Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Christian Merten"'
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-11 (2021)
Chiral molecular recognition is critical in many natural processes, but probing the conformational landscape of chiral aromatic systems can be challenging. Here, high-resolution broadband rotational spectroscopy data is combined with quantum chemical
Externí odkaz:
https://doaj.org/article/e913320618b24481a17762823cbd43bf
Autor:
Lais S Morais, Renata G Dusi, Daniel P Demarque, Raquel L Silva, Lorena C Albernaz, Sônia N Báo, Christian Merten, Luciana M R Antinarelli, Elaine S Coimbra, Laila S Espindola
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241855 (2020)
Leishmaniasis is a disease impacting public health worldwide due to its high incidence, morbidity and mortality. Available treatments are costly, lengthy and toxic, not to mention the problem of parasite resistance. The development of alternative tre
Externí odkaz:
https://doaj.org/article/f8248aafa4a74176a3eb4767ecc9f7cb
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The 3-thiazolidine ring, a pharmaceutically interesting cyclic structural element found e.g. in some antibiotics, is hard to obtain via currently used approaches. Here, the authors developed a straightforward method to efficiently synthesize a variet
Externí odkaz:
https://doaj.org/article/70159b5ac5fd47009fa14f6aef22e6b2
Publikováno v:
Marine Drugs, Vol 18, Iss 11, p 581 (2020)
Brown alga Bifurcaria bifurcata is a prolific source of bioactive acyclic (linear) diterpenes with high structural diversity. In the continuation of our investigations on Irish brown algae, we undertook an in-depth chemical study on the n-hexanes and
Externí odkaz:
https://doaj.org/article/9df9ec938cf5427e9178673225a2bade
Publikováno v:
Marine Drugs, Vol 15, Iss 8, p 245 (2017)
Linear diterpenes that are commonly found in brown algae are of high chemotaxonomic and ecological importance. This study reports bifurcatriol (1), a new linear diterpene featuring two stereogenic centers isolated from the Irish brown alga Bifurcaria
Externí odkaz:
https://doaj.org/article/2fe813e2a10744e086b0db51d515c100
Publikováno v:
Organic & Biomolecular Chemistry. 21:4422-4428
The stereoselectivity of the title reaction is governed by the substitution pattern within the allene substrate and by the choice of Lewis acid catalyst allowing a facile access to bicyclo[2.2.1]heptenes with an exocyclic double bond.
Publikováno v:
Physical Chemistry Chemical Physics. 25:3343-3353
The inclusion of anharmonicity in vibrational spectral analyis remains associated to small molecular systems with up to a dozen of atoms, with half a dozen of non-hydrogen atoms, typically thesize of propylene oxide. One may see two reasons for this:
Publikováno v:
Organic Letters. 24:6903-6907
The absolute configuration of the polyketide natural product (-)-enterocin was established by two independent approaches. In the first approach, synthetic enterocin with a defined configuration was compared to the natural product. While identical in
Autor:
Jie Liu, Shubhadip Mallick, Yusheng Xie, Corentin Grassin, Belén Lucas, Beate Schölermann, Axel Pahl, Rebecca Scheel, Carsten Strohmann, Christoph Protzel, Thorsten Berg, Christian Merten, Slava Ziegler, Herbert Waldmann
Publikováno v:
Angewandte Chemie International Edition. 62
Autor:
Kevin Scholten, Christian Merten
Publikováno v:
Physical Chemistry Chemical Physics. 24:3611-3617
Based on an extensive conformational sampling, VCD spectroscopy enables the characterization of the dominant conformers and solvation states of the title peptide in DMSO-d6 solution.