Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Christian Marx"'
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-6 (2024)
Abstract Background Tenodesis of the long head of the biceps tendon is frequently performed in shoulder surgery, and all-suture anchors have become more popular as fixation methods. However, uncertainty still exists regarding the ultimate load to fai
Externí odkaz:
https://doaj.org/article/514dd13d86764f3387364ef32c03dde2
Autor:
Stephanie Geyer, Pavel Kadantsev, Daniel Bohnet, Christian Marx, Romed P. Vieider, Sepp Braun, Sebastian Siebenlist, Sebastian Lappen
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Objective Partial ruptures of the distal triceps tendon are usually treated surgically from a size of > 50% tendon involvement. The aim of this study was to compare the ultimate load to failure of intact triceps tendons with partially ruptur
Externí odkaz:
https://doaj.org/article/074dfd1ea9a3496bbf6b991a4595a43c
Autor:
Christian Marx, Jürgen Sonnemann, Oliver D. K. Maddocks, Lisa Marx-Blümel, Mandy Beyer, Doerte Hoelzer, René Thierbach, Claudia Maletzki, Michael Linnebacher, Thorsten Heinzel, Oliver H. Krämer
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background Metabolic adaptations can allow cancer cells to survive DNA-damaging chemotherapy. This unmet clinical challenge is a potential vulnerability of cancer. Accordingly, there is an intense search for mechanisms that modulate cell met
Externí odkaz:
https://doaj.org/article/b54be1c1c57b4247a2dde92cec4134b4
Optical Measurement of Ligament Strain: Opportunities and Limitations for Intraoperative Application
Publikováno v:
Sensors, Vol 23, Iss 17, p 7487 (2023)
A feasible and precise method to measure ligament strain during surgical interventions could significantly enhance the quality of ligament reconstructions. However, all existing scientific approaches to measure in vivo ligament strain possess at leas
Externí odkaz:
https://doaj.org/article/6ba8536a2b1e412f897fc3ded8ead1ef
Autor:
Alena Gschwind, Christian Marx, Marie D. Just, Paula Severin, Hannah Behring, Lisa Marx-Blümel, Sabine Becker, Linda Rothenburger, Martin Förster, James F. Beck, Jürgen Sonnemann
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-20 (2022)
Abstract Background Autophagy plays an essential role in maintaining cellular homeostasis and in the response to cellular stress. Autophagy is also involved in cell cycle progression, yet the relationship between these processes is not clearly define
Externí odkaz:
https://doaj.org/article/80c924d65a344261b247c7fdff57d0f2
Autor:
Christian Marx, Jürgen Sonnemann, Mandy Beyer, Oliver D. K. Maddocks, Sergio Lilla, Irene Hauzenberger, Andrea Piée‐Staffa, Kanstantsin Siniuk, Suneetha Nunna, Lisa Marx‐Blümel, Martin Westermann, Tobias Wagner, Felix B. Meyer, René Thierbach, Christina S. Mullins, Said Kdimati, Michael Linnebacher, Francesco Neri, Thorsten Heinzel, Zhao‐Qi Wang, Oliver H. Krämer
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3404-3429 (2021)
Late‐stage colorectal cancer (CRC) is still a clinically challenging problem. The activity of the tumor suppressor p53 is regulated via post‐translational modifications (PTMs). While the relevance of p53 C‐terminal acetylation for transcription
Externí odkaz:
https://doaj.org/article/0b74c48fb69942fab1d217753fe500f2
Autor:
Simone Di Sanzo, Katrin Spengler, Anja Leheis, Joanna M. Kirkpatrick, Theresa L. Rändler, Tim Baldensperger, Therese Dau, Christian Henning, Luca Parca, Christian Marx, Zhao-Qi Wang, Marcus A. Glomb, Alessandro Ori, Regine Heller
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Accumulation of advanced glycation end products such as carboxymethyllysine (CML) has been associated with aging but their molecular roles are largely unclear. Here, the authors use proteomics to identify CML sites and show that CML formation affects
Externí odkaz:
https://doaj.org/article/2a95d56d607f461daa73332371e24e27
Autor:
Lisa Marx-Blümel, Christian Marx, Jürgen Sonnemann, Frank Weise, Jörg Hampl, Jessica Frey, Linda Rothenburger, Emilio Cirri, Norman Rahnis, Philipp Koch, Marco Groth, Andreas Schober, Zhao-Qi Wang, James F. Beck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Hematopoietic stem cell (HSC) transplantation is successfully applied since the late 1950s. However, its efficacy can be impaired by insufficient numbers of donor HSCs. A promising strategy to overcome this hurdle is the use of an advanced e
Externí odkaz:
https://doaj.org/article/c3458d44a6a74132a128e0b81a5e3c4c
Autor:
Murat Kirtay, Josefine Sell, Christian Marx, Holger Haselmann, Mihai Ceanga, Zhong-Wei Zhou, Vahid Rahmati, Joanna Kirkpatrick, Katrin Buder, Paulius Grigaravicius, Alessandro Ori, Christian Geis, Zhao-Qi Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Ataxia Telangiectasia and Rad3-related (ATR) is a key regulator of replication stress response; yet, mutations within the ATR gene cause human ATR-Seckel Syndrome associated with microcephaly and intellectual disability. Here, the authors show neuron
Externí odkaz:
https://doaj.org/article/2dd9c267ac854fe5bdc2ba175941b03b
Autor:
Christian Marx, Marc U. Schaarschmidt, Joanna Kirkpatrick, Lisa Marx-Blümel, Melisa Halilovic, Martin Westermann, Doerte Hoelzer, Felix B. Meyer, Yibo Geng, Katrin Buder, Hauke M. Schadwinkel, Kanstantsin Siniuk, Sabine Becker, René Thierbach, James F. Beck, Jürgen Sonnemann, Zhao-Qi Wang
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Introduction Ewing's sarcoma is an aggressive childhood malignancy whose outcome has not substantially improved over the last two decades. In this study, combination treatments of the HSP90 inhibitor AUY922 with either the ATR inhibitor VE82
Externí odkaz:
https://doaj.org/article/d8fb96d8e11f4e79b641bb5a2f9a1a6f