Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christian N, Nguetse"'
Autor:
Christian N. Nguetse, Ayola Akim Adegnika, Tsiri Agbenyega, Bernhards R. Ogutu, Sanjeev Krishna, Peter G. Kremsner, Thirumalaisamy P. Velavan
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background The Plasmodium falciparum multidrug resistance 1 (PfMDR1), P. falciparum Ca2+-ATPase (PfATP6) and Kelch-13 propeller domain (PfK13) loci are molecular markers of parasite susceptibility to anti-malarial drugs. Their frequency dist
Externí odkaz:
https://doaj.org/article/b9eb2a0e5e4c496985dec5a6d4f4045f
Autor:
Felix Koukouikila-Koussounda, Sankarganesh Jeyaraj, Christian N. Nguetse, Charles Nchotebah Nkonganyi, Kossiwa Clarisse Kokou, Mandingha K. Etoka-Beka, Francine Ntoumi, Thirumalaisamy P. Velavan
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-7 (2017)
Abstract Background Resistance to anti-malarial drugs hinders efforts on malaria elimination and eradication. Following the global spread of chloroquine-resistant parasites, the Republic of Congo adopted artemisinin-based combination therapy (ACT) in
Externí odkaz:
https://doaj.org/article/35b9427bb75349c4a5f957df450737ed
Autor:
Thaisa Lucas Sandri, Selorme Adukpo, Dao Phuong Giang, Christian N Nguetse, Fabiana Antunes Andrade, Hoang van Tong, Nguyen Linh Toan, Le Huu Song, Preetham Elumalai, Kumarasamy Thangaraj, Vijaya Lakshmi Valluri, Francine Ntoumi, Christian G Meyer, Iara Jose de Messias Reason, Peter G Kremsner, Thirumalaisamy P Velavan
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0175973 (2017)
BACKGROUND:Pathogens exert selective pressure which may lead to substantial changes in host immune responses. The human complement receptor type 1 (CR1) is an innate immune recognition glycoprotein that regulates the activation of the complement path
Externí odkaz:
https://doaj.org/article/0a66efb042864525bd2b1a5c11bfc88b
Autor:
Natasha Purington, Emily R. Ebel, Bikash Shakya, Marilou Tétard, Christian N. Nguetse, Elizabeth S. Egan, Thirumalaisamy P. Velavan, Peter G. Kremsner
Publikováno v:
Proceedings of the National Academy of Sciences. 117:9074-9081
Malaria caused by the apicomplexan parasite Plasmodium falciparum has served as a strong evolutionary force throughout human history, selecting for red blood cell polymorphisms that confer innate protection against severe disease. Recently, gain-of-f
Autor:
Christian N, Nguetse, Natasha, Purington, Emily R, Ebel, Bikash, Shakya, Marilou, Tetard, Peter G, Kremsner, Thirumalaisamy P, Velavan, Elizabeth S, Egan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The clinical presentation of Plasmodium falciparum malaria as severe versus uncomplicated is influenced by host genetic factors. Recently, a gain-of-function mutation in the mechanosensitive ion channel PIEZO1 was shown to protect mice a
Autor:
Charles Nchotebah, Olusola Ojurongbe, Johnson A Ojo, Thirumalaisamy P. Velavan, Moses Nkechukwu Ikegbunam, Christian Meyer, Christian N. Nguetse, Bolaji N. Thomas
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 98:667-676
The genetic diversity of glutamate-rich protein (GLURP) R2 region in Plasmodium falciparum isolates collected before and 12 years after the introduction of artemisinin combination treatment of malaria in Osogbo, Osun State, Nigeria, was compared in t
Autor:
Bolaji N. Thomas, Taiwo Adetola Ojurongbe, Christian N. Nguetse, S A Fayemiwo, Christian Meyer, Olusola Ojurongbe, Catherine O. Falade, Thirumalaisamy P. Velavan
Publikováno v:
Pathogens and Global Health. 112:86-92
This study assesses the prevalence of asymptomatic Plasmodium falciparum parasitemia positivity and P. falciparum dihydrofolate reductase (pfdhfr) mutations in parasite isolates among pregnant women in Southwest Nigeria. Plasmodium falciparum parasit
Autor:
Elizabeth S. Egan, Christian N. Nguetse, Thirumalaisamy P. Velavan, Natasha Purington, Bikash Shakya, Emily R. Ebel, Peter G. Kremsner
Malaria caused by the Apicomplexan parasite Plasmodium falciparum has served as a strong evolutionary force throughout human history, selecting for red blood cell polymorphisms that confer innate protection against severe disease. Recently, gain-of-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b6ae507579e15e43e0c2b392862ff8
https://doi.org/10.1101/691253
https://doi.org/10.1101/691253
Publikováno v:
Encyclopedia of Malaria ISBN: 9781461487579
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e5285dfb713c4fd11d30cc462aa2332
https://doi.org/10.1007/978-1-4614-8757-9_139-1
https://doi.org/10.1007/978-1-4614-8757-9_139-1
Autor:
Bolaji N. Thomas, Thirumalaisamy P. Velavan, David Nderu, Christian N. Nguetse, Olusola Ojurongbe, Catherine O. Falade, Roland I Funwei
Publikováno v:
Acta tropica. 196
Prompt diagnosis and appropriate treatment of malaria remain the hallmark for reducing malaria-related mortality in high transmission areas. Plasmodium falciparum histidine-rich protein2 (PfHRP2) based rapid diagnostic tests (RDT) play a vital role i