Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Christian Lattermann"'
Autor:
Tiago Lazzaretti Fernandes, Joao P.C. SantAnna, Mario Sergio Boff, Caio Gomes Tabet, Betina B. Hinckel, Seth L. Sherman, Christian Lattermann
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 4, Iss 2, Pp 100172- (2024)
Introduction: Cartilage lesions and osteoarthritis are very prevalent and imply a significant clinical and economic burden. Objectives: To review treatments for cartilage lesions in a time life sequence and its particularities. Methods: We performed
Externí odkaz:
https://doaj.org/article/5785e03ca3d64db9a7f54b57a72688df
Autor:
Mark S. Fineman, Timothy E. McAlindon, Christian Lattermann, Christopher J. Swearingen, Sarah Kennedy, Victor A. Lopez, Ismail Simsek, Jeyanesh R. S. Tambiah, Yusuf Yazici
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 6, Pp 1741-1752 (2023)
Abstract Introduction Knee osteoarthritis (OA) is a common painful disorder. Intra-articular (IA) corticosteroid injections are frequently prescribed to treat knee pain. Lorecivivint (LOR), a novel IA cdc2-Like Kinase (CLK)/Dual-Specificity Tyrosine
Externí odkaz:
https://doaj.org/article/69c83b43b37a484fb4ee0ec029fd4f79
Autor:
Laura E. Keller, Lisa A. Fortier, Christian Lattermann, Emily R. Hunt, Sheng Zhang, Qin Fu, Cale A. Jacobs
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 3, Iss 4, Pp 100114- (2023)
Introduction: Patients with anterior cruciate ligament injury are at high risk of posttraumatic osteoarthritis and their response to reconstructive surgery and rehabilitation vary. Proteins identified in the orchestration of the acute inflammatory re
Externí odkaz:
https://doaj.org/article/6406a415710344f9963bc499a775216f
Orthobiologics in orthopedic applications: a report from the TMI Havemeyer meeting on orthobiologics
Autor:
Christian Lattermann, Chilan B.G. Leite, David D. Frisbie, Theodore S. Schlegel, Larry R. Bramlage, Thomas Koch, Christopher Centeno, Laurie R. Goodrich, Brian Johnstone, Rocci Trumper, Ashlee Watts, Christopher Little, Frank Barry, Farsh Guilak, C. Wayne McIlwraith
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 2, Iss 3, Pp 100055- (2022)
Readily available and effective therapeutic approaches are increasingly required to overcome the growing demand for optimized management of musculoskeletal degenerative conditions. The use of biologic therapies has been gaining ground in the orthoped
Externí odkaz:
https://doaj.org/article/a8f85c5b8fcd4d33be0f8938b705ef55
Autor:
Eli T. Sayegh, Molly Zgoda, Chilan B.G. Leite, Andrea C. Carrano, Jeyanesh Tambiah, Christian Lattermann
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 2, Iss 3, Pp 100069- (2022)
Background: Osteoarthritis (OA) is a chronic, degenerative condition associated with joint pain and disability. Because Wnt pathway signaling activity is abnormally upregulated in preclinical OA models, its inhibition is a target for disease-modifyin
Externí odkaz:
https://doaj.org/article/2f087954f8ff4d3aadf6c1aceb9b28fb
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 1, Iss 3, Pp 100024- (2021)
With novel and minimally invasive therapies increasingly sought after to address acute and chronic conditions of the musculoskeletal system, orthoregenerative strategies have been gaining attention given their potential to modulate and improve the bo
Externí odkaz:
https://doaj.org/article/c559f57736d64661ae6c6b1ac5b4a19e
Autor:
Gergo Merkely, M.D., Alireza Borjali, Ph.D., Molly Zgoda, Evan M. Farina, M.D., Simon Görtz, M.D., Orhun Muratoglu, Ph.D., Christian Lattermann, M.D., Kartik M. Varadarajan, Ph.D.
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 1, Iss 2, Pp 100009- (2021)
Introduction: MRI is the modality of choice for cartilage imaging, however, its diagnostic performance is variable. Objectives: We aimed to evaluate whether deep learning can be utilized to accurately identify cartilage defects when applied to the in
Externí odkaz:
https://doaj.org/article/fef03e33000e42609d19989a14cecaf3
Autor:
Cale A. Jacobs, Ryan A. Mace, Jonathan Greenberg, Paula J. Popok, Mira Reichman, Christian Lattermann, Jessica L. Burris, Eric A. Macklin, Ana-Maria Vranceanu
Publikováno v:
Contemporary Clinical Trials Communications, Vol 21, Iss , Pp 100720- (2021)
Knee osteoarthritis (OA) is the most common joint disorder in the U.S. and a leading cause of disability. Depression and obesity are highly comorbid among knee OA patients, and the combination of obesity and depression is associated with decreased ph
Externí odkaz:
https://doaj.org/article/a59d10b37a8d4bf8a927491e91ad1d4c
Autor:
Tiago Lazzaretti Fernandes, Andreas H. Gomoll, Christian Lattermann, Arnaldo Jose Hernandez, Daniela Franco Bueno, Mariane Tami Amano
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cartilage lesions and osteoarthritis (OA) presents an ever-increasing clinical and socioeconomic burden. Synovial inflammation and articular inflammatory environment are the key factor for chondrocytes apoptosis and hypertrophy, ectopic bone formatio
Externí odkaz:
https://doaj.org/article/12307f92fe034ddb846658b7fa816a4d
Autor:
Kate Kosmac, Bailey Peck, R. Walton, Jyothi Mula, Philip Kern, Marcas Bamman, Richard Dennis, Cale Jacobs, Christian Lattermann, Darren Johnson, Charlotte Peterson
Publikováno v:
Bio-Protocol, Vol 8, Iss 12 (2018)
Macrophages have well-characterized roles in skeletal muscle repair and regeneration. Relatively little is known regarding the role of resident macrophages in skeletal muscle homeostasis, extracellular matrix remodeling, growth, metabolism and adapta
Externí odkaz:
https://doaj.org/article/1c03783fd930446a9611b1137b759749