Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christian Machacek"'
Autor:
Anna Ohradanova-Repic, Christian Machacek, Celine Charvet, Franck Lager, Delphine Le Roux, René Platzer, Vladimir Leksa, Goran Mitulovic, Thomas R. Burkard, Gerhard J. Zlabinger, Michael B. Fischer, Vincent Feuillet, Gilles Renault, Stephan Blüml, Miroslav Benko, Miloslav Suchanek, Johannes B. Huppa, Takami Matsuyama, Artur Cavaco-Paulo, Georges Bismuth, Hannes Stockinger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
If misregulated, macrophage (Mϕ)–T cell interactions can drive chronic inflammation thereby causing diseases, such as rheumatoid arthritis (RA). We report that in a proinflammatory environment, granulocyte-Mϕ (GM-CSF)- and Mϕ colony-stimulating
Externí odkaz:
https://doaj.org/article/e7777f70507942e1a7a5e9e49969aff6
Autor:
Franck Lager, Céline Charvet, Delphine Le Roux, Artur Cavaco-Paulo, Goran Mitulović, Johannes B. Huppa, Vladimir Leksa, Christian Machacek, Gilles Renault, Stephan Blüml, Vincent Feuillet, Gerhard J. Zlabinger, Thomas R Burkard, Anna Ohradanova-Repic, René Platzer, Takami Matsuyama, Hannes Stockinger, Michael B. Fischer, Georges Bismuth, Miloslav Suchánek, Miroslav Benko
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Immunology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
If misregulated, macrophage (M)T cell interactions can drive chronic inflammation thereby causing diseases, such as rheumatoid arthritis (RA). We report that in a proinflammatory environment, granulocyte-M (GM-CSF)- and M colony-stimulating factor (M
Autor:
Isabelle, Weinhofer, Bettina, Zierfuss, Simon, Hametner, Magdalena, Wagner, Niko, Popitsch, Christian, Machacek, Barbara, Bartolini, Gerhard, Zlabinger, Anna, Ohradanova-Repic, Hannes, Stockinger, Wolfgang, Köhler, Romana, Höftberger, Günther, Regelsberger, Sonja, Forss-Petter, Hans, Lassmann, Johannes, Berger
Publikováno v:
Brain
Weinhofer et al. reveal impaired plasticity of macrophages, with intrinsic pro-inflammatory skewing and a decreased ability to establish proper anti-inflammatory responses, in X-linked adrenoleukodystrophy (ALD). This may contribute to the rapidly pr
Publikováno v:
Science. 344:97-101
Backward or Forward Although land animals generally walk forward, they readily switch to walking backward if they sense an obstruction or danger in the path ahead. Such a switch is likely to involve a neural signal sent from the brain down to local m
Autor:
Christian Machacek, Armin Bahl, Michael S. Drews, Alexander Borst, Barry J. Dickson, Inês Ribeiro
Publikováno v:
Cell. 174:607-621.e18
Many animals rely on vision to detect, locate, and track moving objects. In Drosophila courtship, males primarily use visual cues to orient toward and follow females and to select the ipsilateral wing for courtship song. Here, we show that the LC10 v
Autor:
Vladimir Leksa, Hannes Stockinger, Karel Drbal, Andreas Spittler, Anna Ohradanova-Repic, Christian Machacek, Goran Mitulović, Miloslav Suchánek, Verena Supper
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(6)
Folate, also known as vitamin B9, is necessary for essential cellular functions such as DNA synthesis, repair, and methylation. It is supplied to the cell via several transporters and receptors, including folate receptor (FR) β, a GPI-anchored prote
Autor:
Alexandre M. Carmo, Catarina R. Almeida, Gonçalo J. L. Bernardes, Jaime Freitas, Alexandra Moreira, Ana Loureiro, Michael Burnet, Delphine Le Roux, Hannes Stockinger, Georges Bismuth, Anna Ohradanova-Repic, Céline Charvet, Christian Machacek, Patrícia Nogueira, Artur Cavaco-Paulo, Gilles Renault, Ana Preto, Franck Lager, Eugénia Nogueira, Andreia C. Gomes
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Methotrexate is the first line of treatment of rheumatoid arthritis. Since many patients become unresponsive to methotrexate treatment, only very expensive biological therapies are effective and increased methotrexate tolerance strategies need to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c68ab42dbaaa40e17ec8e6a4621957e
https://hdl.handle.net/1822/37777
https://hdl.handle.net/1822/37777
Autor:
Georg M. Guebitz, Tamara Reiter, Alexandra Rollett, Christian Machacek, Anna Ohradanova-Repic, Hannes Stockinger, Artur Cavaco-Paulo
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The chronic autoimmune disorder rheumatoid arthritis (RA) affects millions of adults and children every year. Chronically activated macrophages secreting enzymes and inflammatory cytokines play a key role in RA. Distinctive marker molecules on the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd02431dbeb8334a1d457c21e991afe9
Autor:
Evelyn Walenta, Barbara Thallinger, Anna Ohradanova-Repic, Hannes Stockinger, Christian Machacek, Alexandra Rollett, Georg M. Guebitz, Ruth Birner-Gruenberger, Juliane G. Bogner-Strauss, Artur Cavaco-Paulo
Publikováno v:
RSC Adv.
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Highly specific targeted drug delivery devices can be obtained with antibody-human serum albumin (mAb-HSA) conjugates. However, their conventional production involves several reaction steps including chemical modification and activation of both prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958261c179ddcc9247fe38c9e3ed3050
https://hdl.handle.net/1822/27462
https://hdl.handle.net/1822/27462
Autor:
Anna Ohradanova-Repic, Christian Machacek, Clemens Donner, Václav Hořejší, Eva Petrovčíková, Alexandra Zahradníková, Hannes Stockinger, Kristína Vičíková, Vanessa Mühlgrabner, Vladimir Leksa
Publikováno v:
Journal of Leukocyte Biology
The plasminogen system is harnessed in a wide variety of physiological processes, such as fibrinolysis, cell migration, or efferocytosis; and accordingly, it is essential upon inflammation, tissue remodeling, wound healing, and for homeostatic mainte