Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christian M Schambeck"'
Autor:
Karl Winkler, Vera Krane, Dialysis Study Investigators, Mario Berger, Christoph Wanner, Christian M. Schambeck, Jürgen Lilienthal
Publikováno v:
Clinical Journal of the American Society of Nephrology. 5:874-881
Background and objectives: Hemodialysis patients with type 2 diabetes exhibit an excessive cardiovascular risk and regularly receive heparin. We tested whether antibodies to the platelet factor 4–heparin complex (PF4-H-AB) contribute to outcome. De
Autor:
Florian Thieme, Christian M. Schambeck
Publikováno v:
Der Klinikarzt. 38:432-436
Molecular biological methods for thrombophilia screening have found their way into the coagulation laboratory since the middle of the eighties. Beside the frequent factor-V-Leiden-mutation and the prothrombin-G20210A-polymorphism a number of mutation
Autor:
Christian M. Schambeck
Publikováno v:
LaboratoriumsMedizin. 32:397-400
ZusammenfassungVon einer familiären Häufung von Lupusantikoagulanz und Anticardiolipin-Antikörper wurde immer wieder berichtet. Der Nachweis von Antiphospholipid-Antikörpern innerhalb einer Familie war nur gelegentlich mit klinischen Ereignissen
Autor:
Christian M Schambeck, Gerd Schmitz
Publikováno v:
Pathophysiology of Haemostasis and Thrombosis. 35:166-174
Platelet function is sensitive to alterations in cholesterol metabolism, and hypercholesterolemia is associated with enhanced platelet reagibility. Atherogenic low-density lipoproteins (LDL), in particular oxidized LDL, activate src-kinase-family-dep
Autor:
Christian M. Schambeck
Publikováno v:
LaboratoriumsMedizin. 28:453-462
Autor:
Kathleen Teuchert, Alois Spahn, Mario Berger, Christian M. Schambeck, Ralf Grossmann, Ulrich Walter, Sarah Zonnur
Publikováno v:
Thrombosis and Haemostasis. 92:42-46
SummaryTheoretically, von Willebrand factor (VWF) should be capable of binding all factor VIII (FVIII), but an unbound FVIII (uFVIII) plasma fraction remains. In patients’ status post deep-vein thrombosis (DVT), an altered uFVIII fraction and high
Autor:
Franz Keller, B. Mansouri Taleghani, Christian M. Schambeck, D. Wahler, I. Haubitz, K. Hinney
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 21:289-292
Abstract —High levels of factor VIII (FVIII) but not von Willebrand factor (vWF) are known to increase the risk for venous thromboembolism. Whether high FVIII levels originate from hereditary defects or from acquired conditions remains unanswered.
Autor:
Christian M. Schambeck, Petra Zeitler, Francoise Meire, Stefan Seregard, Anne-Marie Mingers, Hans Wolfgang Kreth, Ugur Ozcelik, Deniz Anadol, Volker Schuster, Lori Luchtman-Jones
Publikováno v:
Scopus-Elsevier
SummarySevere type I plasminogen deficiency has been recently linked to ligneous conjunctivitis, a rare and uncommon form of chronic conjunctivitis. In this study, eight unrelated ligneous conjunctivitis patients living in different parts of the worl
Publikováno v:
Thrombosis and Haemostasis. 85:782-786
SummaryHypercoagulability is observed in patients with inherited thrombophilia, e.g. factor V Leiden (FVL) mutation. Pregnancy represents a hypercoagulable state as well. This study addresses the effects of the FVL mutation on haemostatic activation
Publikováno v:
Thrombosis and Haemostasis. 78:1480-1483
SummaryThe cumulative thrombotic risk of Factor V (FV) Leiden and oral contraceptives (OC) recommends screening for the mutation. Assuming that a family history of thrombosis increases the patient’s likelihood of bearing FV Leiden, a selective rath