Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Christian Lohr"'
Autor:
Marina Wendlandt, Alina J. Kürten, Antonia Beiersdorfer, Charlotte Schubert, Kiana Samad-Yazdtchi, Jessica Sauer, M. Carolina Pinto, Kristina Schulz, Manuel A. Friese, Christine E. Gee, Daniela Hirnet, Christian Lohr
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe cyclic nucleotide cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger, which is known to play an important anti-inflammatory role. Astrocytes in the central nervous system (CNS) can modulate inflammation but little
Externí odkaz:
https://doaj.org/article/4efe47dd39af48f7be496c62d1ac970c
Autor:
Brenna C. Fearey, Lars Binkle, Daniel Mensching, Christian Schulze, Christian Lohr, Manuel A. Friese, Thomas G. Oertner, Christine E. Gee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The transient receptor potential melastatin 4 (TRPM4) channel contributes to disease severity in the murine experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis and to neuronal cell death in models of excitotoxicity an
Externí odkaz:
https://doaj.org/article/3bd731c3c1254a9889512194675bf219
Autor:
Florian L. Schwarzenberg, Paul Schütz, Jörg U. Hammel, Mirko Riedel, Jasmin Bartl, Sharareh Bordbari, Svea-Celina Frank, Bernd Walkenfort, Madleen Busse, Julia Herzen, Christian Lohr, Clemens Wülfing, Stephan Henne
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
With growing molecular evidence for correlations between spatial arrangement of blood vasculature and fundamental immunological functions, carried out in distinct compartments of the subdivided lymph node, there is an urgent need for three-dimensiona
Externí odkaz:
https://doaj.org/article/40aa944221fe4139bfcaa1ea66678891
Autor:
Hauke Simon Günther, Stephan Henne, Jasmin Oehlmann, Julia Urban, Desiree Pleizier, Nicklas Renevier, Christian Lohr, Clemens Wülfing
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Recently, we found many immune cells including antigen presenting cells neurally hard wired in the T-cell zone of most lymphoid organs like amongst others, lymph nodes in rats, mice and humans. Single immune cells were reached by single neur
Externí odkaz:
https://doaj.org/article/a8fce741d001411bbc432ddcdc364c44
Autor:
Jakob Matschke, Henri Lahann, Susanne Krasemann, Hermann Altmeppen, Susanne Pfefferle, Giovanna Galliciotti, Antonia Fitzek, Jan-Peter Sperhake, Benjamin Ondruschka, Miriam Busch, Natalie Rotermund, Kristina Schulz, Christian Lohr, Matthias Dottermusch, Markus Glatzel
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
The severe acute respiratory syndrome-corona virus type 2 (SARS-CoV-2) is the cause of human coronavirus disease 2019 (COVID-19). Since its identification in late 2019 SARS-CoV-2 has spread rapidly around the world creating a global pandemic. Althoug
Externí odkaz:
https://doaj.org/article/89c079962cd4429fa4a2e80231ddf2a9
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/ecfacf58522f4b3fba1ec307fc577ffa
Autor:
Christian Lohr, Antonia Beiersdorfer, Timo Fischer, Daniela Hirnet, Natalie Rotermund, Jessica Sauer, Kristina Schulz, Christine E. Gee
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Ca2+ imaging is the most frequently used technique to study glial cell physiology. While chemical Ca2+ indicators served to visualize and measure changes in glial cell cytosolic Ca2+ concentration for several decades, genetically encoded Ca2+ indicat
Externí odkaz:
https://doaj.org/article/68c930d6ca174b7388de6584b00af867
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
It is well-established that astrocytes respond to norepinephrine with cytosolic calcium rises in various brain areas, such as hippocampus or neocortex. However, less is known about the effect of norepinephrine on olfactory bulb astrocytes. In the pre
Externí odkaz:
https://doaj.org/article/ddd13eea4a6644ffaf0969b7b87acb30
Autor:
André T Lopes, Torben J Hausrat, Frank F Heisler, Kira V Gromova, Franco L Lombino, Timo Fischer, Laura Ruschkies, Petra Breiden, Edda Thies, Irm Hermans-Borgmeyer, Michaela Schweizer, Jürgen R Schwarz, Christian Lohr, Matthias Kneussel
Publikováno v:
PLoS Biology, Vol 18, Iss 8, p e3000820 (2020)
Mutations in the gene encoding the microtubule-severing protein spastin (spastic paraplegia 4 [SPG4]) cause hereditary spastic paraplegia (HSP), associated with neurodegeneration, spasticity, and motor impairment. Complicated forms (complicated HSP [
Externí odkaz:
https://doaj.org/article/fd94a10cc9314b0d9d95e7c1e309a73e
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Astrocytes have a high impact on the structure of the central nervous system, as they control neural activity, development, and plasticity. Heterogeneity of astrocytes has been shown before, but so far only a few studies have demonstrated heterogeneo
Externí odkaz:
https://doaj.org/article/169b962bafd04dd09a1fffaed9a0aa5c