Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Christian Michel, Zwaan"'
Autor:
Kirsten A. Thus, Hester A. de Groot-Kruseman, Pauline Winkler-Seinstra, Marta Fiocco, Heidi Segers, Cor van den Bos, Inge M. van der Sluis, Wim J.E. Tissing, Margreet A. Veening, Christian Michel Zwaan, Cornelis M. van Tilburg, Rob Pieters, Marc Bierings
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Infections lead to substantial morbidity during treatment of acute lymphoblastic leukemia (ALL) in which the adaptive immune system gets severely affected, leading to declining serum immunoglobulin levels. The aim of this trial was to investigate whe
Externí odkaz:
https://doaj.org/article/634bb1c123c8458d9d413f68bd657421
Autor:
Stephanie Sembill, Maria Ampatzidou, Sonali Chaudhury, Michael Dworzak, Krzysztof Kalwak, Axel Karow, Alexander Kiani, Manuela Krumbholz, Maaike Luesink, Nora Naumann-Bartsch, Barbara De Moerloose, Michael Osborn, Kirk R. Schultz, Petr Sedlacek, Fiorina Giona, Christian Michel Zwaan, Hiroyuki Shimada, Birgitta Versluijs, Frederic Millot, Nobuko Hijiya, Meinolf Suttorp, Markus Metzler
Publikováno v:
LEUKEMIA
Treatment of chronic myeloid leukemia has improved significantly with the introduction of tyrosine kinase inhibitors (TKIs), and treatment guidelines based on numerous clinical trials are available for chronic phase disease. However for CML in the bl
Autor:
Priscilla Wander, Susan T. C. J. M. Arentsen-Peters, Kirsten S. Vrenken, Sandra Mimoso Pinhanҫos, Bianca Koopmans, M. Emmy M. Dolman, Luke Jones, Patricia Garrido Castro, Pauline Schneider, Mark Kerstjens, Jan J. Molenaar, Rob Pieters, Christian Michel Zwaan, Ronald W. Stam
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 638 (2022)
KMT2A-rearranged acute lymphoblastic leukemia (ALL) in infants (KMT2A-rearranged infant ALL patient samples (n = 2). The most effective drugs were then tested on non-leukemic whole bone marrow samples (n = 2) to select drugs with a favorable therapeu
Externí odkaz:
https://doaj.org/article/7815cb20aae54d3d99175e3e8348e9d7
Autor:
Lucas Moreno, Steven G. DuBois, Julia Glade Bender, Audrey Mauguen, Nick Bird, Vickie Buenger, Michela Casanova, François Doz, Elizabeth Fox, Lia Gore, Douglas S. Hawkins, Shai Izraeli, David T.W. Jones, Pamela R. Kearns, Jan J. Molenaar, Karsten Nysom, Stefan Pfister, Gregory Reaman, Malcolm Smith, Brenda Weigel, Gilles Vassal, Christian Michel Zwaan, Xavier Paoletti, Alexia Iasonos, Andrew D.J. Pearson
Publikováno v:
Scientia
PURPOSE There is an increasing need to evaluate innovative drugs for childhood cancer using combination strategies. Strong biological rationale and clinical experience suggest that multiple agents will be more efficacious than monotherapy for most di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cfed0b001a0a7bb4dbc82e8b4ec2a0
https://hdl.handle.net/11351/9922
https://hdl.handle.net/11351/9922
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
XLS file - 48K, Sources of Small-Molecule Kinase Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0413283c94e508f27580b33c39b2e7
https://doi.org/10.1158/0008-5472.22396923.v1
https://doi.org/10.1158/0008-5472.22396923.v1
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
XLS file - 552K, 151 Patient Drug Curve Raw Data Points
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb94612032623b4a3cb5ba3e929bf3c9
https://doi.org/10.1158/0008-5472.22396935.v1
https://doi.org/10.1158/0008-5472.22396935.v1
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
XLS file - 114K, Kinase Inhibitor Gene Targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4a89e6382912368a7b1439a3009483
https://doi.org/10.1158/0008-5472.22396944
https://doi.org/10.1158/0008-5472.22396944
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
XLS file - 132K, 151 Patient IC50s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc86b81e6f00e4bb60a8cc0ca2414aca
https://doi.org/10.1158/0008-5472.22396938
https://doi.org/10.1158/0008-5472.22396938
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
XLS file - 73K, Cumulative Gene Target Scores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c449eabe4e1634d447b7d1da67cb52
https://doi.org/10.1158/0008-5472.22396926
https://doi.org/10.1158/0008-5472.22396926
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
PDF file - 378K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7aabd591ea531112356ae131c143a8
https://doi.org/10.1158/0008-5472.22396920
https://doi.org/10.1158/0008-5472.22396920