Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Christian Margeta"'
Autor:
Sophie Brunner-Ziegler, Georgiana-Aura Giurgea, Christine Mannhalter, Martin Brunner, Christian Margeta, Raute Sunder-Plassmann, Renate Koppensteiner, Alexandra Hammer
Publikováno v:
Gene. 526:295-298
Background In recent years reduced bone mineral density (BMD) and osteoporosis have become major public health problems. Single nucleotide polymorphisms (SNPs) in the cytochrome P450 2C9 (CYP2C9) gene influence the response to oral anticoagulant drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2741bb0e7c4c5921a418388ccc98ca
https://doi.org/10.1016/j.gene.2013.05.026
https://doi.org/10.1016/j.gene.2013.05.026
Autor:
Michael Schwameis, Oliver Schlager, Renate Koppensteiner, Michael E. Gschwandtner, Christoph Domenig, Ilda Lilaj, Andrea Willfort-Ehringer, Sonja Zehetmayer, Georgiana-Aura Giurgea, Christian Margeta
Publikováno v:
Wiener klinische Wochenschrift. 124:769-774
Carotid duplex ultrasonography is the prime investigation used to grade carotid artery stenosis in clinical routine. We compared the carotid ultrasound (US) scans performed externally with our results. This retrospective study included 288 patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec278ca2420377181ba8dc1e7bf3ec05
https://doi.org/10.1007/s00508-012-0259-1
https://doi.org/10.1007/s00508-012-0259-1
Autor:
Aura Giurgea, Sonja Zehetmayer, Edith Schober, Alexandra Hammer, Oliver Schlager, Renate Koppensteiner, Birgit Rami-Merhar, Andrea Willfort-Ehringer, Maria Fritsch, Katrin Nagl, Gerit-Holger Schernthaner, Michael E. Gschwandtner, Christian Margeta
Publikováno v:
Diabetologia. 55:1633-1640
Deterioration of microvascular function may have an early onset in individuals with type 1 diabetes mellitus. We hypothesised that microvascular autoregulation is impaired in children with type 1 diabetes and can be detected non-invasively by postocc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f4667b471e34051950ebe0406936ca
https://doi.org/10.1007/s00125-012-2502-8
https://doi.org/10.1007/s00125-012-2502-8
Autor:
T. Maca, Abdolreza Rezaie-Majd, Mehrdad Baghestanian, Robert A. Bucek, Mahmood Manavi, Erich Minar, Christian Margeta, Aura G Giurgea, Reza Afarideh
Publikováno v:
Journal of Cardiovascular Pharmacology. 47:30-36
Vascular endothelial growth factor plays a pivotal role in the progression of atherosclerotic lesions and causes instability of atherosclerotic plaques by inducing neoangiogenesis inside the current plaque. The pro-inflammatory cytokine interleukin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976cebacf9c5d49d49c93818516aec4a
https://doi.org/10.1097/01.fjc.0000191970.65998.7a
https://doi.org/10.1097/01.fjc.0000191970.65998.7a
Autor:
Christian Margeta, Chantel Spencer-Hänsch, Michael Leitges, Florian Blaschke, Giuseppe Biagini, Philipp Stawowy, Carsten Lindschau, Eckart Fleck, Kristof Graf
Publikováno v:
Cardiovascular Research. 67:50-59
Objective: Angiotensin II (AII) promotes cardiac fibrosis by increased extracellular matrix production and enhanced interaction of matrix proteins with their cellular receptors, including integrins. AII and other growth factors augment h1-integrin-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf8cbe7748b276b6c5a5b0db1db62356
https://doi.org/10.1016/j.cardiores.2005.03.002
https://doi.org/10.1016/j.cardiores.2005.03.002
Autor:
Kristof Graf, Nabil G. Seidah, Christian Margeta, Eckart Fleck, Adam Kilimnik, Philipp Stawowy, Heike Kallisch, Michel Chrétien
Publikováno v:
Biochemical and Biophysical Research Communications. 321:531-538
The IGF-1 receptor (IGF-1R) and MT1-MMP are synthesized as larger precursor proproteins, which require endoproteolytic activation by the proprotein convertases (PCs) furin/PC5 to gain full biological activity. The aim of this study was to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feda340d1ff8a8dd7a7910e5656167f7
https://doi.org/10.1016/j.bbrc.2004.07.001
https://doi.org/10.1016/j.bbrc.2004.07.001
Publikováno v:
Biochemical and Biophysical Research Communications. 303:74-80
Activation of MAPK pathways by angiotensin II (Ang II) is important for cardiac fibroblast (CFB) proliferation and migration. Activity of MAP-kinases is closely controlled by a group of dual-specific MAP kinase phosphatases (MKPs). Lipopolysaccharide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e53aac0c2227860bb05bfb00047273
https://doi.org/10.1016/s0006-291x(03)00301-2
https://doi.org/10.1016/s0006-291x(03)00301-2
Autor:
Maria Fritsch, Edith Schober, Michael E. Gschwandtner, Andrea Willfort-Ehringer, Oliver Schlager, Birgit Rami-Merhar, Renate Koppensteiner, Georgiana-Aura Giurgea, Sabine Steiner, Clemens Höbaus, Thomas Hörtenhuber, Gerit-Holger Schernthaner, Katrin Nagl, Christian Margeta
Publikováno v:
Wiener klinische Wochenschrift. 127(3-4)
Despite a marked improvement in the overall prognosis of patients with type 1 diabetes mellitus (T1DM), cardiovascular morbidity/mortality is still increased. Since cellular and microvascular aberrations have been demonstrated already in children wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2ad640475bcb2015b2178c7fffb453
https://pubmed.ncbi.nlm.nih.gov/25412591
https://pubmed.ncbi.nlm.nih.gov/25412591
Autor:
Alexandra Hammer, Georgiana-Aura Giurgea, Bernd Jilma, Renate Koppensteiner, Sophie Brunner-Ziegler, Christian Margeta, Raute Sunder-Plassmann, Martin Brunner, Dominic Magirr, Christine Mannhalter
Publikováno v:
British journal of haematology. 167(4)
Summary Interindividual variations in dose requirements of oral vitamin K antagonists (VKA) are attributed to several factors, including genetic variant alleles of vitamin K epoxide reductase complex subunit 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b490a55aa219aac2d94cad1baeabd1
https://pubmed.ncbi.nlm.nih.gov/25142093
https://pubmed.ncbi.nlm.nih.gov/25142093
Autor:
Alexandra Hammer, Renate Koppensteiner, Aura Giurgea, Markus Mueller, Michael E. Gschwandtner, Andrea Willfort-Ehringer, Christian Margeta, Teresa Ehringer, Silvia Charwat-Resl, Oliver Schlager, Sonja Zehetmayer
Publikováno v:
European journal of clinical investigation. 44(8)
Background Microcirculatory function can be assessed by postocclusive reactive hyperaemia (PORH) using laser Doppler fluxmetry. Previous studies have shown that PORH reveals microvascular damage at an early stage. In particular, at younger ages, PORH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148b484343edc08780f9e0a21c074228
https://pubmed.ncbi.nlm.nih.gov/24942279
https://pubmed.ncbi.nlm.nih.gov/24942279