Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Christian Lherbet"'
Autor:
Pascal Hoffmann, Joëlle Azéma-Despeyroux, Fernanda Goncalves, Alessandro Stamilla, Nathalie Saffon-Merceron, Frédéric Rodriguez, Giulia Degiacomi, Maria Rosalia Pasca, Christian Lherbet
Publikováno v:
Molecules, Vol 29, Iss 13, p 3076 (2024)
Tuberculosis is a serious public health problem worldwide. The search for new antibiotics has become a priority, especially with the emergence of resistant strains. A new family of imidazoquinoline derivatives, structurally analogous to triazolophtha
Externí odkaz:
https://doaj.org/article/2c1ad0e2eed648a4ab889c946f63fcb2
Autor:
Ebru Koçak Aslan, Muhammed İhsan Han, Vagolu Siva Krishna, Rasoul Tamhaev, Cagatay Dengiz, Şengül Dilem Doğan, Christian Lherbet, Lionel Mourey, Tone Tønjum, Miyase Gözde Gündüz
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1301 (2022)
Isoniazid (INH) is one of the key molecules employed in the treatment of tuberculosis (TB), the most deadly infectious disease worldwide. However, the efficacy of this cornerstone drug has seriously decreased due to emerging INH-resistant strains of
Externí odkaz:
https://doaj.org/article/a33981310c2b4397b04312c17265e4aa
Publikováno v:
Molecules, Vol 24, Iss 14, p 2567 (2019)
Cannabigerol (CBG) and cannabichromene (CBC) are non-psychoactive cannabinoids that have raised increasing interest in recent years. These compounds exhibit good tolerability and low toxicity, representing promising candidates for drug repositioning.
Externí odkaz:
https://doaj.org/article/e4f0d7180db243c08cd1f7122e81f90e
Autor:
Paulo F. M. Oliveira, Brigitte Guidetti, Alain Chamayou, Christiane André-Barrès, Jan Madacki, Jana Korduláková, Giorgia Mori, Beatrice Silvia Orena, Laurent Roberto Chiarelli, Maria Rosalia Pasca, Christian Lherbet, Chantal Carayon, Stéphane Massou, Michel Baron, Michel Baltas
Publikováno v:
Molecules, Vol 22, Iss 9, p 1457 (2017)
A series of isoniazid derivatives bearing a phenolic or heteroaromatic coupled frame were obtained by mechanochemical means. Their pH stability and their structural (conformer/isomer) analysis were checked. The activity of prepared derivatives agains
Externí odkaz:
https://doaj.org/article/9f6c08ce7bc345f7b29d36e415a22d7c
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 6, Pp o963-o963 (2013)
In the title compound, C23H18FNO3, the tricyclic 9-fluorenyl system is approximately planar (r.m.s. deviation = 0.0279 Å). The N—C(=O) bond length is comparatively short [1.359 (3) Å], which is typical for such conjugated systems. The N atom has
Externí odkaz:
https://doaj.org/article/f78ebbe2697e46d6a1ac450652d43d8d
Autor:
Michael Tapera, Hüseyin Kekeçmuhammed, Kader Sahin, Vagolu Siva Krishna, Christian Lherbet, Håvard Homberset, Mélina Chebaiki, Tone Tønjum, Lionel Mourey, Yunus Zorlu, Serdar Durdagi, Emin Sarıpınar
Publikováno v:
Journal of Molecular Structure
Journal of Molecular Structure, 2022, 1270, pp.133899. ⟨10.1016/j.molstruc.2022.133899⟩
Journal of Molecular Structure, 2022, 1270, pp.133899. ⟨10.1016/j.molstruc.2022.133899⟩
The emergence of drug-resistant Mycobacterium tuberculosis strains has posed a driving demand in the search for more effective treatment regimens for tuberculosis. In the present study, a series of novel thiourea derivatives containing aminoguanidine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aedcc6518474679d70e4115166f8f0b
https://hal.science/hal-03797382/file/JmolStruct_Lherbet.pdf
https://hal.science/hal-03797382/file/JmolStruct_Lherbet.pdf
Autor:
Pascal Hoffmann, Christian Lherbet, Isabelle Fabing, Marie-Claire Barthélémy, Yann Borjon-Piron, Christophe Laurent, Alain Vigroux
Publikováno v:
RSC Advances
RSC Advances, 2022, 12 (41), pp.26825-26833. ⟨10.1039/d2ra04298c⟩
RSC Advances, 2022, 12 (41), pp.26825-26833. ⟨10.1039/d2ra04298c⟩
Cr-MIL-101-NH2 (MOF1) has been used to encapsulate large amounts of copper sulfate and the resulting loaded material, Cu@MOF1, was successfully used to promote the CuAAC click reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e228da902258f0e8fc80d86ee7dd9a
https://hal.science/hal-03785805
https://hal.science/hal-03785805
Autor:
Rüveyde Keleş Atıcı, Şengül Dilem Doğan, Miyase Gözde Gündüz, Vagolu Siva Krishna, Melina Chebaiki, Håvard Homberset, Christian Lherbet, Lionel Mourey, Tone Tønjum
Publikováno v:
Drug Development Research
Drug Development Research, 2022, 83 (6), pp.1292-1304. ⟨10.1002/ddr.21958⟩
Drug Development Research, 2022, 83 (6), pp.1292-1304. ⟨10.1002/ddr.21958⟩
© 2022 Wiley Periodicals LLC.The recent emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb) has complicated and significantly slowed efforts to eradicate and/or reduce the worldwide incidence of life-threatening acute and chronic
Autor:
S.R. Prem Kumar, Ibrahim Ahmed Shaikh, Mater H. Mahnashi, Mohammed Abdulrahman Alshahrani, Sheshagiri R. Dixit, Venkatarao H. Kulkarni, Christian Lherbet, Andanappa K. Gadad, Tejraj M. Aminabhavi, Shrinivas D. Joshi
Publikováno v:
Journal of the Indian Chemical Society. 99:100674
Autor:
V. H. Kulkarni, Christian Lherbet, Shrinivas D. Joshi, Jeelan Basha, Mallikarjuna N. Nadagouda, Tejraj M. Aminabhavi, Sheshagiri R. Dixit
Publikováno v:
Bioorganic Chemistry
Bioorganic Chemistry, Elsevier, 2018, 81, pp.440-453. ⟨10.1016/j.bioorg.2018.08.035⟩
Bioorganic Chemistry, Elsevier, 2018, 81, pp.440-453. ⟨10.1016/j.bioorg.2018.08.035⟩
In an effort to produce new lead antimycobacterial compounds, herein we have reported the synthesis of a sequence of new pyrrolyl benzamide derivatives. The new chemical entities were screened to target enoyl-ACP reductase enzyme, which is one of the