Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Christian Legind"'
Autor:
Mette Ødegaard Nielsen, Egill Rostrup, Rikke Hilker, Christian Legind, Simon Anhøj, Trevor William Robbins, Barbara J. Sahakian, Birgitte Fagerlund, Birte Glenthøj
Publikováno v:
Biological Psychiatry Global Open Science, Vol 3, Iss 1, Pp 47-55 (2023)
Background: Findings of reward disturbances in unaffected relatives of patients with schizophrenia suggest reward disturbances as an endophenotype for schizophrenia. Twin studies, where 1 twin has been diagnosed with a schizophrenia spectrum disorder
Externí odkaz:
https://doaj.org/article/71af95785caf4365a5beae1b75940fea
Publikováno v:
European Psychiatry, Vol 66 (2023)
In Denmark, a 10-year plan for psychiatry has been agreed on. The content of the plan was developed in collaboration between the Danish Health Authority and the Danish Authority for Social Services and Housing, and it involved many stakeholders. Rece
Externí odkaz:
https://doaj.org/article/f50e9cfb287a47f1863980889494f900
Autor:
Barbara J. Sahakian, Birgitte Fagerlund, Rachel M. Brouwer, Cecilie K Lemvigh, Trevor W. Robbins, Rikke Hilker, Christos Pantelis, Maria Høj Jensen, Simon Anhøj, Christian Legind, Birte Glenthøj
Publikováno v:
Psychological Medicine. 52:1101-1114
BackgroundMany cognitive functions are under strong genetic control and twin studies have demonstrated genetic overlap between some aspects of cognition and schizophrenia. How the genetic relationship between specific cognitive functions and schizoph
Autor:
Simon Anhøj, Rikke Hilker, Christian Legind, Rachel M. Brouwer, Maria H. Jensen, Birgitte Fagerlund, René C.W. Mandl, Hilleke E. Hulshoff Pol, Brian V. Broberg, Bjørn H Ebdrup, Birte Glenthøj, Egill Rostrup
Publikováno v:
Schizophr Bull
Whether aberrant cerebral blood flow (CBF) in schizophrenia is affected by genetic influences, and consequently a potential marker for genetic susceptibility, is unknown. Our aims were to determine the heritability of CBF in thalamic, frontal, and st
Autor:
Trevor W. Robbins, Birgitte Fagerlund, Louise Baruël Johansen, Barbara J. Sahakian, Christian Legind, Hilleke E. Hulshoff Pol, Cecilie K Lemvigh, Rachel M. Brouwer, Bjørn H Ebdrup, Birte Glenthøj, Simon Anhøj, Christos Pantelis, Rikke Hilker
Publikováno v:
Lemvigh, C, Brouwer, R M, Sahakian, B J, Robbins, T W, Johansen, L, Legind, C, Anhøj, S, Hilker, R W, Hulshoff Pol, H E, Ebdrup, B, Pantelis, C, Glenthøj, B Y & Fagerlund, B 2020, ' Heritability of Memory Functions and Related Brain Volumes: A Schizophrenia Spectrum Study of 214 Twins ', Schizophrenia Bulletin Open, vol. 1, no. 1, sgaa066 . https://doi.org/10.1093/schizbullopen/sgaa066
BackgroundMemory performance is heritable and shares partial genetic etiology with schizophrenia. How the genetic overlap between memory and schizophrenia is related to intelligence (IQ) and brain volumes has not been formally tested using twin model
Autor:
Birgitte Fagerlund, Birte Glenthøj, Christian Legind, Brian V. Broberg, Egill Rostrup, Bjørn H Ebdrup, Rachel M. Brouwer, Rikke Hilker, Hilleke E. Hulshoff Pol, Maria H. Jensen, Simon Anhøj, René C.W. Mandl
BACKGROUND: Regional cerebral blood flow (rCBF) has been found altered in the thalamus, frontal regions and the putamen of patients with schizophrenia. It is not known if these changes in rCBF are due to genetic influences, but findings of altered rC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67fd26a02b915b58d10ebc2ec93dc0c
https://europepmc.org/articles/PMC6455543/
https://europepmc.org/articles/PMC6455543/
Autor:
Brian V. Broberg, Simon Anhøj, Rikke Hilker, Rachel M. Brouwer, Egill Rostrup, Maria Høj Jensen, Christian Legind, Hilleke E. Hulshoff Pol, Birte Glenthøj, René Christiaan William Mandl, Philip McGuire, Birgitte Fagerlund
Publikováno v:
Neuropsychopharmacology, 44(3), 581. Nature Publishing Group
Research findings implicate cerebral glutamate in the pathophysiology of schizophrenia, including genetic studies reporting associations with glutamatergic neurotransmission. The extent to which aberrant glutamate levels can be explained by genetic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf323340570d899130995f07709a26b
https://dspace.library.uu.nl/handle/1874/387906
https://dspace.library.uu.nl/handle/1874/387906
Autor:
Christian Legind, Maria Høj Jensen, Birte Glenthøj, Rikke Hilker, Birgitte Fagerlund, Merete Nordentoft, Mette Olaf Nielsen, Brian V. Broberg, Simon Anhøj
Publikováno v:
Schizophrenia Bulletin
Background Studies have shown that the risk of developing schizophrenia is associated with an increased risk of most other psychiatric disorders1 and that the familial transmission of risk extends across diagnostic categories.2 In twin studies, unaff
Autor:
Christian Legind, Birte Glenthøj, Mette Olaf Nielsen, Rikke Hilker, Helle Schaebel, Gitte Saltoft Andersen
Publikováno v:
Schizophrenia Bulletin. 45:S301-S301
BACKGROUND: Patients with schizophrenia often report impaired quality of life. Being a first-degree relative to patients with schizophrenia may also affect the quality of life. In addition to being concerned for the affected sibling, there may be an
Autor:
Rikke Hilker, Maria Høj Jensen, Hilleke E. Hulshoff Pol, Birte Glenthøj, Brian V. Broberg, Birgitte Fagerlund, Christian Legind, Egill Rostrup, Simon Anhøj, Rachel M. Brouwer, Philip McGuire, René C.W. Mandl
Publikováno v:
Schizophrenia Bulletin
Background Glutamatergic changes in schizophrenia may precede dopaminergic alterations leading to psychopathology as part of a dopaminergic pathway, or they may represent a distinct pathophysiology. It is unknown if these glutamatergic alterations ar