Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Christian Muhl"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 16, Iss , Pp 543-550 (2018)
Nanoparticles coated with hydrophilic polymers often show a reduction in unspecific interactions with the biological environment, which improves their biocompatibility. The molecular determinants of this reduction are not very well understood yet, an
Externí odkaz:
https://doaj.org/article/2d98f77e0054418e81d74e4345af6e40
Publikováno v:
Biomacromolecules
Biomacromolecules, 22(5), 2171-2180. American Chemical Society (ACS)
Biomacromolecules, 22(5), 2171-2180. American Chemical Society (ACS)
Secondary structure formation differentiates polypeptides from most of the other synthetic polymers, and the transitions from random coils to rod-like α-helices or β-sheets represent an additional parameter to direct self-assembly and the morpholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e414bfd1c7f7cd4e673c24b1b00b89bf
https://doi.org/10.1021/acs.biomac.1c00253
https://doi.org/10.1021/acs.biomac.1c00253
Autor:
Paul Eckhardt, Christian Muhl, Jonathan Groß, Matthias Barz, Lydia Zengerling, Till Opatz, Pol Besenius
Publikováno v:
Polymer Chemistry. 11:6919-6927
The ring-opening polymerization (ROP) of N-carboxy anhydrides (NCAs) is mostly divided into two classes: NCAs of α-substituted amino acids and N-methylated NCAs of α-unsubstituted glycine derivatives (NNCAs). The use of both monomer types offers di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed0e24f99da71150b3a8df0b73ba2786
https://doi.org/10.1039/d0py01055c
https://doi.org/10.1039/d0py01055c
Autor:
Benjamin Weber, Christian Muhl, Kerstin Johann, Olga Schäfer, Christine Seidl, Alexander Birke, Regina Holm, Dieter Schollmeyer, Matthias Barz
Publikováno v:
Tetrahedron Letters. 60:272-275
The need for a scalable synthesis of not sequence defined polypeptides as biomaterials is met by the ring-opening polymerization of α-amino acid N-carboxyanhydrides (NCAs). Even though this polymerization technique appears straight forward, it holds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ba52f4be21ea881f805d5bece855cf
https://doi.org/10.1016/j.tetlet.2018.12.028
https://doi.org/10.1016/j.tetlet.2018.12.028
Publikováno v:
High Performance Computing in Science and Engineering '19 ISBN: 9783030667917
Hydrophilic polymers are being investigated as possible coating agents for therapeutic nanoparticles because of their capacity to reduce immune response and increase circulation life time. The mechanism of action of these coatings is not well underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8e093a25506aab71b7a72fbdbf33e74
https://doi.org/10.1007/978-3-030-66792-4_4
https://doi.org/10.1007/978-3-030-66792-4_4
Autor:
Rabea Möller, Katharina Kaiser, Ulrich Baulain, Björn Petersen, Carsten Detering, Mahnaz Ekhlasi-Hundrieser, Richard Zimmermann, Christian Mühlfeld, Mario von Depka Prondzinski, Christiane Pfarrer, Stefanie Lehner
Publikováno v:
Hemato, Vol 5, Iss 1, Pp 48-65 (2024)
Pregnancy and the oestrus cycle are challenging for female patients suffering from von Willebrand disease (VWD). Therefore, our study aimed to investigate the changes in von Willebrand factor (VWF) and factor VIII (FVIII) during pregnancy and the oes
Externí odkaz:
https://doaj.org/article/8e2d7800fbb34ffabb00cd48af07478c
Autor:
Sarah Piechowski, Lennard J. Kalkoffen, Sibylle Benderoth, Oliver T. Wolf, Jörn Rittweger, Daniel Aeschbach, Christian Mühl
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Sleep deprivation and circadian rhythm disruptions are highly prevalent in shift workers, and also among astronauts. Resulting sleepiness can reduce cognitive performance, lead to catastrophic occupational events, and jeopardize space missio
Externí odkaz:
https://doaj.org/article/24c82cb8282a4bf7b3eeb56271187623
Publikováno v:
Macromolecules. 51:8188-8196
Homocysteine and cysteine are the only natural occurring amino acids that are capable of disulfide bond formations in peptides and proteins. The chemoselective formation of asymmetric disulfide bonds, however, is chemically challenging and requires a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c067381f481aaa1c16976c77dbf449
https://doi.org/10.1021/acs.macromol.8b01442
https://doi.org/10.1021/acs.macromol.8b01442
Autor:
Matthias Barz, Jörg Huwyler, Christian Muhl, Regine Süss, Stefan Bleher, Sabine Barnert, Jonas Buck, Sandro Sieber, Dominik Witzigmann
Publikováno v:
SMALL, 15(50), 1904716. WILEY-V C H VERLAG GMBH
SMALL
SMALL
Circulation lifetime is a crucial parameter for a successful therapy with nanoparticles. Reduction and alteration of opsonization profiles by surface modification of nanoparticles is the main strategy to achieve this objective. In clinical settings,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c2099e717d12f326eb1eb36e191c57
https://hdl.handle.net/1887/3147120
https://hdl.handle.net/1887/3147120
The use of PEGylated lipids for the synthesis of stealth liposomes and lipid formulations for nucleic acid delivery has promoted the development of nanoparticle based drugs for cancer therapy, and chronic diseases. Moreover, several other nanomedicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23153ac2809e6f9b53460e55ccf89d00
http://hdl.handle.net/1887/3201487
http://hdl.handle.net/1887/3201487