized in mammals to the carcinogenic epoxide ethylene oxide (EO). Although ET is the largest volume organic chemical worldwide, the EO burden in ET-exposed humans is still uncertain, and only limited data are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbacad8b63fcf72d36b03dfaf145362
https://pubmed.ncbi.nlm.nih.gov/24068676
https://pubmed.ncbi.nlm.nih.gov/24068676