Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Christian P, Whitman"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 1022-1031 (2017)
5-Halo-2-hydroxymuconates and 5-halo-2-hydroxy-2,4-pentadienoates are stable dienols that are proposed intermediates in bacterial meta-fission pathways for the degradation of halogenated aromatic compounds. The presence of the halogen raises question
Externí odkaz:
https://doaj.org/article/38aa5f36456b4a94b022769732709965
Autor:
Sarah N. Sipe, Emily B. Lancaster, Jamie P. Butalewicz, Christian P. Whitman, Jennifer S. Brodbelt
Publikováno v:
Journal of the American Chemical Society. 144:12299-12309
The recent discovery of asymmetric arrangements of trimers in the tautomerase superfamily (TSF) adds structural diversity to this already mechanistically diverse superfamily. Classification of asymmetric trimers has previously been determined using X
Autor:
Emily B. Lancaster, Wanjie Yang, William H. Johnson, Bert-Jan Baas, Yan Jessie Zhang, Christian P. Whitman
Publikováno v:
Biochemistry. 61:1136-1148
Autor:
Christian P. Whitman, Karen N. Allen
Publikováno v:
Biochemistry
Enzymes are categorized into superfamilies by sequence, structural, and mechanistic similarities. The evolutionary implications can be profound. Until the mid-1990s, the approach was fragmented largely due to limited sequence and structural data. How
Autor:
Christian P. Whitman, Bert-Jan Baas, Tamer S. Kaoud, Patricia C. Babbitt, Kaci Erwin, R. Yvette Moreno, Jake LeVieux, Marieke de Ruijter, Yan Jessie Zhang, William H. Johnson, Emily B. Lancaster, Brenda P. Medellin
Publikováno v:
Biochemistry
The tautomerase superfamily (TSF) is a collection of enzymes and proteins that share a simple β-α-β structural scaffold. Most members are constructed from a single-core β-α-β motif or two consecutively fused β-α-β motifs in which the N-termi
Autor:
Yan Jessie Zhang, Patricia C. Babbitt, Swanand Rakhade, Emily B. Lancaster, Christian P. Whitman, Shoshana D. Brown, Brenda P. Medellin
Publikováno v:
Biochemistry
Tautomerase superfamily (TSF) members are constructed from a single β−α−β unit or two consecutively joined β−α−β units. This pattern prevails throughout the superfamily consisting of more than 11,000 members where homo- or heterohexamer
Autor:
Emily B. Lancaster, William H. Johnson, Jake A. LeVieux, Haley A. Hardtke, Yan Jessie Zhang, Christian P. Whitman
Publikováno v:
Archives of Biochemistry and Biophysics. 733:109471
NahE is a hydratase-aldolase that converts o-substituted trans-benzylidenepyruvates (H, OH, or CO
Autor:
William H. Johnson, Christian P. Whitman, Kerry A. Kinney, J. Oliver Haugland, Desmond F. Lawler, Marina Montserrat Atilano Camino
Publikováno v:
Water Environment Research. 91:281-291
Laccases were studied for their ability to remove two compounds, 2-chlorophenol and sulfamethoxazole, in batch studies, both in buffered solutions and in wastewater samples from different points in a municipal water resource recovery facility. Two en
Autor:
Rebecca Davidson, Patricia C. Babbitt, Tamer S. Kaoud, Christian P. Whitman, Bert-Jan Baas, Jake LeVieux, Yan Jessie Zhang
Publikováno v:
Archives of Biochemistry and Biophysics. 636:50-56
A Pseudomonas sp. UW4 protein (UniProt K9NIA5) of unknown function was identified as similar to 4-oxalocrotonate tautomerase (4-OT)-like and cis-3-chloroacrylic acid dehalogenase (cis-CaaD)-like subgroups of the tautomerase superfamily (TSF). This pr
Autor:
Patricia C. Babbitt, Jake LeVieux, Eyal Akiva, Yan Jessie Zhang, Rebecca Davidson, Collin R. Pullara, Christian P. Whitman, Bert-Jan Baas, Benjamin J. Polacco, Gemma L. Holliday
Publikováno v:
The Journal of Biological Chemistry
The tautomerase superfamily (TSF) consists of more than 11,000 nonredundant sequences present throughout the biosphere. Characterized members have attracted much attention because of the unusual and key catalytic role of an N-terminal proline. These