Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Christian Lanciault"'
Autor:
Emerson Y. Chen, Adel Kardosh, Nima Nabavizadeh, Bryan Foster, Skye C. Mayo, Kevin G. Billingsley, Erin W. Gilbert, Christian Lanciault, Aaron Grossberg, Kenneth G. Bensch, Erin Maynard, Eric C. Anderson, Brett C. Sheppard, Charles R. Thomas Jr, Charles D. Lopez, Gina M. Vaccaro, OHSU Gastrointestinal Cancer Disease Group
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 12986-12995 (2023)
Abstract Background Neoadjuvant treatment with nab‐paclitaxel and gemcitabine for potentially operable pancreatic adenocarcinoma has not been well studied in a prospective interventional trial and could down‐stage tumors to achieve negative surgi
Externí odkaz:
https://doaj.org/article/7e8d9dc8460a49968f9cd834b3f15b44
Autor:
Rebecca Ruhl, Shushan Rana, Katherine Kelley, Cristina Espinosa-Diez, Clayton Hudson, Christian Lanciault, Charles R. Thomas, V. Liana Tsikitis, Sudarshan Anand
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Colorectal cancer (CRC) is a leading cause of cancer-related death. The biologic response of CRC to standard of care adjuvant therapies such as chemotherapy and radiation are poorly understood. MicroRNAs (miRs) have been shown to
Externí odkaz:
https://doaj.org/article/84e12b3700074dae815f54c861942d61
Autor:
Amy S. Farrell, Meghan Morrison Joly, Brittany L. Allen-Petersen, Patrick J. Worth, Christian Lanciault, David Sauer, Jason Link, Carl Pelz, Laura M. Heiser, Jennifer P. Morton, Nathiya Muthalagu, Megan T. Hoffman, Sara L. Manning, Erica D. Pratt, Nicholas D. Kendsersky, Nkolika Egbukichi, Taylor S. Amery, Mary C. Thoma, Zina P. Jenny, Andrew D. Rhim, Daniel J. Murphy, Owen J. Sansom, Howard C. Crawford, Brett C. Sheppard, Rosalie C. Sears
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Neuroendocrine differentiation of epithelial tumor cells can contribute to cancer cell resistance and survival. Here, the authors show that dysregulated c-Myc promotes neuroendocrine differentiation in pancreatic ductal adenocarcinoma, leading to poo
Externí odkaz:
https://doaj.org/article/dc766b609bac46f8805ef957d3259818
Autor:
Julia Wattacheril, Erin H Seeley, Peggi Angel, Heidi Chen, Benjamin P Bowen, Christian Lanciault, Richard M Caprioli, Naji Abumrad, Charles Robb Flynn
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57165 (2013)
Nonalcoholic fatty liver disease (NAFLD) occurs frequently in a setting of obesity, dyslipidemia and insulin resistance, but the etiology of the disease, particularly the events favoring progression to nonalcoholic steatohepatitis (NASH) as opposed t
Externí odkaz:
https://doaj.org/article/d36f1707ad9e4983864a942364dd16e1
Autor:
Laura Torrens, Catherine E. Willoughby, Christian Lanciault, Markus Grompe, Josep M. Llovet, David W. Russell, Jordi Abril-Fornaguera, Roser Pinyol, Dhwanil A. Dalwadi, Willscott E. Naugler, Jeffrey Posey
Publikováno v:
Mol Ther
Adeno-associated virus (AAV) integrates into host genomes at low frequency, but when integration occurs in oncogenic hotspots it can cause hepatocellular carcinoma (HCC). Given the possibility of recombinant AAV (rAAV) integration leading to HCC, com
Autor:
Christian Lanciault, Ge Huang, Joe W. Gray, Rachelle Riggers, Young Hwan Chang, Guillaume Thibault, John Muschler, Luke Ternes
Publikováno v:
Scientific Reports
Mechanistic disease progression studies using animal models require objective and quantifiable assessment of tissue pathology. Currently quantification relies heavily on staining methods which can be expensive, labor/time-intensive, inconsistent acro
Autor:
Christian Lanciault, Elizabeth N. Dewey, Rebecca R. Ruhl, Vassiliki L. Tsikitis, Sudarshan Anand, Raphael M. Byrne, Ivy H. Gardner, Katherine M. Watson
Publikováno v:
Dis Colon Rectum
Background Colorectal cancer is a leading cause of cancer-related death. Early onset colorectal cancer (age ≤45 y) is increasing and associated with advanced disease. Although distinct molecular subtypes of colorectal cancer have been characterized
Autor:
Christian Lanciault, Brett Johnson, Mary McDonnell, Joe W. Gray, Erik A. Burlingame, Christopher L. Corless, Young Hwan Chang, Geoffrey F. Schau, Guillaume Thibault, Terry K. Morgan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Spatially-resolved molecular profiling by immunostaining tissue sections is a key feature in cancer diagnosis, subtyping, and treatment, where it complements routine histopathological evaluation by clarifying tumor phenotypes. In this work, we presen
Autor:
Christian Lanciault, Sheila Weinmann, Brett S. Walker, Nicole Wieghard, Melissa H. Wong, Alexandra C. Gallagher, V. Liana Tsikitis, Kevin G. Billingsley, John R. Swain, Luai Zarour
Publikováno v:
World journal of surgery. 44(10)
Colorectal cancer (CRC) ranks second in cancer deaths worldwide and presents multiple management challenges, one of which is identifying high risk stage II disease that may benefit from adjuvant therapy. Molecular biomarkers, such as ones that identi
Autor:
Maria S. Tretiakova, Christian Lanciault, Chris Kizzar, Victoria Krajbich, Randy Woltjer, Dale Davis, Nicole K. Andeen, Scott S. Tykodi
Publikováno v:
Annals of diagnostic pathology. 47
Studies assessing tumor-infiltrating lymphocytes (TILs) in clear cell renal cell carcinoma (ccRCC) and clinical outcomes have mixed results. Given fundamental interaction of MHC class I with CD8+ T-cells, we hypothesized that expression of MHC class