Efficacy and safety of SQ house dust mite (HDM) SLIT-tablet treatment of HDM allergic asthma

Autor: Johann Christian Virchow, Giorgio Walter Canonica, Ida Mosbech Smith, Christian Ljørring, Holger Mosbech, P. Zieglmayer

Publikováno v: Expert Review of Clinical Immunology. 12:805-815

In the treatment of house dust mite (HDM) respiratory allergic disease, allergy immunotherapy constitutes an add-on treatment option targeting the underlying immunological mechanisms of allergic disease. However, for the treatment of HDM allergic ast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7cfa22f5c5bedd4429befbd9114c33e
https://doi.org/10.1080/1744666x.2016.1200467

UK Immunotherapy Study: Reanalysis by a combined symptom and medication score

Autor: Eike Wüstenberg, Stephen R. Durham, Oliver Pfaar, Christian Ljørring, Richard J. Powell, Anthony J. Frew, Hendrik Wolf, Christopher Corrigan

Publikováno v: 1999.e3
Frew, A J, Ljørring, C, Wolf, H, Wüstenberg, E, Durham, S R, Corrigan, C J, Powell, R J & Pfaar, O 2018, ' UK Immunotherapy Study : Reanalysis by a combined symptom and medication score ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2018.07.034

Reanalysis of UK22 subcutaneous immunotherapy trial according to WAO/EAACI recommendations revealed clinically relevant improvements at both doses. Starting at the lower dose should enable efficacy with lower risk of adverse events.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171acbcbf400bb4199522d34caa26f02
https://pubmed.ncbi.nlm.nih.gov/30149039

Asthma symptoms, SABA use, and lung function before and after a moderate or severe exacerbation

Autor: Ida Mosbech Smith, Dorte Rehm, Hanne H. Villesen, Johann Christian Virchow, Christian Ljørring, Victoria Cardona

Publikováno v: Allergy and immunology.

For allergic asthma patients, exacerbations represent a medical need and source of anxiety. To explore how exacerbations affect patients, we present descriptive data from a phase III trial in adults with house dust mite (HDM) allergic asthma not well

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ddb9fd5d412069605d7553812477b7e
https://doi.org/10.1183/1393003.congress-2017.pa4051

Efficacy of a House Dust Mite Sublingual Allergen Immunotherapy Tablet in Adults With Allergic Asthma: A Randomized Clinical Trial

Autor: Frédéric de Blay, Luis Prieto, Hendrik Nolte, Hanne H. Villesen, Piotr Kuna, J. Christian Virchow, Bente Juel Riis, Vibeke Backer, Christian Ljørring

Publikováno v: JAMA. 315(16)

Importance The house dust mite (HDM) sublingual allergen immunotherapy (SLIT) tablet is a potential novel treatment option for HDM allergy–related asthma. Objectives To evaluate the efficacy and adverse events of the HDM SLIT tablet vs placebo for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb594714d828b3f095a13823cef9025
https://pubmed.ncbi.nlm.nih.gov/27121851

Predictive biomarkers of clinical efficacy of allergen-specific immunotherapy: how to proceed

Autor: Peter Adler Würtzen, Christian Ljørring, Mohamed H. Shamji

Publikováno v: Immunotherapy. 5(3)

Various mode-of-action studies have been conducted to describe and substantiate the immuno logic mechanisms behind the long-lasting effect of allergen-specific immunotherapy (SIT) and how it changes the course of IgEmediated allergic disease. These r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a071880eed03f0be47a5ef8e109455f
https://pubmed.ncbi.nlm.nih.gov/23444948