Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Christian Otten"'
Autor:
Iris Löckener, Lara Vanessa Behrmann, Jula Reuter, Andrea Schiefer, Anna Klöckner, Sebastian Krannich, Christian Otten, Katja Mölleken, Satoshi Ichikawa, Achim Hoerauf, Tanja Schneider, Kenneth M. Pfarr, Beate Henrichfreise
Publikováno v:
Antibiotics, Vol 13, Iss 5, p 421 (2024)
Chlamydial infections and diseases caused by filarial nematodes are global health concerns. However, treatment presents challenges due to treatment failures potentially caused by persisting Chlamydia and long regimens against filarial infections acco
Externí odkaz:
https://doaj.org/article/92030dcf073649b2808790b4e071297e
Autor:
Jula Reuter, Christian Otten, Nicolas Jacquier, Junghoon Lee, Dominique Mengin-Lecreulx, Iris Löckener, Robert Kluj, Christoph Mayer, Federico Corona, Julia Dannenberg, Sébastien Aeby, Henrike Bühl, Gilbert Greub, Waldemar Vollmer, Scot P Ouellette, Tanja Schneider, Beate Henrichfreise
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011047 (2023)
The obligate intracellular Chlamydiaceae do not need to resist osmotic challenges and thus lost their cell wall in the course of evolution. Nevertheless, these pathogens maintain a rudimentary peptidoglycan machinery for cell division. They build a t
Externí odkaz:
https://doaj.org/article/fdf8f7a7bce540f6b36caa5585ecad53
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
The Gram-negative plant-pathogenic bacterium Xanthomonas euvesicatoria is the causal agent of bacterial spot disease in pepper and tomato plants. Pathogenicity of X. euvesicatoria depends on a type III secretion (T3S) system which translocates effect
Externí odkaz:
https://doaj.org/article/a0d2a51e56bc44dabeeadc3d6ffdf7d3
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Pathogenicity of the Gram-negative bacterium Xanthomonas campestris pv. vesicatoria depends on a type III secretion (T3S) system which translocates effector proteins into plant cells. T3S systems are conserved in plant- and animal-pathogenic bacteria
Externí odkaz:
https://doaj.org/article/1d8c180ffdfd45f88e6406e1371d0deb
Autor:
Niccolò Morè, Alessandra M. Martorana, Jacob Biboy, Christian Otten, Matthias Winkle, Carlos K. Gurnani Serrano, Alejandro Montón Silva, Lisa Atkinson, Hamish Yau, Eefjan Breukink, Tanneke den Blaauwen, Waldemar Vollmer, Alessandra Polissi
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Gram-negative bacteria have a tripartite cell envelope with the cytoplasmic membrane (CM), a stress-bearing peptidoglycan (PG) layer, and the asymmetric outer membrane (OM) containing lipopolysaccharide (LPS) in the outer leaflet. Cells must
Externí odkaz:
https://doaj.org/article/2f19b63868df4508b1af58dc5d1478a9
Autor:
Alejandro Montón Silva, Christian Otten, Jacob Biboy, Eefjan Breukink, Michael VanNieuwenhze, Waldemar Vollmer, Tanneke den Blaauwen
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The enzymes responsible for the synthesis of the peptidoglycan (PG) layer constitute a fundamental target for a large group of antibiotics. The family of β-lactam antibiotics inhibits the DD-transpeptidase (TPase) activity of the penicillin binding
Externí odkaz:
https://doaj.org/article/acb5d73a8bb447d28640b45855b62c1d
Publikováno v:
Bio-Protocol, Vol 8, Iss 6 (2018)
Peptidoglycan encases the bacterial cytoplasmic membrane to protect the cell from lysis due to the turgor. The final steps of peptidoglycan synthesis require a membrane-anchored substrate called lipid II, in which the peptidoglycan subunit is linked
Externí odkaz:
https://doaj.org/article/e463eeabf25a476c84aade7986ed1c21
Autor:
Christian Otten, Stefania De Benedetti, Ahmed Gaballah, Henrike Bühl, Anna Klöckner, Jarryd Brauner, Hans-Georg Sahl, Beate Henrichfreise
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122110 (2015)
Heterologous overexpression of foreign proteins in Escherichia coli often leads to insoluble aggregates of misfolded inactive proteins, so-called inclusion bodies. To solve this problem use of chaperones or in vitro refolding procedures are the means
Externí odkaz:
https://doaj.org/article/ea2f385b67704ddcb1b38577d55df60d
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25129 (2011)
In rod-shaped bacteria, the bacterial actin ortholog MreB is considered to organize the incorporation of cell wall precursors into the side-wall, whereas the tubulin homologue FtsZ is known to tether incorporation of cell wall building blocks at the
Externí odkaz:
https://doaj.org/article/d12933450f7747eba4a22f961e5cc0c7
Autor:
Jula Reuter, Christian Otten, Nicolas Jacquier, Junghoon Lee, Dominique Mengin-Lecreulx, Iris Löckener, Robert Kluj, Christoph Mayer, Federico Corona, Julia Dannenberg, Sébastien Aeby, Henrike Bühl, Gilbert Greub, Waldemar Vollmer, Scot P. Ouellette, Tanja Schneider, Beate Henrichfreise
The obligate intracellularChlamydiaceaedo not need to resist osmotic challenges and thus lost their cell wall in the course of evolution. Nevertheless, these pathogens maintain a rudimentary peptidoglycan machinery for cell division. They build a tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fff74a49a2d6b5bfdb3f7b11739b95
https://doi.org/10.1101/2022.11.17.516864
https://doi.org/10.1101/2022.11.17.516864