Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Christian Lupinek"'
Autor:
Gabrielle Pauli, Carole Wurmser, Antoine Roos, Cosme Kokou, Huey-Jy Huang, Nishelle D’souza, Christian Lupinek, Josefina Zakzuk, Ronald Regino, Nathalie Acevedo, Luis Caraballo, Susanne Vrtala, Rudolf Valenta
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundAsthma is not well investigated in equatorial Africa and little is known about the disease-associated allergen molecules recognized by IgE from patients in this area. The aim was to study the molecular IgE sensitization profile of asthmatic
Externí odkaz:
https://doaj.org/article/72757fef65484a6ca8616474c4753d51
Autor:
Ines Zettl, Tatiana Ivanova, Mohammed Zghaebi, Marina V. Rutovskaya, Isabella Ellinger, Oksana Goryainova, Jessica Kollárová, Sergio Villazala-Merino, Christian Lupinek, Christina Weichwald, Anja Drescher, Julia Eckl-Dorna, Sergei V. Tillib, Sabine Flicker
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The nasal cavity is an important site of allergen entry. Hence, it represents an organ where trans-epithelial allergen penetration and subsequent IgE-mediated allergic inflammation can potentially be inhibited. Intercellular adhesion molecule 1 (ICAM
Externí odkaz:
https://doaj.org/article/921e0cd4744a44a5a366ba6a25eee897
Autor:
Pia Gattinger, Irene Mittermann, Christian Lupinek, Gerhard Hofer, Walter Keller, Urska Bidovec Stojkovic, Peter Korosec, Christine Koessler, Natalija Novak, Rudolf Valenta
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 33-43 (2019)
Background: N-linked glycans present in venoms, pollen and mites are recognized by IgE antibodies from >20% of allergic patients but have low or no allergenic activity. Objectives: To engineer recombinant glycoproteins resembling carbohydrate-specifi
Externí odkaz:
https://doaj.org/article/5b9323df3a8745fbac3a719213f87cc2
Autor:
Gabrielle Pauli, Carole Wurmser-Danion, Antoine Roos, Cosme Kokou, Huey-Jy Huang, Christian Lupinek, Josefina Zakzuk, Caraballo Luis, Vrtala Susanne, Valenta Rudolf
Publikováno v:
World Allergy Organization Journal, Vol 13, Iss 8, Pp 100160- (2020)
Externí odkaz:
https://doaj.org/article/99c549d23d5942fba0078b3ae373e0f4
Autor:
Katarzyna Niespodziana, Katarina Stenberg-Hammar, Spyridon Megremis, Clarissa R. Cabauatan, Kamila Napora-Wijata, Phyllis C. Vacal, Daniela Gallerano, Christian Lupinek, Daniel Ebner, Thomas Schlederer, Christian Harwanegg, Cilla Söderhäll, Marianne van Hage, Gunilla Hedlin, Nikolaos G. Papadopoulos, Rudolf Valenta
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Rhinovirus (RV) infections can trigger acute exacerbations of respiratory diseases. Here, Niespodziana et al. develop a PreDicta chip that identifies the culprit RV strain from small blood samples and show that RV-A and RV-C strains are associated wi
Externí odkaz:
https://doaj.org/article/f0e5b1e0483a415e8d8be627de283b8b
Autor:
Magnus Wickman, Christian Lupinek, Niklas Andersson, Danielle Belgrave, Anna Asarnoj, Marta Benet, Mariona Pinart, Sandra Wieser, Judith Garcia-Aymerich, Alexandra Baar, Göran Pershagen, Angela Simpson, Inger Kull, Anna Bergström, Erik Melén, Carl Hamsten, Josep M. Antó, Jean Bousquet, Adnan Custovic, Rudolf Valenta, Marianne van Hage
Publikováno v:
EBioMedicine, Vol 26, Iss C, Pp 91-99 (2017)
Background: Sensitization in early childhood may precede respiratory allergy in adolescence. Methods: IgE reactivity against 132 allergen molecules was evaluated using the MeDALL microarray in sera obtained from a random sample of 786 children at the
Externí odkaz:
https://doaj.org/article/ff9e584d52aa45b1a9305dc48a54ba7a
Autor:
Christian Lupinek, Kurt Derfler, Silvia Lee, Thomas Prikoszovich, Oliver Movadat, Eva Wollmann, Carolin Cornelius, Milena Weber, Renate Fröschl, Regina Selb, Katharina Blatt, Dubravka Smiljkovic, Volker Schoder, René Cervenka, Thomas Plaichner, Gottfried Stegfellner, Hans Huber, Rainer Henning, Justyna Kozik-Jaromin, Thomas Perkmann, Verena Niederberger, Ventzislav Petkov, Peter Valent, Adelheid Gauly, Hans Peter Leinenbach, Ingrid Uhlenbusch-Koerwer, Rudolf Valenta
Publikováno v:
EBioMedicine, Vol 17, Iss C, Pp 119-133 (2017)
Background: Prevention of IgE-binding to cellular IgE-receptors by anti-IgE (Omalizumab) is clinically effective in allergic asthma, but limited by IgE threshold-levels. To overcome this limitation, we developed a single-use IgE immunoadsorber column
Externí odkaz:
https://doaj.org/article/fc182c7678904540a33c121811dc1d3f
Autor:
Pia Gattinger, Christian Lupinek, Lampros Kalogiros, Mira Silar, Mihaela Zidarn, Peter Korosec, Christine Koessler, Natalija Novak, Rudolf Valenta, Irene Mittermann
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199250 (2018)
BackgroundAllergy to bee and wasp venom can lead to life-threatening systemic reactions. The identification of the culprit species is important for allergen-specific immunotherapy.ObjectivesTo determine a panel of recombinant bee and wasp allergens w
Externí odkaz:
https://doaj.org/article/efbd51ea219148d4bade3c1f4223118c
IgE Sensitization Profiles Differ between Adult Patients with Severe and Moderate Atopic Dermatitis.
Autor:
Irene Mittermann, Gustav Wikberg, Catharina Johansson, Christian Lupinek, Lena Lundeberg, Reto Crameri, Rudolf Valenta, Annika Scheynius
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156077 (2016)
BackgroundAtopic dermatitis (AD) is a complex chronic inflammatory disease where allergens can act as specific triggering factors.AimTo characterize the specificities of IgE-reactivity in patients with AD to a broad panel of exogenous allergens inclu
Externí odkaz:
https://doaj.org/article/42f3c48395e74fdda3605512348e6cdc
Autor:
Yvonne Resch, Katharina Blatt, Ursula Malkus, Christian Fercher, Ines Swoboda, Margit Focke-Tejkl, Kuan-Wei Chen, Susanne Seiberler, Irene Mittermann, Christian Lupinek, Azahara Rodriguez-Dominguez, Petra Zieglmayer, René Zieglmayer, Walter Keller, Vladislav Krzyzanek, Peter Valent, Rudolf Valenta, Susanne Vrtala
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160641 (2016)
BACKGROUND:The house dust mite (HDM) allergen Der p 18 belongs to the glycoside hydrolase family 18 chitinases. The relevance of Der p 18 for house dust mite allergic patients has only been partly investigated. OBJECTIVE:To perform a detailed charact
Externí odkaz:
https://doaj.org/article/461a488a873d4b949bd136a203c70cca