Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christian Miculka"'
Autor:
Bodo Lachmann, Simon Eppacher, Christian Miculka, Christian R. Noe, Peter Richter, Jerome Freissmuth
Publikováno v:
Life, Vol 3, Iss 3, Pp 486-501 (2013)
Experiments will be presented and reviewed to support the hypothesis that the intrinsic reactivity of formaldehyde may lead to the formation of a rather comprehensive set of defined biomolecules, including D-glucose, thus fostering concepts of evolut
Externí odkaz:
https://doaj.org/article/7ac96c50d1f54c04bbb36885837e2664
Autor:
Thorsten Meyer, Harald Sekljic, Stefan Fuchs, Heiko Bothe, Dieter Schollmeyer, Christian Miculka
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 3, Iss 1, p e357 (2009)
BACKGROUND: Praziquantel (PZQ) is the drug compound of choice in the control and treatment of schistosomiasis. PZQ is administered as a racemate, i. e. 1ratio1 mixture of enantiomers. The schistosomicidal activity arises from one PZQ-enantiomer, wher
Externí odkaz:
https://doaj.org/article/9f27118e51254bf0a43ee17a6c7afe73
Publikováno v:
Helvetica Chimica Acta. 95:845-851
In this article, we present the synthesis of a series of oligo(oxymethylenes) capped with 1-phenylethanol and MeOH. The anionic condition affords enantiomerically pure oligo(oxymethylene) oligomers, while the cationic oligomerization leads to a racem
Autor:
Anja R. Heckeroth, Frank Seeber, Christian Miculka, Stefan Baumeister, Paul Selzer, Thorsten Meyer, Hon Q. Tran
Publikováno v:
Apicomplexan Parasites: Molecular Approaches toward Targeted Drug Development
Autor:
Michael R. Linder, Michael Najdrowski, Arwid Daugschies, Dieter Schollmeyer, Anja R. Heckeroth, Christian Miculka
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:4140-4143
The trans-enantiomers of the commercially important anti-protozoal compound Halofuginone have been prepared and characterized, and the absolute configuration was assigned by X-ray crystallography. The activity of both enantiomers against Cryptosporid
Autor:
Christian Miculka, Jan W. Bats
Publikováno v:
Helvetica Chimica Acta. 89:218-230
In the context of Eschenmoser's work on pyranosyl-RNA (‘p-RNA’), we investigated the synthesis and base-pairing properties of the 5-methylisocytidine derivative. The previously determined clear-cut restrictions of base-pairing modes of p-RNA had
Autor:
Stefan Pitsch, Ramanarayanan Krishnamurthy, Christian Miculka, Albert Eschenmoser, Mark Minton, Norbert Windhab
Publikováno v:
Angewandte Chemie. 108:1619-1623
Autor:
Karin Dungler, Max Knollmüller, Christian Miculka, Ernst Wagner, Peter Ettmayer, Christian R. Noe
Publikováno v:
Chemische Berichte. 127:887-892
Chiral Lactols, XI. - A Method for the Determination of the Absolute Configuration of Chiral Alkanols Chiral secondary alcohols which are protected with the enantiomerically pure lactol 1 or 2 show significant differences in 13C-chemical shifts aroun
Publikováno v:
Chemische Berichte. 127:359-365
Stereoelectronic Effects and Chiral Recognition, I. — Diastereoselective Formation of Ethers from Alkylarylcarbinols Acid-catalysed etherification of various alkylarylcarbinols 1 leads to a mixture of diastereomeric products 2 and 3. As found in th
Autor:
Michael L. Berger, Trevor Newton, Christina Mertens, Harald Sekljic, Jörg Cramer, Christian Miculka, Jörg Schröder, Michael Hinz
Publikováno v:
Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fae92e10db63cbe539acea1b3c6765d
https://doi.org/10.1002/9783527626816.ch9
https://doi.org/10.1002/9783527626816.ch9